Linear signaling in the Toll-Dorsal pathway of Drosophila: activated Pelle kinase specifies all threshold outputs of gene expression while the bHLH protein Twist specifies a subset [PDF]
, 2002 Differential activation of the Toll receptor leads to the formation of a broad Dorsal nuclear gradient that specifies at least three patterning thresholds of gene activity along the dorsoventral axis of precellular embryos.
Levine, Michael, Stathopoulos, Angelike
core
The HY5-PIF regulatory module coordinates light and temperature control of photosynthetic gene transcription [PDF]
, 2014 The ability to interpret daily and seasonal alterations in light and temperature signals is essential for plant survival. This is particularly important during seedling establishment when the phytochrome photoreceptors activate photosynthetic pigment ...
A Alboresi +88 more
core +5 more sources
The histone H3K4 demethylase JARID1A directly interacts with haematopoietic transcription factor GATA1 in erythroid cells through its second PHD domain [PDF]
, 2020 Chromatin remodelling and transcription factors play important roles in lineage commitment and development through control of gene expression. Activation of selected lineage-specific genes and repression of alternative lineage-affiliated genes results in
Biasutto, Antonio J +4 more
core +1 more source
Context dependence of proneural bHLH proteins [PDF]
, 2008 A key point of neural development is the commitment of progenitor cells to a specific neural fate. In all animals studied, proneural proteins — transcription factors of the basic helix-loop-helix (bHLH) family — are central to this process.
Jarman, Andrew P., Powell, Lynn M.
core +1 more source
Evolutionary and comparative analysis of MYB and bHLH plant transcription factors [PDF]
The Plant Journal, 2011 SummaryThe expansion of gene families encoding regulatory proteins is typically associated with the increase in complexity characteristic of multi‐cellular organisms. The MYB and basic helix‐loop‐helix (bHLH) families provide excellent examples of how gene duplication and divergence within particular groups of transcription factors are associated with,
Antje, Feller +3 more
openaire +2 more sources
XASH genes promote neurogenesis in Xenopus embryos [PDF]
, 1994 Neural development in Drosophila is promoted by a family of basic helix-loop-helix (bHLH) transcription factors encoded within the Achaete Scute-Complex (AS-C).
Anderson, David +4 more
core
The T-cell oncogene Tal2 is a Target of PU.1 and upregulated during osteoclastogenesis [PDF]
, 2013 Transcription factors play a crucial role in regulating differentiation processes during human life and are important in disease. The basic helix-loop-helix transcription factors Tal1 and Lyl1 play a major role in the regulation of gene expression in the
Courtial, Nadine +5 more
core +2 more sources
Transcription factors and molecular markers revealed asymmetric contributions between allotetraploid Upland cotton and its two diploid ancestors [PDF]
, 2020 Three Gossypium species have been used to breed cotton as they vary in their fiber production and resistance to stresses. Transcription factors (TFs) mostly are present in different copies or isoforms by which they conduct their regulation.
Do Amaral Santos, Milena +8 more
core +2 more sources
Development of neuroendocrine lineages requires the bHLH–PAS transcription factor SIM1 [PDF]
Genes & Development, 1998 The bHLH–PAS transcription factor SIM1 is expressed during the development of the hypothalamic–pituitary axis in three hypothalamic nuclei: the paraventricular nucleus (PVN), the anterior periventricular nucleus (aPV), and the supraoptic nucleus (SON).
J L, Michaud +3 more
openaire +2 more sources
Transcriptome pathways unique to dehydration tolerant relatives of modern wheat [PDF]
, 2009 Among abiotic stressors, drought is a major factor responsible for dramatic yield loss in agriculture. In order to reveal differences in global expression profiles of drought tolerant and sensitive wild emmer wheat genotypes, a previously deployed shock ...
AN Olsen +53 more
core +1 more source