Results 191 to 200 of about 63,274 (284)

ID3 deficiency alters chromatin accessibility at DSB sites and enhances vulnerability to HDAC inhibition

International Journal of Cancer, Volume 158, Issue 12, Page 3173-3186, 15 June 2026.
What's new? Errors in DNA double‐strand break (DSB) repair can lead to mutations, chromosomal instability, and ultimately cancer. Inhibitor of DNA‐binding 3 (ID3), a transcriptional repressor, is crucial to promoting DSB repair and helping maintain genome stability. Here, the authors investigated ID3 regulation of DNA repair via chromatin accessibility
Giuditta Della Corte, Hossam Eldesouky, Julia Puchan, Sercan Öz, Elena Everatt, Ashish Goyal, Gianluca Sigismondo, Udo Oppermann, Christoph Plass, Dieter Weichenhan, Ali Bakr   +10 more
wiley   +1 more source

Genome-wide analysis of bHLH transcription factor family reveals their involvement in kernel development and biotic stress responses in Chinese chestnut. [PDF]

Front Plant Sci
Li R, Huang L, Huang X, Liao J, Wei X, Li J, Zeng G, Shi Z, Zhang J, Zhao Z.   +9 more
europepmc   +1 more source

RsTTG1, a WD40 Protein, Interacts with the bHLH Transcription Factor RsTT8 to Regulate Anthocyanin and Proanthocyanidin Biosynthesis in Raphanus sativus. [PDF]

Int J Mol Sci, 2022
Lim SH, Kim DH, Lee JY.
europepmc   +1 more source

Bibliometric Analysis of Cubebenes and Related Sesquiterpenes: Natural Occurrence, Biosynthesis, Pharmacological Activities, and In‐Silico‐Based Future Therapeutic Potential

eFood, Volume 7, Issue 3, June 2026.
Cubebene‐related sesquiterpenes, found across diverse biological sources, exhibit promising pharmacological activities, including anti‐inflammatory, neuroprotective, and anticancer effects. This review highlights their molecular diversity, ADME profiles, and predicted multitarget interactions, underscoring their therapeutic relevance and potential in ...
Khadija Boualam, Ahmet B. Ortaakarsu, Sohaib Khatib, Mohamed A. Farag, Mansour Sobeh   +4 more
wiley   +1 more source

Integrated analysis of genome, metabolome, and transcriptome reveals a bHLH transcription factor potentially regulating the accumulation of flavonoids involved in carrot resistance to Alternaria leaf blight. [PDF]

PLoS One
Koutouan CE, Ramaroson ML, Ghaziri AE, Ogé L, Kebieche A, Baltenweck R, Claudel P, Hugueney P, Suel A, Huet S, Voisine L, Briard M, Helesbeux JJ, Hamama L, Le Clerc V, Geoffriau E.   +15 more
europepmc   +1 more source

Genome-Wide Identification and Expression Analysis of the bHLH Transcription Factor Family and Its Response to Abiotic Stress in Mongolian Oak (Quercus mongolica). [PDF]

Curr Issues Mol Biol, 2023
Zhan H, Liu H, Ai W, Han X, Wang Y, Lu X.   +5 more
europepmc   +1 more source

Aspartame Increases the Risk of Pancreatic Ductal Adenocarcinoma

eFood, Volume 7, Issue 3, June 2026.
Aspartame (APM) is a widely used artificial sweetener associated with various health concerns, including potential links to diabetes, cardiovascular diseases, and an increased risk of cancer. A comprehensive approach incorporating data mining, machine learning, network toxicology, molecular docking, molecular dynamics simulations, and clinical sample ...
Jumin Xie, Wei Fang, Zean Song, Zhang Yu, Ying Zhu, Shaoping Liu   +5 more
wiley   +1 more source

[Expression of Concern] Podoplanin‑mediated TGF‑β‑induced epithelial-mesen-chymal transition and its correlation with bHLH transcription factor DEC in TE‑11 cells. [PDF]

Int J Oncol
Wu Y, Liu Q, Yan X, Kato Y, Tanaka M, Inokuchi S, Yoshizawa T, Morohashi S, Kijima H.   +8 more
europepmc   +1 more source

The bHLH transcription factor ASCL1 promotes differentiation of endocrine cells in the stomach and is regulated by Notch signaling.

Am J Physiol Gastrointest Liver Physiol, 2023
Hibdon ES, Keeley TM, Merchant JL, Samuelson LC.   +3 more
europepmc   +1 more source

Genome-Wide Identification of bHLH Transcription Factor Family in Malus sieversii and Functional Exploration of MsbHLH155.1 Gene under Valsa Canker Infection. [PDF]

Plants (Basel), 2023
Jia S, Liu X, Wen X, Waheed A, Ding Y, Kahar G, Li X, Zhang D.   +7 more
europepmc   +1 more source