COVID-19: perspectivas terapéuticas en IL-17/Th17
Las células T helper-17 (Th17) y la interleuquina (IL) IL-17 desempeñan funciones biológicas relacionadas con la protección contra infecciones por bacterias extracelulares y hongos.
Franky Úsuga-Úsuga +2 more
doaj +1 more source
Structural mapping of antibody landscapes to human betacoronavirus spike proteins [PDF]
AbstractPreexisting immunity against seasonal coronaviruses (CoV) represents an important variable in predicting antibody responses and disease severity to Severe Acute Respiratory Syndrome CoV-2 (SARS-2) infections. We used electron microscopy based polyclonal epitope mapping (EMPEM) to characterize the antibody specificities against β-CoV spike ...
Sandhya Bangaru +11 more
openaire +2 more sources
Conserved host-pathogen interactions identify novel treatment options in betacoronavirus infections [PDF]
Hypoxia is an underlying pathophysiological condition of a variety of devastating diseases, including acute ischemic stroke (AIS). We are faced with limited therapeutic options for AIS patients, and even after successful restoration of cerebral blood flow, the poststroke mortality is still high.
Lukassen, Soeren, Eils, Roland
openaire +4 more sources
MERS–Related Betacoronavirus inVespertilio superansBats, China [PDF]
(Uploaded by Plazi for the Bat Literature Project) No abstract provided.
Li Yang +10 more
openaire +4 more sources
Sub‐second heat inactivation of coronavirus using a betacoronavirus model [PDF]
AbstractHeat treatment denatures viral proteins that comprise the virion, making the virus incapable of infecting a host. Coronavirus (CoV) virions contain single‐stranded RNA genomes with a lipid envelope and four proteins, three of which are associated with the lipid envelope and thus are thought to be easily denatured by heat or surfactant‐type ...
Yuqian Jiang +7 more
openaire +2 more sources
Group C Betacoronavirus in Bat Guano Fertilizer, Thailand [PDF]
To the Editor: Bats play a critical role in the transmission and origin of zoonotic diseases, primarily viral zoonoses associated with high case-fatality rates, including those caused by Nipah virus (NiV) and severe acute respiratory syndrome (SARS)–like coronavirus (CoV) infections (1).
Supaporn Wacharapluesadee +11 more
openaire +3 more sources
Novel Betacoronavirus in Dromedaries of the Middle East, 2013 [PDF]
In 2013, a novel betacoronavirus was identified in fecal samples from dromedaries in Dubai, United Arab Emirates. Antibodies against the recombinant nucleocapsid protein of the virus, which we named dromedary camel coronavirus (DcCoV) UAE-HKU23, were detected in 52% of 59 dromedary serum samples tested.
Mareena, R +13 more
openaire +4 more sources
Repurposing Interleukin-6 Inhibitors to Combat COVID-19. [PDF]
Severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) is a pandemic with major implications across the world. One of the most frequent causes of death from SARS-CoV-2 is fatal pneumonia from coronavirus disease 2019 (COVID-19), which is associated
Kato, Shumei, Kurzrock, Razelle
core +1 more source
COVID-19: etiology, clinical picture, treatment
Whereas the XX century marked the history of acute respiratory disease investigation as a period for generating in-depth system of combating influenza viruses (Articulavirales: Orthomyxoviridae, Alpha-/Betainfluenzavirus) (based on environmental and ...
M. Yu. Shchelkanov +4 more
doaj +1 more source
Lineage A betacoronavirus NS2 proteins and the homologous torovirus Berne pp1a carboxy-terminal domain are phosphodiesterases that antagonize activation of RNase L [PDF]
Viruses in the family Coronaviridae, within the order Nidovirales, are etiologic agents of a range of human and animal diseases, including both mild and severe respiratory diseases in humans.
Chen, Annie I +9 more
core +2 more sources

