Results 81 to 90 of about 15,211 (150)

Betaine restores epigenetic control and supports neuronal mitochondria in the cuprizone mouse model of multiple sclerosis

Epigenetics, 2020
Methionine metabolism is dysregulated in multiple sclerosis (MS). The methyl donor betaine is depleted in the MS brain where it is linked to changes in levels of histone H3 trimethylated on lysine 4 (H3K4me3) and mitochondrial impairment. We investigated
Naveen K. Singhal, Sarah Sternbach, Sheila Fleming, Kholoud Alkhayer, John Shelestak, Daniela Popescu, Alyx Weaver, Robert Clements, Brandi Wasek, Teodoro Bottiglieri, Ernest J. Freeman, Jennifer McDonough   +11 more
doaj   +1 more source

Betaine decreases hepatic lipid deposition through DNA 5 mC and RNA m6A methylation-mediated regulation of fatty acid metabolic genes expression in laying hens

Poultry Science
As a methyl donor, betaine participates in hepatic lipid metabolism in mammals. Nevertheless, it is unclear whether and how dietary betaine affects hepatic lipid metabolism in laying hens.
Yuxin Yang, Xumin Jin, Dengfeng Lu, Yulin Wu, Fanchi Meng, Minyu Zhang, Jiaojiao Wang, Xiaoyan Cui, Tingting Li, Shengchen Wang, Xugang Luo, Yun Hu   +11 more
doaj   +1 more source

betaines

, 2014
Citation: 'betaines' in the IUPAC Compendium of Chemical Terminology, 3rd ed.; International Union of Pure and Applied Chemistry; 2006. Online version 3.0.1, 2019. 10.1351/goldbook.B00637 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms.
openaire   +1 more source

Relationship between Dietary Protein Levels and Betaine Supplementation in Laying Hens

The Journal of Poultry Science, 2011
The effects of betaine supplementation on productivity, egg quality, blood components, and liver amino acid concentration were examined in laying hens using a diet with differing levels of CP.
Jae-Hong Park, Kyeong-Seon Ryu
doaj   +1 more source

Metabolic Effects of Betaine: A Randomized Clinical Trial of Betaine Supplementation in Prediabetes

, 2018
ContextPlasma betaine correlates with insulin sensitivity in humans. Betaine supplementation improves metabolic effects in mice fed a high-fat diet.ObjectiveTo assess metabolic effects of oral betaine in obese participants with prediabetes.DesignA 12 ...
Ana Maria Grizales, Jonathan M Dreyfuss, Hui Pan, Mary-Elizabeth Patti, Adrienne Lee, Chisayo Kozuka, V Anik Sahni, David M Pober, Kristen M Fowler, Robert E Gerszten, Allison B Goldfine, Alexander P Lin, Joshua A Beckman, Emilie Cloutier, Rita Basu   +14 more
core   +1 more source

Evidence for mitochondrial localization of betaine aldehyde dehydrogenase in rat liver - purification, characterization and comparison with human cytoplasmic E3 isozyme

, 2013
Betaine aldehyde dehydrogenase has been purified to homogeneity from rat liver mitochondria. The properties of betaine aldehyde dehydrogenase were similar to those of human cytoplasmic E3 isozyme in substrate specificity and kinetic constants for ...
Pietruszko, Regina, Chern, Ming-kai; Pietruszko, Regina   +1 more
core  

Antioxidant effects of betaine against Indomethacin-induced gastric damage in rats

Majallah-i Dānishgāh-i ’Ulūm-i Pizishkī-i Shahīd Ṣadūqī Yazd, 2016
Introduction: Betaine (trimethyl glycine) is known as methyl group donor and antioxidant in previous reports. The aim of this study was to assess the antioxidant effects of betaine in Indomethacin-induced gastric damages.
M Alirezaei, N Khalighian, H Shokrani, N Tanideh   +3 more
doaj  

Gabapentin drug interactions in water and aqueous solutions of green betaine based compounds through volumetric, viscometric and interfacial properties

Scientific Reports
Betaine as a bio-based surfactant, has been found in a variety of natural sources. Betaine improves drug absorption, protect drugs from degradation, and enhance the performance of various therapeutic and hygiene products. To investigate the interactions
Elaheh Janbezar, Hemayat Shekaari, Mohammad Bagheri   +2 more
doaj   +1 more source

Role of betaine in improving the antidepressant effect of S-adenosyl-methionine in patients with mild-to-moderate depression

, 2015
Francesco Di Pierro,1 Rossana Orsi,2 Roberto Settembre31Scientific Department, Velleja Research, Milan, Italy; 2ASL TO1, Turin, Italy; 3Neurosurgery Department, ASL BA, Di Venere Hospital, Bari, ItalyBackground: S-adenosyl-methionine (SAMe) is a common ...
Orsi R, Settembre R, Di Pierro F
core  

Distribution of de novo synthesized betaine in rat kidney: role of renal synthesis on medullary betaine accumulation

, 1997
The trimethylamine glycine-betaine is accumulated to high concentrations in medullary cells of mammalian kidneys, whereas betaine synthesis from choline is predominant in the renal cortex.
G. W. Moeckel, Y. H. Lien
core   +1 more source