Reduced Local Tumor Progression After Thermal Ablation During Atezolizumab Plus Bevacizumab Treatment for Hepatocellular Carcinoma. [PDF]
Nakabori T +13 more
europepmc +1 more source
Harnessing Repurposed Drugs to Enhance Temozolomide Efficacy in Glioblastoma
ABSTRACT Background Glioblastoma (GB) is the most aggressive primary malignant brain tumor in adults and remains associated with poor survival despite surgical resection followed by radiotherapy and temozolomide (TMZ) chemotherapy. Intrinsic and acquired resistance to TMZ, including MGMT‐dependent DNA repair and activation of pro‐survival pathways ...
Ali Nakhaei +5 more
wiley +1 more source
Expanding horizons of intravitreal anti-vascular endothelial growth factor therapy in retinal diseases. [PDF]
Singh S, Kala U, Bamel A, Agarwal M.
europepmc +1 more source
Hypoxia, oncogenic signaling, transcriptional and epigenetic remodeling, and H. pylori–microbiota interactions drive the Warburg effect in gastric cancer. Enhanced glycolysis and lactate export support biosynthesis, remodel the tumor microenvironment, promote stromal activation and immune suppression, and reveal actionable biomarkers and therapeutic ...
Guanmo Liu +7 more
wiley +1 more source
Efficacy and safety of first-line therapies for persistent, recurrent, or metastatic cervical cancer: a systematic review and exploratory network meta-analysis of immunotherapy. [PDF]
Wang X +5 more
europepmc +1 more source
ABSTRACT Background and Aims Circulating tumor DNA (ctDNA) has emerged as a promising biomarker of tumor burden and minimal residual disease. As total neoadjuvant therapy (TNT) increasingly supports organ‐preserving strategies in locally advanced rectal cancer (LARC), reliable markers of treatment response are needed.
Faizan Bashir +4 more
wiley +1 more source
Benign Migratory Glossitis in a Patient With Cholangiocarcinoma due to Targeted Drug Therapy. [PDF]
Gurav S, Singh GP, Jain R.
europepmc +1 more source
What's New? Lung cancer patients with COVID‐19 experience significantly increased risk for severe illness and mortality. However, research addressing the effect of COVID‐19 on non‐small cell lung cancer (NSCLC) patients treated with epidermal growth factor receptor (EGFR)‐tyrosine kinase inhibitors (TKIs) remains unknown.
Wenjie Tang +13 more
wiley +1 more source
[<sup>89</sup>Zr]bevacizumab PET/CT imaging of vestibular schwannomas for the prediction of bevacizumab treatment effect in patients with symptomatic <i>NF2</i>-related schwannomatosis: a study protocol for a phase II single centre, prospective, feasibility trial. [PDF]
Douwes JPJ +16 more
europepmc +1 more source

