Results 81 to 90 of about 6,189,777 (260)

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Modelling Interval Data with Random Intercepts: A Beta Regression Approach for Clustered and Longitudinal Structures

Modelling
Beta regression models are a class of models used frequently to model response variables in the interval (0, 1). Although there are articles in which these models are used to model clustered and longitudinal data, the prediction of random effects is ...
Olga Usuga-Manco, Freddy Hernández-Barajas, Viviana Giampaoli   +2 more
doaj   +1 more source

An Empirically-Grounded Comparison of the Johnson System versus the Beta as Crop Yield Distribution Models [PDF]

Previous research established that the expanded Johnson system can accommodate any theoretically possible mean-variance-skewness-kurtosis combination.
Ramirez, Octavio A., McDonald, Tanya U.
core  

The polarized expression of Na+,K+-ATPase in epithelia depends on the association between beta-subunits located in neighboring cells [PDF]

, 2005
The polarized distribution of Na+,K+-ATPase plays a paramount physiological role, because either directly or through coupling with co- and countertransporters, it is responsible for the net movement of, for example, glucose, amino acids, Ca2+, K+, Cl ...
Shoshani, L, Balda, MS, Cereijido, M, Matter, K, Moreno, J, Contreras, RG, Roldan, ML, Lazaro, A   +7 more
core  

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

Modelo iterativo para estimativa da evapotranspiração de referência provável Iterative model to estimate probable reference evapotranspiration

Scientia Agricola, 1995
O presente trabalho teve por objetivo a apresentação de um modelo iterativo para utilização em microcomputadores capaz de estimar valores de evapotranspiracão de referencia em diversos níveis de probabilidade, a partir de uma série de dados.
S. Marques Jr, J.C.C. Saad, M.V.T. de Moura   +2 more
doaj   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

Phi Beta Kappa: The Key Reporter Winter 2012-2013

, 2012
Announcement of the Beta of Nebraska chapter installation at Creighton University, p.
Phi Beta Kappa Society
core  

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Beta-PSMC: uncovering more detailed population history using beta distribution. [PDF]

BMC Genomics, 2022
Liu J, Ji X, Chen H.
europepmc   +1 more source