Results 181 to 190 of about 85,257 (242)

Beyond a Metabolite: Lactylation as a Pivotal Regulator of Colorectal Cancer Pathogenesis and Treatment Resistance

Journal of Biochemical and Molecular Toxicology, Volume 40, Issue 8, August 2026.
This review elucidates how lactylation, a novel histone modification driven by lactate, regulates colorectal cancer pathogenesis. We summarize its roles in tumor progression, metastasis, stemness, immunosuppression, and therapy resistance, and discusses the promising therapeutic strategies of targeting the lactylation pathway.
Shuilan Yao, Yun Liang, Xinwen Liang, Qisheng Su, Xiaohong Li   +4 more
wiley   +1 more source

Cost Analysis of Anti-VEGF With Laser Photocoagulation in the Treatment of Retinopathy of Prematurity at an Academic Referral Center. [PDF]

J Vitreoretin Dis
Patel NA, Mahmoudinezhad G, Hoyek S, Chaaya C, Islam Y, Agarwal-Sinha S.   +5 more
europepmc   +1 more source

Lack of Differences in the Pharmacokinetics of Therapeutic Monoclonal Antibodies Between Japanese and Non‐Japanese Individuals

The Journal of Clinical Pharmacology, Volume 66, Issue 8, August 2026.
Abstract Evaluation of the pharmacokinetics (PK) of new drugs in Japanese individuals is regularly requested by the Japanese regulatory agency prior to participation in global clinical trials or for bridging approaches for regulatory approval. However, the need for PK assessments in the Japanese population may be less compelling for monoclonal ...
Paridhi Gupta, Ashish Sharma, Bernd Meibohm   +2 more
wiley   +1 more source

Advancements in Glioblastoma Multiforme Treatment: A Comprehensive Systematic Review and Meta-Analysis. [PDF]

Brain Behav
Agboola K, Khafaji F, Chaurasia B, Qureshi K, Yangi K, Chavda V, Balak N.   +6 more
europepmc   +1 more source

Management of Satellite Lesions in Hepatocellular Carcinoma: An Updated Review

Journal of Surgical Oncology, Volume 134, Issue 2, Page 157-165, August 2026.
ABSTRACT Satellite lesions, defined as microscopic or small macroscopic tumor nodules within 2 cm of a primary hepatocellular carcinoma (HCC), represent early intrahepatic dissemination and are strongly associated with aggressive tumor biology.
Andy Tran, Mohammed O. Suraju, Ihuoma Tasie, Abdelrahman K. Abdalla, Hassan Aziz   +4 more
wiley   +1 more source

An oncologic cardiotoxicity masquerading as ST-elevated myocardial infarction: a case report. [PDF]

Eur Heart J Case Rep
Singh AK, Rafiudeen R, Wong C.
europepmc   +1 more source

Patient Perspectives on Systemic Bevacizumab Treatment for Recurrent Respiratory Papillomatosis

Laryngoscope Investigative Otolaryngology, Volume 11, Issue 4, August 2026.
In this cross‐institutional survey of 24 patients with recurrent respiratory papillomatosis who had undergone both systemic bevacizumab and surgical treatment, patients reported significantly better voice, breathing, swallowing, and mental well‐being with bevacizumab, along with less pain, fewer side effects, and fewer missed workdays.
Sarah Gao, Jada Jones, Vasiliki Triantafillou, Lee M. Akst, Alexander T. Hillel, Kevin M. Motz, Adam M. Klein, Simon R. Best   +7 more
wiley   +1 more source

AAT score based on pretreatment indicators predicts outcomes in unresectable HCC patients treated with TACE, Sintilimab, and Bevacizumab. [PDF]

Front Oncol
Qin W, Fei X, Shi R, Zhou Y, Tang J, Liu Y, Zhu Y, Suo L, Liao W.   +8 more
europepmc   +1 more source

Tumor Plasticity and Microenvironmental Crosstalk as Drivers of Metastasis and Therapy Resistance

MedComm, Volume 7, Issue 8, August 2026.
The graphical abstract is a schematic illustration of the bidirectional crosstalk between tumor plasticity and the tumor microenvironment (TME) in driving metastasis and therapy resistance. Tumor‐intrinsic factors such as genetic mutations and epigenetic reprogramming enable dynamic transitions between epithelial, mesenchymal, and cancer stem cell ...
Gunjan Dagar, Manisha Dagar, Ashna Gupta, Anju Surendranath, Suraja Kumar Das, Mohd Umar Rehmani, Mukesh Tanwar, Sameer Mirza, Muzafar A. Macha, Ammira S. Al‐Shabeeb Akil, Shahab Uddin, Mayank Singh, Ajaz A. Bhat   +12 more
wiley   +1 more source