Results 151 to 160 of about 85,257 (242)

Tumor Infiltrating Lymphocyte Therapy Combined With PD‐1/LAG‐3 Inhibition in Patients With Recurrent Platinum‐Resistant Ovarian Cancer

open access: yesInternational Journal of Cancer, Volume 159, Issue 7, Page 1735-1749, 1 October 2026.
The detection of tumor‐infiltrating lymphocytes (TILs) is a positive prognostic factor in ovarian cancer. Moreover, TILs are significantly boosted by immunotherapy, though ovarian cancer patients have seen limited benefit from immune therapies. This study investigated the safety and feasibility of TIL therapy combined with PD‐1 and LAG‐3 inhibitors in ...
Tine J. Monberg   +9 more
wiley   +1 more source

A 51‐year‐old female presenting with headache and vision loss

open access: yes
Headache: The Journal of Head and Face Pain, EarlyView.
Laurel Ovrom   +3 more
wiley   +1 more source

Plasma PlGF as a Potential Biomarker in Ramucirumab‐Based Second‐Line Therapy for Advanced Gastroesophageal Adenocarcinoma: Exploratory Biomarker Analysis from the Phase II Part of the RAMIRIS Trial

open access: yesInternational Journal of Cancer, Volume 159, Issue 7, Page 1817-1828, 1 October 2026.
Antiangiogenic treatment with ramucirumab is a standard second‐line option in advanced gastric and gastroesophageal junction adenocarcinoma. However, reliable biomarkers are currently lacking. This exploratory biomarker analysis of the RAMIRIS trial suggests that elevated baseline and early on‐treatment levels of the pro‐angiogenic placental growth ...
Jurek Hille   +17 more
wiley   +1 more source

Surviving the Nucleus Pulposus Desert: Next‐Generation Strategies for Intervertebral Disc Cell Therapy

open access: yesJOR SPINE, Volume 9, Issue 3, September 2026.
ABSTRACTBackgroundLow back pain remains the leading cause of disability worldwide, with intervertebral disc degeneration representing a major biological contributor. Although cell‐based therapies have shown promise in preclinical models, clinical translation has yielded modest and inconsistent outcomes.
Tynhinane Hamidouche   +9 more
wiley   +1 more source

Dual‐Drug‐Loaded Liposomes: Design Strategies, Mechanistic Insights, and Therapeutic Applications in Cancer

open access: yesMedComm – Biomaterials and Applications, Volume 5, Issue 3, September 2026.
Dual‐drug‐loaded liposomes enable the simultaneous delivery of hydrophilic and hydrophobic therapeutics to tumors, enhancing anticancer efficacy and overcoming multidrug resistance. Through rational formulation design and surface functionalization, these systems improve tumor targeting, modulate efflux mechanisms and EMT, and achieve synergistic ...
Neelam Sinha   +4 more
wiley   +1 more source

New perspectives on VEGF signalling in Alzheimer's disease

open access: yesBrain Pathology, Volume 36, Issue 5, September 2026.
Emery et al. bring together findings from recent multi‐omic studies, including single‐cell mRNA analysis of human post‐mortem brain tissue, and proteomic analysis of matched CSF and blood samples in large clinical studies. The authors present evidence of the involvement of altered VEGF signalling in vascular and immune dysfunction and neurodegeneration
Cherelle E. G. Emery   +2 more
wiley   +1 more source

Home - About - Disclaimer - Privacy