Bevacizumab in the Treatment of Breast Cancer: Rationale and Current Data [PDF]
Hope S. Rugo
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New trend in molecular diagnostics: Insights from the tumor microenvironment
The graphical abstract outline the key elements in TME‐based molecular diagnostics, including biomarker exploration, diagnostic methods, and diagnostic models. Source: Created with BioRender.com. Abstract Molecular diagnosis has revolutionized cancer precision medicine.
Baiyuan Fan +3 more
wiley +1 more source
ABSTRACT Hepatocellular carcinoma (HCC) is the most common subtype of primary liver cancer, with significant variability in patient outcomes even within the same stage according to the Barcelona Clinic Liver Cancer staging system. Accurately predicting patient prognosis and potential treatment response prior to therapy initiation is crucial for ...
Feng Che +5 more
wiley +1 more source
Addition of Bevacizumab to Bolus Fluorouracil and Leucovorin in First-Line Metastatic Colorectal Cancer: Results of a Randomized Phase II Trial [PDF]
Fairooz F. Kabbinavar +9 more
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Pharmacology and Pharmacodynamics of Bevacizumab as Monotherapy or in Combination with Cytotoxic Therapy in Preclinical Studies [PDF]
Hans‐Peter Gerber, Napoleone Ferrara
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USP28 Promotes Osimertinib Resistance in H1975 NSCLC Cells by Deubiquitinating and Stabilizing SIRT1
ABSTRACT Osimertinib (OSI) resistance in non‐small cell lung cancer (NSCLC) remains a significant challenge. This report explored the precise role of USP28 on OSI resistance in NSCLC and identified a functional downstream effector. OSI‐resistant H1975 cells (H1975/OSI) were established by long‐term OSI exposure.
Hu‐Sen Fan +4 more
wiley +1 more source
Impact of Vascular Endothelial Growth Factor-A Expression, Thrombospondin-2 Expression, and Microvessel Density on the Treatment Effect of Bevacizumab in Metastatic Colorectal Cancer [PDF]
Adrian M. Jubb +11 more
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ABSTRACT Epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs) are indicated for advanced lung adenocarcinoma patients harboring susceptible EGFR mutations. The aim of this retrospective study was to compare the effectiveness of different generations of EGFR TKIs.
Chia‐Yu Kuo +9 more
wiley +1 more source
Surgical Resection After Downsizing of Colorectal Liver Metastasis in the Era of Bevacizumab [PDF]
Lee M. Ellis +2 more
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