Results 91 to 100 of about 1,044,930 (284)

Premarital screening test results for beta thalassemia in Malatya Province

open access: yesMedicine Science, 2021
Hemoglobinopathies are the most common monogenic hereditary diseases worldwide. After sickle-cell disease, beta thalassemia has the highest incidence. Premarital screening is performed to detect beta thalassemia carriers and prevent pathological births ...
Mehmet Erten
doaj   +1 more source

BETA THALASSEMIA

open access: yesThe Professional Medical Journal, 2018
Background: Inadequate Blood Transfusion is responsible for various problemsin children with Thalasseima. On the other hand, repeated transfusions are related with hazards.About 25-50% of the children with thalassemia major have impaired glucose ...
Iqbal Ahmed   +6 more
semanticscholar   +1 more source

Understanding erythroid physiology and pathology in humanized mice: A closer look

open access: yesBritish Journal of Haematology, Volume 206, Issue 5, Page 1272-1284, May 2025.
Erythropoiesis, the formation of red blood cells (RBCs) from haematopoietic stem cells (HSCs), is vital for understanding conditions like anaemia and haemoglobinopathies. However, studying this process in vivo is challenging due to the lack of accurate models.
Lu Lu   +7 more
wiley   +1 more source

Prevalence and intensity of depression in mothers of children with beta-thalassemia major in Talghani Hospital of Gorgan, Iran [PDF]

open access: yes, 2014
Background: Thalassemia is a chronic disease that it leads to psychological and social problems for parents. Mothers are at markedly increased risk of suffering from psychological distress and depression because they usually take on a considerable part ...
Jahazi, A.   +3 more
core  

Mithramycin encapsulated in polymeric micelles by microfluidic technology as novel therapeutic protocol for beta-thalassemia [PDF]

open access: yes, 2012
This report shows that the DNA-binding drug, mithramycin, can be efficiently encapsulated in polymeric micelles (PM-MTH), based on Pluronic® block copolymers, by a new microfluidic approach.
Brognara, Eleonora   +8 more
core   +2 more sources

Lack of awareness about thalassemia; a social factor in the propagation of beta thalassemia gene in Pakistan: A population study

open access: yesMediterranean Journal of Hematology and Infectious Diseases, 2014
Background: Beta thalassemia is the most common genetic disorder in Pakistan. Thalassemia is a preventive disease a fact well demonstrated by countries such as Italy, Greece and Cyprus.
Muhammad Usman
doaj  

Dukungan Keluarga Dalam Merawat Anak Dengan Thalassemia Beta Mayor

open access: yesCitra Delima, 2019
ABSTRAK Pendahuluan: Thalassemia merupakan penyakit anemia hemolitik yang diturunkan secara genetik. Indonesia termasuk salah satu Negara yang memiliki penduduk pembawa gena thalassemia dengan prevalensi sebesar 3-8%. Anak thalassemia beta mayor harus
Rezka Nurvinanda   +3 more
doaj   +1 more source

Long‐term efficacy and safety of mitapivat in non‐transfusion‐dependent α‐ or β‐thalassaemia: An open‐label phase 2 study

open access: yesBritish Journal of Haematology, EarlyView.
Mitapivat is an oral activator of pyruvate kinase (PK), the enzyme responsible for the final step in glycolysis, and increases production of adenosine triphosphate (ATP), which may lead to improvements in red blood cell health, ineffective erythropoiesis and haemolysis.
Kevin H. M. Kuo   +9 more
wiley   +1 more source

HUBUNGAN ANTARA STRES DENGAN STRATEGI COPING PADA ORANG TUA YANG MEMILIKI ANAK PENDERITA TALASEMIA BETA MAYOR DI RUMAH SAKIT UMUM DAERAH DR. ZAINOEL ABIDIN BANDA ACEH [PDF]

open access: yes, 2013
Background: Beta thalassemia major is a disorder characterized by defective hemoglobin production and excessive destruction of red blood cells. This life-threatening illnesses suffered by children can lead to parental stress and depression. How to cope
RINA SYAFRITA
core  

The role of red blood cell characteristics and viscosity in sickle cell retinopathy and maculopathy

open access: yesBritish Journal of Haematology, EarlyView.
Sickle cell retinopathy and maculopathy are common ocular complications of sickle cell disease. This study assessed the contribution of red blood cell characteristics and blood viscosity to their development. HbSC patients with proliferative retinopathy showed a lower delta elongation index and point of sickling, while no link was found between whole ...
Rajani P. Brandsen   +8 more
wiley   +1 more source

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