Results 71 to 80 of about 37,714 (159)

Human Betacoronavirus 2c EMC/2012–related Viruses in Bats, Ghana and Europe [PDF]

Emerging Infectious Diseases, 2013
(Uploaded by Plazi for the Bat Literature Project) We screened fecal specimens of 4,758 bats from Ghana and 272 bats from 4 European countries for betacoronaviruses. Viruses related to the novel human betacoronavirus EMC/2012 were detected in 46 (24.9%) of 185 Nycteris bats and 40 (14.7%) of 272 Pipistrellus bats.
Augustina Annan, Heather Baldwin, Victor M. Corman, Stefan M. Klose, Michael Owusu, Evans Ewald Nkrumah, Ebenezer K. Badu, Priscilla Anti, Olivia Agbenyega, Benjamin Meyer, Samuel Oppong, Yaw Adu Sarkodie, Elisabeth K. V. Kalko, Peter H. C. Lina, Lena Godlevska, Chantal Reusken, Antje Seebens, Florian Gloza‐Rausch, Peter Vallo, Marco Tschapka, Christian Drosten, Jan Felix Drexler   +21 more
openaire   +5 more sources

Hallmarks of Alpha- and Betacoronavirus non-structural protein 7+8 complexes [PDF]

Science Advances, 2020
Coronaviral nsp7+8 complexes follow species- and stoichiometry-specific assembly pathways determined by few amino acid changes.
Krichel, Boris, Bylapudi, Ganesh, Schmidt, Christina, Blanchet, Clement, Schubert, Robin, Brings, Lea, Koehler, Martin, Zenobi, Renato, Svergun, Dmitri, Lorenzen, Kristina, Madhugiri, Ramakanth, Ziebuhr, John, Uetrecht, Charlotte   +12 more
openaire   +6 more sources

Viral Immunity in Immunoglobulin Products: Global Immunity Debt and Autoimmunity in the Postpandemic Era

European Journal of Immunology, Volume 56, Issue 3, March 2026.
Immunoglobulin products derived from pooled global plasma reflect population‐level antiviral immunity. Analysis of batches from 2017 to 2023 reveals pandemic‐driven shifts in viral antibody profiles and a concurrent rise in autoantibodies, notably against TRIM21/Ro52, highlighting links between SARS‐CoV‐2, immunity debt, and autoimmunity.
Hannes Lindahl, Katy Shaw‐Saliba, H. Benjamin Larman, C. I. Edvard Smith, Peter Bergman   +4 more
wiley   +1 more source

Discovery and Characterization of a Pan-betacoronavirus S2-binding antibody

Structure
SUMMARY/ABSTRACTThree coronaviruses have spilled over from animal reservoirs into the human population and caused deadly epidemics or pandemics. The continued emergence of coronaviruses highlights the need for pan-coronavirus interventions for effective pandemic preparedness.
Johnson, Nicole V., Wall, Steven C., Kramer, Kevin J., Holt, Clinton M., Periasamy, Sivakumar, Richardson, Simone, Suryadevara, Naveenchandra, Andreano, Emanuele, Paciello, Ida, Pierleoni, Giulio, Piccini, Giulia, Huang, Ying, Ge, Pan, Allen, James D., Uno, Naoko, Shiakolas, Andrea R., Pilewski, Kelsey A., Nargi, Rachel S., Sutton, Rachel E., Abu-Shmais, Alexandria A., Parks, Robert, Haynes, Barton F., Carnahan, Robert H., Crowe, James E., Montomoli, Emanuele, Rappuoli, Rino, Bukreyev, Alexander, Ross, Ted M., Sautto, Giuseppe A., McLellan, Jason S., Georgiev, Ivelin S.   +30 more
openaire   +4 more sources

Evaluation of nine serological rapid tests for the detection of SARS-CoV-2

Revista Panamericana de Salud Pública, 2020
Objective. To evaluate the operative capacity of nine serological rapid tests to detect the IgM/IgG antibodies response in serum from patients with SARS-CoV-2 in different clinical stages. Methods.
Marcela Mercado, Jeadran Malagón-Rojas, Gabriela Delgado, Vivian Vanesa Rubio, Lida Muñoz Galindo, Eliana L. Parra Barrera, Paula Gaviria, Gabriela Zabaleta, Zonia Alarcon, Adriana Arévalo, Helly Casallas Cifuentes, Kelly Estrada, Gloria Puerto, María T. Herrera Sepúlveda, Helena Rodríguez, Marisol Galindo, Martha Lucía Ospina Ramírez   +16 more
doaj   +1 more source

Structural Basis of MERS‐CoV Receptor Interactions and Antibody Neutralisations

Reviews in Medical Virology, Volume 36, Issue 2, March 2026.
ABSTRACT Increasing outbreaks of coronaviruses underscore the importance of antivirals and vaccines that can combat a wide range of coronaviruses. Neutralising antibodies (nAbs), along with vaccines and small‐molecule drugs, are among the most promising treatments and prevention options against coronaviruses.
Edem Gavor, Yeu Khai Choong, Sunil Singh, Hariharan Sivaraman, Er Shi Yin, J. Sivaraman   +5 more
wiley   +1 more source

Cross‐Reactive IgG Antibody Responses to SARS‐CoV‐2 in Older Adults Following Seasonal Coronavirus Infection in Jiangsu, China (2015–2017)

Influenza and Other Respiratory Viruses, Volume 20, Issue 3, March 2026.
ABSTRACT The extent of cross‐reactive antibodies to SARS‐CoV‐2 elicited by seasonal human coronaviruses (HCoVs) remains unclear. We analyzed longitudinal preinfection and postinfection IgG responses in 62 older adults with PCR‐confirmed HCoV infections from sera collected prior to the emergence of SARS‐CoV‐2.
Cheng Xiao, Nancy H. L. Leung, Shiman Ling, Xia Lin, Yuyun Chen, Yanmin Xie, Malik Peiris, Mark Zanin, Benjamin Cowling, Sook‐San Wong   +9 more
wiley   +1 more source

Strategic Preparedness of Broad‐Spectrum Antivirals for Rapid Response Towards Next Pandemics

Small Science, Volume 6, Issue 1, January 2026.
Nanoengineered broad‐spectrum antivirals (BSAs) represent a transformative approach to pandemic preparedness. Unlike virus‐specific drugs requiring separate development, BSAs act across multiple viral families through nanoengineering strategies that enhance solubility, bioavailability, and host‐targeted activity.
Sanoj Rejinold N, Geun‐woo Jin, Jin‐Ho Choy   +2 more
wiley   +1 more source

Attenuated Infectious Bronchitis Virus (IBV) Vaccination Induces Protective Humoral and Cellular Immunity Against SARS‐CoV‐2 in Mammals

Journal of Immunology Research, Volume 2026, Issue 1, 2026.
Occupational exposure to infectious bronchitis virus (IBV) has been associated with cross‐reactivity to other coronaviruses such as SARS‐CoV‐2. In this study, we investigated the immune response of IBV using reconstituted samples of the commercial H120 Mass‐I vaccine (Zoetis) against SARS‐CoV‐2 infection.
Ney de Carvalho Almeida, Mauricio Fraga van Tilburg, Bruno Bezerra da Silva, João Xavier da Silva Neto, Luiz Francisco Wemmenson Gonçalves Moura, Natália do Vale Canabrava, Diane Isabelle Magno Cavalcante, Deysi Viviana Tenazoa Wong, Roberto César Pereira Lima Júnior, Daniel Pascoalino Pinheiro, Dayane Alves Costa, Danúbio Andrade Bezerra Farias, Pablo Abreu de Morais, Valder Nogueira Freire, Valdir Ferreira de Paula Junior, Francisco Franciné Maia Júnior, Diego Veras Wilke, Gilvan Pessoa Furtado, Eridan Orlando Pereira Tramontina Florean, Maria Izabel Florindo Guedes, Poorani Gurumallesh   +20 more
wiley   +1 more source

The Tetrahydroisoquinoline Derivative SP9 Exhibits Antiviral Activity Against PEDV and MHV

Transboundary and Emerging Diseases, Volume 2026, Issue 1, 2026.
Coronaviruses exhibit high mutation rates and cross‐species transmissibility, posing a persistent threat to human and animal health and underscoring the urgent need for antivirals that can compensate for the limited crossprotection afforded by current vaccines.
Junhai Zhu, Yuting Jiang, Kaifang Yang, Fei Gao, Wenbao Qi, Lihong Huang, Yue Wang, Bin Li   +7 more
wiley   +1 more source