Results 71 to 80 of about 6,009 (196)
Mycosis fungoides with CD20 expression: report of two cases and review of the literature [PDF]
Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/107359/1/cup12299 ...
Arai +27 more
core +1 more source
Zusammenfassung Hintergrund und Zielsetzung Während Brentuximab vedotin (BV) oder Strahlentherapie (RTx) gängige Behandlungsoptionen für CD30‐positive kutane T‐Zell‐Lymphome (CTCL) sind, wurde über die Wirksamkeit und Verträglichkeit ihrer gleichzeitigen oder aufeinanderfolgenden Anwendung nur selten berichtet.
Patrick Schummer +10 more
wiley +1 more source
Effect of Bexarotene on Platelet Activation and Apoptosis
Background/Aims: The retinoid X receptor (RXRs) stimulator Bexarotene ((4-[1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydro-2-naphthyl)ethynyl] benzoic acid) is used for the treatment of several malignancies.
Hang Cao +4 more
doaj +1 more source
Bexaroteno e a sua aplicabilidade no tratamento do Alzheimer [PDF]
Monografia realizada no âmbito da unidade de Estágio Curricular do Mestrado Integrado em Ciências Farmacêuticas, apresentada à Faculdade de Farmácia da Universidade de CoimbraO bexaroteno, um agonista seletivo dos recetores retinóides X (RXR), foi ...
Teixeira, Ana Rita Pinheiro
core
Chemotherapy‐induced peripheral neuropathy (CIPN) remains a major clinical challenge, with central sensitization considered an important pathological mechanism in its occurrence and persistence. This review focuses on spinal astrocytes and microglia, systematically summarizing the pathological mechanisms of spinal glial cells involved in CIPN caused by
Long Gu, Song Cao, Yonghuai Feng
wiley +1 more source
Identification of Bexarotene as a PPARγ Antagonist with HDX
The retinoid x receptors (RXRs) are the pharmacological target of Bexarotene, an antineoplastic agent indicated for the treatment of cutaneous T cell lymphoma (CTCL).
David P. Marciano +3 more
doaj +1 more source
RNA-sequencing reveals transcriptional up-regulation of Trem2 in response to bexarotene treatment
We have recently demonstrated that short term bexarotene treatment of APP/PS1 mice significantly improves their cognitive performance. While there were no changes in plaque load, or insoluble Aβ levels in brain, biochemical analysis strongly suggested ...
Iliya Lefterov +5 more
doaj +1 more source
Successful Multimodal Therapeutic Approach for CD30‐positive Folliculotropic Mycosis Fungoides
JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Chiara L. Blomen +5 more
wiley +1 more source
Myeloid‐derived suppressor cells (MDSCs) are key contributors to cancer immunotherapy failure and major targets in new therapeutic strategies. We highlight therapeutic approaches to counteract their immunosuppressive functions and discuss recent efforts to optimize drug delivery for controlling MDSCs, focusing on resiquimod as a representative drug ...
Yanying He, Yoon Yeo
wiley +1 more source
ABSTRACT Background and Aims Acne vulgaris is a frequent skin disorder, affecting a large part of the population worldwide, and strongly influencing not only the physical but also the mental aspects of health. The choice of therapy for acne vulgaris is a very difficult one because the multifactorial causality of the disease and interindividual ...
Mobina Tajdari +5 more
wiley +1 more source

