Results 91 to 100 of about 1,048,085 (335)
Pathophysiology and treatment of patients with beta-thalassemia – an update
F1000Research, 2017 Thalassemia (thal) is an autosomal recessive, hereditary, chronic hemolytic anemia due to a partial or complete deficiency in the synthesis of α-globin chains (α-thal) or β-globin chains (β-thal) that compose the major adult hemoglobin (α 2β 2).
E. Fibach, E. Rachmilewitz
semanticscholar +1 more source
Lipid Nanoparticles for Delivery of CRISPR Gene Editing Components
Small Methods, EarlyView.The review presents a comprehensive overview of each component of lipid nanoparticles（LNPs）and their effects on editing efficiency. It specifically highlights strategies for achieving non‐liver delivery, aiming for broader applications in gene editing. Furthermore, this review summarizes the applications of LNPs in gene editing and offers insights for ...
Fan Wu +6 more
wiley +1 more source
Beta Thalassemia: An Overview of Epidemiology, Clinical Features, Diagnosis, and Management [PDF]
پزشکی بالینی ابن سیناBackground and Objective: Thalassemia is an inherited blood disorder with an autosomal recessive inheritance pattern caused by the reduced or absent production of globin chains.
Ghasem Miri-Aliabad
doaj
Dukungan Keluarga Dalam Merawat Anak Dengan Thalassemia Beta Mayor
Citra Delima, 2019 ABSTRAK Pendahuluan: Thalassemia merupakan penyakit anemia hemolitik yang diturunkan secara genetik. Indonesia termasuk salah satu Negara yang memiliki penduduk pembawa gena thalassemia dengan prevalensi sebesar 3-8%. Anak thalassemia beta mayor harus
Rezka Nurvinanda +3 more
doaj +1 more source
Effects of vitamin e and zinc supplementation on antioxidants in beta thalassemia major patients [PDF]
, 2011 Objective: In beta thalassemic patients, tissue damage occurs due to oxidative stress and it happens because of the accumulation of iron in the body. This study was conducted to determine the effect of zinc and vitamin E supplementation on antioxidant ...
Aboomardani, M. +5 more
core +1 more source
Small Structures, EarlyView.This work developed a PDC nanoplatform that orchestrated a multimodal synergistic therapy, combining active targeting, photothermal therapy, and iron nutrient deprivation. The antifungal, anti‐inflammatory efficacy and corneal repair ability of nanoplatform were demonstrated through both in vitro and in vivo evaluations.
Ruojiao Feng +13 more
wiley +1 more source
Prevalence of Minor β-thalassemia Based on RBC Indices among Final Suspected Individuals in Premarital Screening Program Referred to Genetic Laboratories [PDF]
International Journal of Hematology-Oncology and Stem Cell Research, 2010 "nAbstract "nIntroduction: The current study evaluated the value of red blood cell (RBC) indices and the corresponding cut- off points for β-thalassemia control programs in Iran.
Alireza Moafi +5 more
doaj
A Child Lost to Follow Up Carrying Beta Thalassemia Major: A Case Report
Journal of Nepal Medical Association, 2020 Thalassemia is inherited autosomal recessive disorders characterized by reduced rate of hemoglobin synthesis due to a defect in alpha or beta globin chain synthesis. Maldives has a beta thalassemia prevalence rate of 16–18%.
Prakash Banjade, Jeetendra Bhandari
doaj +1 more source
Aging Cell, EarlyView.Humanized mice offer new insight into immune‐hormonal changes during menopause. Traditional models lack accuracy in replicating human menopause physiology. Functional foods may ease symptoms but need testing in human‐relevant systems. Combining humanized mice with diet research can improve women's health outcomes.
Nisansala Chandimali +6 more
wiley +1 more source
Mutation analysis of β-thalassemia in East-Western Indian population: a recent molecular approach
The Application of Clinical Genetics, 2017 Parth S Shah,1 Nidhi D Shah,2 Hari Shankar P Ray,3 Nikunj B Khatri,3 Ketan K Vaghasia,3 Rutvik J Raval,4 Sandip C Shah,3 Mandava V Rao5 1Department of Medicine, Lahey Hospital and Medical Center, Boston, MA, 2Department of Pediatrics, Nassau University ...
Shah PS +7 more
doaj