The role of iron in normal and impaired testicular function
Abstract Iron plays a critical role in testicular physiology, impacting spermatogenesis, testosterone production, and overall testicular function. Iron homeostasis is maintained through systemic and cellular regulatory mechanisms, including hepcidin‐mediated systemic iron control and the iron‐responsive element/iron regulatory protein (IRE/IRP) system ...
Aileen Harrer+2 more
wiley +1 more source
ABSTRACT Aim This study tested the relationship between the hospitalisation experience and distress among Jewish and Bedouin parents of hospitalised children in the south of Israel. Methods An anonymous self‐reported questionnaire containing the Distress Thermometer for Parents and the Parental Perceptions of Hospital Care in Children was completed by ...
Elena Gelman+2 more
wiley +1 more source
Mutation analysis of β-thalassemia in East-Western Indian population: a recent molecular approach
Parth S Shah,1 Nidhi D Shah,2 Hari Shankar P Ray,3 Nikunj B Khatri,3 Ketan K Vaghasia,3 Rutvik J Raval,4 Sandip C Shah,3 Mandava V Rao5 1Department of Medicine, Lahey Hospital and Medical Center, Boston, MA, 2Department of Pediatrics, Nassau University ...
Shah PS+7 more
doaj
Study of Pregnancy Outcome in E-Beta Thalassaemia Mothers [PDF]
Forty eight E-Beta thalassaemia patients were studied in NRS Medical College, Kolkata, West Bengal during the period from 2000-2006. In all patients Hb% ranged from 5.2g% - 9.6g%.
Bhattacharyaya, Maitryaee+1 more
core +1 more source
Refractory anaemia in a patient with end‐stage heart failure secondary to aortic stenosis
ESC Heart Failure, EarlyView.
Jiayu Liang, Suxin Luo, Bi Huang
wiley +1 more source
Oxidative stress and antioxidant status in beta-thalassemia heterozygotes
Background: Several studies have evaluated the oxidant and antioxidant status of thalassemia patients but most focused mainly on the severe and intermediate states of the disease.
Luciana de Souza Ondei+6 more
doaj +1 more source
Intervention and Prevention of Hereditary Hemolytic Disorders in Two Ethnic Communities of Sundargarh District of Orissa, India: An Experience from KAP Studies [PDF]
Hereditary hemolytic disorders are important public health challenges in India. They cause a high degree of morbidity, mortality and fetal wastage in vulnerable communities.
Balgir, RS
core +1 more source
Appraisal of patient-reported outcome measures in analogous diseases and recommendations for use in phase II and III clinical trials of pyruvate kinase deficiency [PDF]
Purpose: Pyruvate kinase deficiency (PKD) is a rare disease and understanding of its epidemiology and associated burden remains limited. With no current curative therapy, clinical manifestations can be life threatening, clinically managed by maintaining ...
Ionova, Tatyana+3 more
core +2 more sources
Iron overload and morbidities in Chinese with non‐transfusion‐dependent thalassaemia
A cross‐sectional study in Hong Kong included 109 adult and paediatric Chinese patients with non‐transfusion dependent thalassaemia (NTDT). The study found significant chronic health issues in 52% of patients. More severe disease was observed in patients with non‐deletional α‐thalassaemia intermedia, β‐thalassaemia intermedia, advanced age and history ...
Wing‐yan Leung+19 more
wiley +1 more source
Fetomaternal haemorrhage (FMH) in RhD‐negative individuals can cause alloimmunization with future antibody‐mediated destruction of fetal red blood cells. Accurate FMH estimation guides Rh immune globulin dosing. The rosette test, the most used qualitative method, may yield false negatives with fetal RhD variants or false positives with maternal ...
Omar I. Hajjaj+5 more
wiley +1 more source