Results 171 to 180 of about 216,339 (397)

New trend in molecular diagnostics: Insights from the tumor microenvironment

open access: yesInterdisciplinary Medicine, EarlyView.
The graphical abstract outline the key elements in TME‐based molecular diagnostics, including biomarker exploration, diagnostic methods, and diagnostic models. Source: Created with BioRender.com. Abstract Molecular diagnosis has revolutionized cancer precision medicine.
Baiyuan Fan   +3 more
wiley   +1 more source

Emerging Role of MRI‐Based Artificial Intelligence in Individualized Treatment Strategies for Hepatocellular Carcinoma: A Narrative Review

open access: yesJournal of Magnetic Resonance Imaging, EarlyView.
ABSTRACT Hepatocellular carcinoma (HCC) is the most common subtype of primary liver cancer, with significant variability in patient outcomes even within the same stage according to the Barcelona Clinic Liver Cancer staging system. Accurately predicting patient prognosis and potential treatment response prior to therapy initiation is crucial for ...
Feng Che   +5 more
wiley   +1 more source

Addition of Bevacizumab to Bolus Fluorouracil and Leucovorin in First-Line Metastatic Colorectal Cancer: Results of a Randomized Phase II Trial [PDF]

open access: bronze, 2005
Fairooz F. Kabbinavar   +9 more
openalex   +1 more source

USP28 Promotes Osimertinib Resistance in H1975 NSCLC Cells by Deubiquitinating and Stabilizing SIRT1

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Osimertinib (OSI) resistance in non‐small cell lung cancer (NSCLC) remains a significant challenge. This report explored the precise role of USP28 on OSI resistance in NSCLC and identified a functional downstream effector. OSI‐resistant H1975 cells (H1975/OSI) were established by long‐term OSI exposure.
Hu‐Sen Fan   +4 more
wiley   +1 more source

Impact of Vascular Endothelial Growth Factor-A Expression, Thrombospondin-2 Expression, and Microvessel Density on the Treatment Effect of Bevacizumab in Metastatic Colorectal Cancer [PDF]

open access: bronze, 2005
Adrian M. Jubb   +11 more
openalex   +1 more source

Clinical Outcomes of Different Generation EGFR TKIs in Susceptible EGFR‐Mutated Advanced Nonsmall‐Cell Lung Cancer

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs) are indicated for advanced lung adenocarcinoma patients harboring susceptible EGFR mutations. The aim of this retrospective study was to compare the effectiveness of different generations of EGFR TKIs.
Chia‐Yu Kuo   +9 more
wiley   +1 more source

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