Efficacy of lactoferrin oral administration in the treatment of anemia and anemia of inflammation in pregnant and non-pregnant women: an interventional study [PDF]
, 2018 The discovery of the ferroportin-hepcidin complex has led to a critical review on the treatment of anemia and anemia of inflammation (AI). Ferroportin, the only known mammalian iron exporter from cells to blood, is negatively regulated by hepcidin, a ...
Antimo Cutone +6 more
core +2 more sources
Journal of Blood Medicine, 2018 Chanchai Traivaree,1 Chalinee Monsereenusorn,1 Piya Rujkijyanont,1 Warakorn Prasertsin,2 Boonchai Boonyawat3 1Division of Hematology/Oncology, Department of Pediatrics, Phramongkutklao Hospital and College of Medicine, Bangkok, Thailand; 2Department of ...
Traivaree C +4 more
doaj
Prevalence of Minor β-thalassemia Based on RBC Indices among Final Suspected Individuals in Premarital Screening Program Referred to Genetic Laboratories [PDF]
International Journal of Hematology-Oncology and Stem Cell Research, 2010 "nAbstract "nIntroduction: The current study evaluated the value of red blood cell (RBC) indices and the corresponding cut- off points for β-thalassemia control programs in Iran.
Alireza Moafi +5 more
doaj
British Journal of Haematology, EarlyView.Summary Patients with transfusion‐dependent thalassaemia (TDT) require chronic, life‐sustaining red blood cell transfusions, which contribute to iron overload and associated morbidity and mortality. Luspatercept, an inhibitor of the transforming growth factor‐beta pathway, decreases transfusion requirements in a subset of transfusion‐dependent β ...
Bianca Zaidel +2 more
wiley +1 more source
Third-degree heart block in thalassemia major: A case report [PDF]
, 2012 Background: First and second-degree heart blocks are partly common rhythm disorders in thalassemic patients but complete heart block is a very rare complication of iron overload cardiomyopathy.
Hosseini, S.M., Maleki, A.R., Nikyar, B.
core +1 more source
Human parvovirus B19 in patients with beta thalassemia major from Tehran, Iran
Blood Research, 2017 Background Due to the tropism of human parvovirus B19 to erythroid progenitor cells, infection in patients with an underlying hemolytic disorder such as beta-thalassemia major leads to suppression of erythrocyte formation, referred to as transient ...
S. Arabzadeh +8 more
semanticscholar +1 more source
Prime Editing: A Revolutionary Technology for Precise Treatment of Genetic Disorders
Cell Proliferation, Volume 58, Issue 4, April 2025.This review outlines the latest research advancements in prime editing technology, delivery strategies, and the challenges that must be addressed to fully realize its therapeutic potential, emphasizing the high potential of prime editing in the remission or cure of genetic diseases. ABSTRACT Genetic diseases have long posed significant challenges, with
Mengyao Li, Yi Lin, Qiang Cheng, Tuo Wei
wiley +1 more source
Intervention and Prevention of Hereditary Hemolytic Disorders in Two Ethnic Communities of Sundargarh District of Orissa, India: An Experience from KAP Studies [PDF]
, 2010 Hereditary hemolytic disorders are important public health challenges in India. They cause a high degree of morbidity, mortality and fetal wastage in vulnerable communities.
Balgir, RS
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Beta Thalassemia: An Overview of Epidemiology, Clinical Features, Diagnosis, and Management [PDF]
پزشکی بالینی ابن سیناBackground and Objective: Thalassemia is an inherited blood disorder with an autosomal recessive inheritance pattern caused by the reduced or absent production of globin chains.
Ghasem Miri-Aliabad
doaj
Critical values for the $β$-transformation with a hole at $0$ [PDF]
arXiv, 2021 Given $\beta\in(1,2]$, let $T_\beta$ be the $\beta$-transformation on the unit circle $[0,1)$ such that $T_\beta(x)=\beta x\pmod 1$. For each $t\in[0,1)$ let $K_\beta(t)$ be the survivor set consisting of all $x\in[0,1)$ whose orbit $\{T^n_\beta(x): n\ge 0\}$ never hits the open interval $(0,t)$. Kalle et al. proved in [Ergodic Theory Dynam.
arxiv