Results 61 to 70 of about 114,626 (394)

Investigation of betaine as a novel psychotherapeutic for schizophreniaResearch in context

EBioMedicine, 2019
Background: Betaine is known to act against various biological stresses and its levels were reported to be decreased in schizophrenia patients. We aimed to test the role of betaine in schizophrenia pathophysiology, and to evaluate its potential as a ...
Tetsuo Ohnishi, Shabeesh Balan, Manabu Toyoshima, Motoko Maekawa, Hisako Ohba, Akiko Watanabe, Yoshimi Iwayama, Yuko Fujita, Yunfei Tan, Yasuko Hisano, Chie Shimamoto-Mitsuyama, Yayoi Nozaki, Kayoko Esaki, Atsuko Nagaoka, Junya Matsumoto, Mizuki Hino, Nobuko Mataga, Akiko Hayashi-Takagi, Kenji Hashimoto, Yasuto Kunii, Akiyoshi Kakita, Hirooki Yabe, Takeo Yoshikawa   +22 more
doaj   +1 more source

The association of serum betaine concentrations with the risk of new-onset cancers: results from two independent nested case-control studies

Nutrition & Metabolism, 2023
Evidence from epidemiologic studies on the association of circulating betaine levels with the incident risk of cancer has been inconsistent. We aimed to investigate the prospective association of serum betaine concentrations with the risk of cancer.
Hailun Xie, Kangping Zhang, Yaping Wei, Guotian Ruan, Heyang Zhang, Shuqun Li, Yun Song, Ping Chen, Lishun Liu, Binyan Wang, Hanping Shi   +10 more
doaj   +1 more source

Betaine Supplementation May Improve Heat Tolerance: Potential Mechanisms in Humans

Nutrients, 2020
Betaine has been demonstrated to increase tolerance to hypertonic and thermal stressors. At the cellular level, intracellular betaine functions similar to molecular chaperones, thereby reducing the need for inducible heat shock protein expression.
Brandon D. Willingham, Tristan J Ragland, M. Ormsbee   +2 more
semanticscholar   +1 more source

Incomplete Wood-Ljungdahl pathway facilitates one-carbon metabolism in organohalide-respiring Dehalococcoides mccartyi. [PDF]

, 2014
The acetyl-CoA "Wood-Ljungdahl" pathway couples the folate-mediated one-carbon (C1) metabolism to either CO2 reduction or acetate oxidation via acetyl-CoA.
Alvarez-Cohen, Lisa, Bill, Markus, Brisson, Vanessa L, Conrad, Mark E, Feng, Xueyang, Men, Yujie, Tang, Yinjie J, Yi, Shan, Zhuang, Wei-Qin   +8 more
core   +1 more source

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

FEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies, Garth L. Maker, Ian F. Musgrave, Samantha Lodge   +3 more
wiley   +1 more source

Betaine affects muscle lipid metabolism via regulating the fatty acid uptake and oxidation in finishing pig

Journal of Animal Science and Biotechnology, 2017
Background Betaine affects fat metabolism in animals, but the specific mechanism is still not clear. The purpose of this study was to investigate possible mechanisms of betaine in altering lipid metabolism in muscle tissue in finishing pigs.
Sisi Li, Haichao Wang, Xinxia Wang, Yizhen Wang, Jie Feng   +4 more
doaj   +1 more source

Effects of short-term betaine supplementation on muscle endurance and indices of endocrine function following acute high-intensity resistance exercise in young athletes

Journal of the International Society of Sports Nutrition, 2022
Objective This study examined the effects of short-term betaine supplementation on muscle endurance, plasma lactate, testosterone and cortisol levels, and the testosterone to cortisol (T/C) ratio in response to acute resistance exercise (RE).
Hamid Arazi, Shima Aboutalebi, Behzad Taati, Jason M. Cholewa, Darren G. Candow   +4 more
doaj   +1 more source

The role of exogenous glycinebetaine on some antioxidant activity of non-T and T tobacco (Nicotiana tabacum L.) under in vitro salt stress

Acta Agriculturae Slovenica, 2021
Glycine betaine is an osmoprotectant compound which enhances cell tolerance in plant species in response to environmental stresses. This study aimed to investigate the effect of exogenous application of glycine betaine on some antioxidant activities of ...
Marzeih VAHID DASTJERDI, Ali Akbar EHSANPOUR, Amir Hossein FORGHANI   +2 more
doaj   +1 more source

Impact of dietary changes on hepatic homocysteine metabolism in young broilers [PDF]

, 2004
Information regarding the impact of sulfur amino acids (SAA) on hepatic homocysteine (Hcy) flux through the various metabolic pathways competing for Hcy in young broilers is lacking. An experiment was conducted to evaluate the impact of varying levels of
Emmert, Jason L., Ganson, Fauna M., Pillai, Padmakumar   +2 more
core   +2 more sources

Betaine chemistry, roles, and potential use in liver disease [PDF]

, 2016
Background Betaine is the trimethyl derivative of glycine and is normally present in human plasma due to dietary intake and endogenous synthesis in liver and kidney.
Day, Christopher R., Kempson, Stephen A.
core   +1 more source