Results 21 to 30 of about 7,885 (162)
Cell Reports, 2017 Summary: BET inhibitors (BETi) target bromodomain-containing proteins and are currently being evaluated as anti-cancer agents. We find that maximal therapeutic effects of BETi in a Myc-driven B cell lymphoma model required an intact host immune system ...
Simon J. Hogg +17 more
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Molecular Plant-Microbe Interactions, 2003 The symbiotic soil bacterium Sinorhizobium meliloti has the capacity to synthesize the osmoprotectant glycine betaine from choline-O-sulfate and choline.
Karine Mandon +6 more
doaj +1 more source
Cells, 2022 Atherosclerosis is an important risk factor in the development of cardiovascular diseases. In addition to increased plasma lipid concentrations, irregular/oscillatory shear stress and inflammatory processes trigger atherosclerosis.
Johannes Jarausch +7 more
doaj +1 more source
Oncogenesis, 2021 Targeting the epigenome to modulate gene expression programs driving cancer development has emerged as an exciting avenue for therapeutic intervention.
Jack Calder +4 more
doaj +1 more source
Cell Reports, 2018 Summary: BRD4 plays a major role in the transcription networks orchestrated by androgen receptor (AR) in castration-resistant prostate cancer (CRPC). Several BET inhibitors (BETi) that displace BRD4 from chromatin are being evaluated in clinical trials ...
Aishwarya Pawar +3 more
doaj +1 more source
Ionic Liquid Electrolytes for Extreme Temperature Conditions: Challenges and Perspective
Angewandte Chemie, EarlyView.Ionic liquids (ILs) have gained great attention as safe electrolyte components in recent years. This review elucidates the temperature effects on IL‐based electrolytes from molecular configurations, physicochemical properties, and interfacial chemistry, raises the challenges and design strategies operating at low‐ and HT, providing valuable guidance ...
En Xie +11 more
wiley +2 more sources
Resistance to BET Bromodomain Inhibitors Is Mediated by Kinome Reprogramming in Ovarian Cancer
Cell Reports, 2016 Small-molecule BET bromodomain inhibitors (BETis) are actively being pursued in clinical trials for the treatment of a variety of cancers, but the mechanisms of resistance to BETis remain poorly understood.
Alison M. Kurimchak +15 more
doaj +1 more source
PERSEPSI MASYARAKAT TERHADAP KONTEN YOUTUBE ARIF MUHAMMAD ‘MAK BETI’ [PDF]
, 2023 Tujuan dalam penelitian ini merupakan buat mengenali data serta memperoleh informasi tentang Persepsi Masyarakat Terhadap Konten Youtube Arif Muhammad ‘Mak Beti’.
Arifana, Arifana -
core +1 more source