Results 91 to 100 of about 45,886 (260)

Impact of Stabilizing Osmolytes on the Conformational Dynamics of Human and Rat Islet Amyloid Polypeptides

Proteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT The aggregation of human islet amyloid polypeptide (hIAPP) into cytotoxic oligomers and amyloid fibrils is a hallmark of type 2 diabetes mellitus (T2DM), leading to pancreatic β‐cell dysfunction. In contrast, rat IAPP (rIAPP) is largely non‐amyloidogenic. Osmolytes such as glucose, glycerol, and sorbitol are known to stabilize globular protein
Kiara A. Kidman, Claudio Pedrick, Cara A. Kreck, Ricardo L. Mancera   +3 more
wiley   +1 more source

Antioxidant effects of betaine against Indomethacin-induced gastric damage in rats

Majallah-i Dānishgāh-i ’Ulūm-i Pizishkī-i Shahīd Ṣadūqī Yazd, 2016
Introduction: Betaine (trimethyl glycine) is known as methyl group donor and antioxidant in previous reports. The aim of this study was to assess the antioxidant effects of betaine in Indomethacin-induced gastric damages.
M Alirezaei, N Khalighian, H Shokrani, N Tanideh   +3 more
doaj  

Gabapentin drug interactions in water and aqueous solutions of green betaine based compounds through volumetric, viscometric and interfacial properties

Scientific Reports
Betaine as a bio-based surfactant, has been found in a variety of natural sources. Betaine improves drug absorption, protect drugs from degradation, and enhance the performance of various therapeutic and hygiene products. To investigate the interactions
Elaheh Janbezar, Hemayat Shekaari, Mohammad Bagheri   +2 more
doaj   +1 more source

European Society of Contact Dermatitis Guideline for Diagnostic Patch Testing—Recommendations on Best Practice (Update 2026)

Contact Dermatitis, EarlyView.
ABSTRACT The present guideline updates the initial ESCD patch testing guideline, summarizing all aspects of patch testing for the diagnosis of contact allergy in patients suspected of suffering, or having been suffering, from allergic contact dermatitis or other delayed‐type hypersensitivity skin and mucosal conditions. Sections with brief descriptions
Wolfgang Uter, Olivier Aerts, Tove Agner, Richard Brans, Magnus Bruze, Alicia Cannavó, Marie‐Noёlle Crépy, Ana M. Giménez‐Arnau, Margarida Gonçalo, An Goossens, Swen M. John, Carola Lidén, Suzana Ljubojević Hadžavdić, Vera Mahler, Mihaly Matura, Esen Özkaya, Maria Pesonen, Nadia Raison‐Peyron, Thomas Rustemeyer, Radoslaw Spiewak, Luca Stingeni, Ian R. White, S. Mark Wilkinson, Jeanne Duus Johansen   +23 more
wiley   +1 more source

Betaine eliminates CFA-induced depressive-like behaviour in mice may be through inhibition of microglia and astrocyte activation and polarization

Brain Research Bulletin
Chronic pain can induce not only nociceptive but also depressive emotions. A previous study demonstrated that betaine, a commonly used nutrient supplement, has an anti-nociceptive effect, but whether betaine can alleviate chronic pain-induced depressive ...
Yue Liang, Ling Chen, Yanmei Huang, Lihua Xie, Xueqin Liu, Wenyan Zhou, Wenyu Cao, Zuyao Chen, Xiaolin Zhong   +8 more
doaj   +1 more source

Contrasting effects of different molecular crowding environments on base‐pair opening/closing dynamics of DNA triplex structures

The FEBS Journal, EarlyView.
Base‐pair opening and closing regulate nucleic‐acid structure, stability, and function, but how these motions behave under intracellular molecular crowding remains unclear. Using NMR, we quantified these dynamics in a DNA triplex under two crowder‐reconstituted environments that mimic cellular crowding.
Tomoki Sakamoto, Yudai Yamaoki, Takashi Nagata, Masato Katahira   +3 more
wiley   +1 more source

Compatibility of personal care thickening polymers in sulphate‐free surfactants

International Journal of Cosmetic Science, EarlyView.
Phase behaviour for alpha olefin sulfonate surfactant 10–15 wt% combined with 1 wt% sodium carboxy methyl cellulose, clearly indicating the sensitivity in miscibility when adding various levels of background salt. Abstract Objective Formulators today know that when traditional surfactants and polymers are replaced new problems occur. What was before a ‘
Tobias Halthur, Jonas Carlstedt, Marta Gubitosi, Debora W. Chang, Eric S. Johnson   +4 more
wiley   +1 more source

Targeted keratin repair: A plant‐based approach to hair strength and surface restoration

International Journal of Cosmetic Science, EarlyView.
Application of Avena strigosa seed extract may reinforce keratin bonding, restoring hair fibre integrity by promoting intramolecular interactions at damaged sites of keratin proteins. Abstract Objective Chemical and thermal stress disrupts the intramolecular and intermolecular interactions that stabilize hair keratin, leading to structural degradation ...
Emina Besic Gyenge, Loya Schoeffel, Stefan Hettwer, Andreas Bosch, Cosimo Kropp, Brigit Suter, Barbara Obermayer   +6 more
wiley   +1 more source

The Complex World of Toothpaste Diversity, Meeting Patient Clinical Needs. An Umbrella Review

International Journal of Dental Hygiene, EarlyView.
ABSTRACT Background Amidst numerous recent advancements in toothpaste formulations and active ingredients, some clinicians may believe all toothpastes are similar despite differences in their active ingredients and corresponding clinical application.
Jeanie Suvan, Crystal Marruganti
wiley   +1 more source

THE OXIDATION OF BETAINE ALDEHYDE BY BETAINE ALDEHYDE DEHYDROGENASE

Journal of Biological Chemistry, 1954
H A, ROTHSCHILD, E S G, BARRON
openaire   +2 more sources