Results 101 to 110 of about 3,133,166 (336)
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
Understanding the processes and mechanisms that shape the distribution patterns and variations of biodiversity along spatial gradients continues to be a priority for ecological research. We focused on the biodiversity of benthic diatom communities within
Naicheng Wu +10 more
doaj +1 more source
Unraveling spatiotemporal variability of arbuscular mycorrhizal fungi in a temperate grassland plot [PDF]
© The Author(s), 2019. This article is distributed under the terms of the Creative Commons Attribution License. The definitive version was published in Goldmann, K., Boeddinghaus, R. S., Klemmer, S., Regan, K. M., Heintz-Buschart, A., Fischer, M., Prati,
Berner, Doreen +12 more
core +2 more sources
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Previous studies have found mixed results regarding the relationship between beta diversity and latitude. In addition, by influencing local environmental heterogeneity, land use may modify spatial taxonomic and functional variability among communities ...
D. Petsch +11 more
semanticscholar +1 more source
An operational, additive framework for species diversity partitioning and beta‐diversity analysis [PDF]
Summary An important goal of community ecology is the assessment of factors that are likely to influence the spatio‐temporal distribution of species assemblages and diversity. Surprisingly, most statistical methods devoted to this have remained poorly interconnected, as well as poorly connected with the popular metrics of diversity estimation.
Pelissier, Raphaël, Couteron, Pierre
openaire +4 more sources
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Integration of circadian and hypoxia signaling via non‐canonical heterodimerization
CLOCK, BMAL1, and HIFs are basic helix‐loop‐helix and Per‐Arnt‐Sim domain (bHLH‐PAS) proteins, which function as transcription factors. bHLH‐PAS proteins are designated in two classes. Many class I proteins are regulated by environmental signals via their PAS domains, but such signals have not been identified for all.
Sicong Wang, Katja A. Lamia
wiley +1 more source
Assessing plant diversity during community succession based on plant trait and phylogenetic features within a community (alpha scale) and among communities (beta scale) could improve our understanding of community succession mechanism.
Yongfu Chai +8 more
doaj +1 more source
Hierarchical coexistence of universality and diversity controls robustness and multi-functionality in intermediate filament protein networks [PDF]
Proteins constitute the elementary building blocks of a vast variety of biological materials such as cellular protein networks, spider silk or bone, where they create extremely robust, multi-functional materials by self-organization of structures over ...
Markus J. Buehler, Theodor Ackbarow
core +1 more source

