Results 61 to 70 of about 1,014,717 (317)

Calibration of myocardial T2 and T1 against iron concentration. [PDF]

, 2014
BACKGROUND: The assessment of myocardial iron using T2* cardiovascular magnetic resonance (CMR) has been validated and calibrated, and is in clinical use.
A John Baksi, Adam Fleming, AW Nienhuis, B Leonardi, B Modell, B Modell, CJ Yong-Hing, CM Wacker, D Verhaert, David N Firmin, DH Fitchett, DI Thickman, DR Messroghli, Dudley J Pennell, G Abbruzzese, GA Krombach, Gianluca Forni, Gildo Matta, Greg Black, Gualtiero Catani, H Miskin, J Malcolm Walker, JC Hsu, JC Wood, JC Wood, JH Jensen, JK Olynyk, John B Porter, John C Wood, John-Paul Carpenter, JP Carpenter, LA Saryan, Lisa J Anderson, LJ Anderson, LJ Anderson, LJ Olson, LJ Olson, M Barry, M Tovi, M Westwood, MA Tanner, MA Westwood, Mary N Sheppard, MD Cerqueira, Michael Roughton, Mike House, MW Garbowski, N Koizumi, NR Ghugre, P Kirk, Paul Kirk, PD Jensen, PT Telfer, RL Kamman, RL Kamman, SI Mavrogeni, SK Piechnik, Sofia V de Noronha, Suthat Fucharoen, T He, T He, T He, T He, Taigang He, TG St Pierre, Timothy G St. Pierre, W Chua-anusorn, W Collins, W Hosch, Y Feng   +69 more
core   +1 more source

A novel transgenic reporter of extracellular acidification in zebrafish elucidates skeletal muscle T‐tubule pH regulation

Developmental Dynamics, EarlyView.
Abstract Disruption of extracellular pH and proton‐sensing can profoundly impact cellular and protein functions, leading to developmental defects. To visualize changes in extracellular pH in the developing embryo, we generated a zebrafish transgenic line that ubiquitously expresses the ratiometric pH‐sensitive fluorescent protein pHluorin2, tethered to
Leif R. Neitzel, Maya Silver, Aaron H. Wasserman, Samantha Rea, Charles C. Hong, Charles H. Williams   +5 more
wiley   +1 more source

Prevalence of Co-Inheritance of Alpha-Thalassemia with Beta-Thalassemia and Beta-Hemoglobinopathy in Ahvaz City

Journal of Ardabil University of Medical Sciences, 2013
Background: Co-inheritance of hemoglobin gene defects is a rare important status that can lead to double heterozygote or homozygote with significant clinical manifestations. Such conditions can be observed in co-inheritance of alpha-thalassemia with beta-
Najmaddin Saki, Akbar Dorgalaleh, Zahra Kashani Khatib, Shaban Alizadeh, Fakher Rahim, Hamid Galehdari, Bijan Kaikhaei, Mohammad Pedram, Ali Dehghani Fard   +8 more
doaj  

Brain perfusion changes in beta-thalassemia. [PDF]

Orphanet J Rare Dis
Abstract Background Brain injury in hereditary hemoglobinopathies is commonly attributed to anemia-related relative hypoperfusion in terms of impaired oxygen blood supply. Supratentorial and infratentorial vascular watershed regions seem to be especially vulnerable, but data are very scarce.
Manara R, Ponticorvo S, Contieri M, Canna A, Russo AG, Fedele MC, Rocco MC, Borriello A, Valeggia S, Pennisi M, De Angelis M, Roberti D, Cirillo M, di Salle F, Perrotta S, Esposito F, Tartaglione I.   +16 more
europepmc   +5 more sources

Theorizing Beta Thalassemia Major: an Overview of Health Sociology

RIMCIS, 2020
This research focuses on specific models of health and illness, explored by many researchers across the world. The sequential variations and critic of each model is summed up by researcher and the relevant theoretical orientations of beta thalassemia ...
Muhammad Abo ul Hassan Rashid, Saif-Ur-Rehman Saif Abbasi   +1 more
doaj   +1 more source

Premarital screening test results for beta thalassemia in Malatya Province

Medicine Science, 2021
Hemoglobinopathies are the most common monogenic hereditary diseases worldwide. After sickle-cell disease, beta thalassemia has the highest incidence. Premarital screening is performed to detect beta thalassemia carriers and prevent pathological births ...
Mehmet Erten
doaj   +1 more source

Premature atherosclerosis in children with beta-thalassemia major: New diagnostic marker

BMC Pediatrics, 2017
BackgroundEarly vascular alteration, atherosclerosis and coronary artery disease have emerged as important cardiovascular complications among beta-thalassemia major (B-TM) patients. The aims of the current study were to assess the prevalence of premature
L. Sherief, Osama Dawood, Adel S A Ali, H. Sherbiny, N. Kamal, Mohamed Elshanshory, Osama Abd Alazez, M. A. Alhady, M. Nour, Wesam A. Mokhtar   +9 more
semanticscholar   +1 more source

Efficacy of lactoferrin oral administration in the treatment of anemia and anemia of inflammation in pregnant and non-pregnant women: an interventional study [PDF]

, 2018
The discovery of the ferroportin-hepcidin complex has led to a critical review on the treatment of anemia and anemia of inflammation (AI). Ferroportin, the only known mammalian iron exporter from cells to blood, is negatively regulated by hepcidin, a ...
Antimo Cutone, Antimo Cutone, Luigi Rosa, Maria Pia Conte, Maria Stefania Lepanto, Piera Valenti, Rosalba Paesano   +6 more
core   +2 more sources

Current Progress in Targeting Human Cytomegalovirus Infection

iLABMED, EarlyView.
This review highlights recent advances in the mechanisms by which human cytomegalovirus (HCMV) maintains its genome in infected cells, as well as the cellular factors and viral antigens that modulate viral reactivation, which reveal potential targets for addressing HCMV infection.
Yonggang Pei, Jun Chen
wiley   +1 more source

Classification of β-Thalassemia Carriers From Red Blood Cell Indices Using Ensemble Classifier

IEEE Access, 2021
Thalassemia is viewed as a prevalent inherited blood disease that has gotten exorbitant consideration in the field of medical research around the world. Inherited diseases have a high risk that children will get these diseases from their parents. If both
Saima Sadiq, Muhammad Usman Khalid, Mui-Zzud-Din, Saleem Ullah, Waqar Aslam, Arif Mehmood, Gyu Sang Choi, Byung-Won On   +7 more
doaj   +1 more source