Results 81 to 90 of about 1,095,525 (267)

Comparing self‐reported race and genetic ancestry for identifying potential differentially methylated sites in endometrial cancer: insights from African ancestry proportions using machine learning models

Molecular Oncology, EarlyView.
Integrating ancestry, differential methylation analysis, and machine learning, we identified robust epigenetic signature genes (ESGs) and Core‐ESGs in Black and White women with endometrial cancer. Core‐ESGs (namely APOBEC1 and PLEKHG5) methylation levels were significantly associated with survival, with tumors from high African ancestry (THA) showing ...
Huma Asif, J. Julie Kim
wiley   +1 more source

On the integral equation of the boundary value problem for the essentially loaded differential heat operator

Қарағанды университетінің хабаршысы. Математика сериясы, 2016
In the article the Volterra integral equations of the second kind with the given kernel are investigated. This kind of integral equations arises in the solving of some boundary value problems for essential loaded differential heat operator in an ...
A.N. Yesbayev, G.A. Yessenbayeva
doaj  

A new extended Mulholland's inequality involving one partial sum

Open Mathematics
By using the weight coefficients and the techniques of real analysis, a new extended Mulholland’s inequality with multi-parameters involving one partial sum is given. The equivalent statements of the best value related to several parameters are provided.
Peng Ling, Yang Bicheng
doaj   +1 more source

A large‐scale retrospective study in metastatic breast cancer patients using circulating tumour DNA and machine learning to predict treatment outcome and progression‐free survival

Molecular Oncology, EarlyView.
There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes, Mario Ortega Duran, Solon Karapanagiotis, Alistair Martin, Meiling Gao, Riccardo Masina, Ramona Woitek, James Tanner, Fleur Tippin, Justine Kane, Jonathan Lay, Anja Brouwer, Stephen‐John Sammut, Suet‐Feung Chin, Davina Gale, Dana W. Y. Tsui, Sarah‐Jane Dawson, Nitzan Rosenfeld, Maurizio Callari, Oscar M. Rueda, Carlos Caldas   +20 more
wiley   +1 more source

Multidimensional OMICs reveal ARID1A orchestrated control of DNA damage, splicing, and cell cycle in normal‐like and malignant urothelial cells

Molecular Oncology, EarlyView.
Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser, Florian Krumbach, Eyleen Corrales, Geoffroy Andrieux, Christian Preisinger, Franziska Liss, Alexandra Golzmann, Melanie Boerries, Kerstin Becker, Ruth Knüchel, Stefan Garczyk, Bernhard Lüscher   +11 more
wiley   +1 more source

Exact Expressions for Kullback–Leibler Divergence for Multivariate and Matrix-Variate Distributions

Entropy
The Kullback–Leibler divergence is a measure of the divergence between two probability distributions, often used in statistics and information theory. However, exact expressions for it are not known for multivariate or matrix-variate distributions apart ...
Victor Nawa, Saralees Nadarajah
doaj   +1 more source

Tonic signaling of the B‐cell antigen‐specific receptor is a common functional hallmark in chronic lymphocytic leukemia cell phosphoproteomes at early disease stages

Molecular Oncology, EarlyView.
B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez, Pablo Juanes‐Velasco, Marina L. García‐Vaquero, Conrad Droste, Alicia Landeira‐Viñuela, Miguel Alcoceba, Helena Fidalgo‐Gómez, Sara Misiego‐Herrero, Almudena Navarro‐Bailón, Mónica Baile, José M. Bastida, Jose Manuel Sanchez‐Santos, Rafael Góngora, Julia Almeida, Marcos Gonzalez‐Diaz, Alberto Orfao, Javier De Las Rivas, Manuel Fuentes   +17 more
wiley   +1 more source

Intrinsic sympathomimetic activity of cardioselective beta‐adrenoceptor blockers and effects on renal function. [PDF]

, 1985
I. G. Mackay, AM Macnicol, HJ Smith, A. D. Cumming, ML Watson   +4 more
openalex   +1 more source

Assessing Liver Function in Beta-Thalassemia Patients: Exploring Blood Transfusion-Related Complications

, 2023
Pallavi Kharde Sudhir Sarawade
openalex   +1 more source

Latent transforming growth factor beta binding protein 4: A regulator of mitochondrial function in acute kidney injury [PDF]

, 2023
Kit Neikirk, Adaku C. Ume, Praveena Prasad, Andrea G. Marshall, Jananie Rockwood, Tara‐Yesomi Wenegieme, Kelia McMichael, Melanie R. McReynolds, Clintoria R. Williams, Antentor Hinton   +9 more
openalex   +1 more source