Results 91 to 100 of about 1,051,766 (308)

Basiliximab in the Prophylaxis of aGVHD for Unrelated Donor Hematopoietic Stem Cell Transplantation in Patients With Thalassemia Major: A Prospective, Multicenter, Open‐Label, Randomized Controlled Study

American Journal of Hematology, EarlyView.
Zhenbin Wei, Rongrong Liu, Lingling Shi, Qiaochuan Li, Lianjin Liu, Baoshi Zheng, Chunjie Qin, Hong Chen, Guyun Wang, Meiqing Wu, Gaohui Yang, Ruolin Li, Zhaoping Gan, Qi Zhou, Jing Fan, Xuemei Zhou, Yinghua Chen, Zhiyu Zeng, Zhongming Zhang, Yongrong Lai   +19 more
wiley   +1 more source

Making Advanced Therapies Affordable and Accessible: Two Strategic Approaches

Developing World Bioethics, EarlyView.
ABSTRACT This article explores two complementary strategies for addressing the affordability and access challenges facing advanced therapies. As high development costs and limited market access have led to the withdrawal of several therapies, the article examines how these barriers create ‘valleys of death’ that prevent innovation from reaching ...
Ubaka Ogbogu, Lauren Albrecht
wiley   +1 more source

Association Between Thalassemia and Leucocytic DNA Damage: A Pilot Study

Journal of Basic and Applied Research in Biomedicine, 2022
Objectives: Thalassemia with frequent blood transfusion was considered under oxidative stress because of the chance of iron overload. Patients with thalassemia trait with no blood transfusion might also suffered from oxidative stress because of ...
Yim Szeto, Charlton CHAN
doaj   +2 more sources

Prevalence of Candida albicans in the oral cavity of Beta Thalassemia Major and Thalassemia Minor Patients [version 1; peer review: 2 approved]

F1000Research
Aims To examine the correlation between iron, ferritin concentrations, and C. albicans infection in individuals with beta-thalassemia major and beta-thalassemia minor compared with healthy subjects.
Maha Adel Mahmood, Saba Sami Abd Al Wahab   +1 more
doaj   +1 more source

Human parvovirus B19 in patients with beta thalassemia major from Tehran, Iran

Blood Research, 2017
Background Due to the tropism of human parvovirus B19 to erythroid progenitor cells, infection in patients with an underlying hemolytic disorder such as beta-thalassemia major leads to suppression of erythrocyte formation, referred to as transient ...
S. Arabzadeh, F. Alizadeh, A. Tavakoli, H. Mollaei, F. Bokharaei-Salim, G. Karimi, M. Farahmand, H. Mortazavi, S. Monavari   +8 more
semanticscholar   +1 more source

HUBUNGAN ANTARA STRES DENGAN STRATEGI COPING PADA ORANG TUA YANG MEMILIKI ANAK PENDERITA TALASEMIA BETA MAYOR DI RUMAH SAKIT UMUM DAERAH DR. ZAINOEL ABIDIN BANDA ACEH [PDF]

, 2013
Background: Beta thalassemia major is a disorder characterized by defective hemoglobin production and excessive destruction of red blood cells. This life-threatening illnesses suffered by children can lead to parental stress and depression. How to cope
RINA SYAFRITA
core  

Nonsense-mediated decay mechanism is a possible modifying factor of clinical outcome in nonsense cd39 beta thalassemia genotype [PDF]

, 2012
Nonsense-mediated mRNA decay (NMD) is a surveillance system to prevent the synthesis of non-functional proteins. In β-thalassemia, NMD may have a role in clinical outcome.
ATTANASIO, Massimo, Calvaruso, G, Cassarà, F, Fecarotta, E, Fiorentino, G, Giambona, A, Maggio, A., Piazza, A, Renda, D, Renda, MC, Rigano, P, VITRANO, Angela   +11 more
core   +1 more source

Pubertal Assessment and Growth in Patients With Hemoglobinopathies: A Longitudinal Multicenter Study on the Association With Ferritin Levels

European Journal of Haematology, EarlyView.
ABSTRACT Objectives Although Advancements in the Treatment of Hemoglobinopathies have Considerably Increased Life Expectancy, Hormonal and Pubertal Development Have Been Continuously Affected by Complications From Transfusion‐Related Iron Overload and Cytotoxic Therapies.
J. Dülberg, C. Sanchez, M.‐A. Burckhardt, L. Alacán Friedrich, V. Salow, A. Radauer‐Plank, A. Borgmann‐Staudt, H. Cario, M. Diepold, B. Drexler, L. Infanti, S. Kroiss, N. Dietliker, R. Merki, L. Njue, L. Oevermann, A. Rovó, K. Scheinemann, M. Schneider, M. Balcerek, T. Diesch‐Furlanetto   +20 more
wiley   +1 more source

Pulmonary hypertension in adolescents with sickle cell disease [PDF]

, 2016
Sickle cell disease consists of a group of disorders that have a similar mutation in at least one of the beta-globin chains of hemoglobin. This results in a change of the hemoglobin to sickle shaped cells when in the deoxygenated state.
Akinyemi, Katherine
core   +1 more source

Calibration of myocardial T2 and T1 against iron concentration. [PDF]

, 2014
BACKGROUND: The assessment of myocardial iron using T2* cardiovascular magnetic resonance (CMR) has been validated and calibrated, and is in clinical use.
A John Baksi, Adam Fleming, AW Nienhuis, B Leonardi, B Modell, B Modell, CJ Yong-Hing, CM Wacker, D Verhaert, David N Firmin, DH Fitchett, DI Thickman, DR Messroghli, Dudley J Pennell, G Abbruzzese, GA Krombach, Gianluca Forni, Gildo Matta, Greg Black, Gualtiero Catani, H Miskin, J Malcolm Walker, JC Hsu, JC Wood, JC Wood, JH Jensen, JK Olynyk, John B Porter, John C Wood, John-Paul Carpenter, JP Carpenter, LA Saryan, Lisa J Anderson, LJ Anderson, LJ Anderson, LJ Olson, LJ Olson, M Barry, M Tovi, M Westwood, MA Tanner, MA Westwood, Mary N Sheppard, MD Cerqueira, Michael Roughton, Mike House, MW Garbowski, N Koizumi, NR Ghugre, P Kirk, Paul Kirk, PD Jensen, PT Telfer, RL Kamman, RL Kamman, SI Mavrogeni, SK Piechnik, Sofia V de Noronha, Suthat Fucharoen, T He, T He, T He, T He, Taigang He, TG St Pierre, Timothy G St. Pierre, W Chua-anusorn, W Collins, W Hosch, Y Feng   +69 more
core   +1 more source