Glycoprotein E (gE) specified by bovine herpesvirus type 5 (BHV-5) enables trans-neuronal virus spread and neurovirulence without being a structural component of enveloped virions [PDF]
Bovine herpesvirus 5 (BHV-5) is a neurovirulent alpha-herpesvirus that causes fatal encephalitis in calves. We previously demonstrated that deletion of a glycine-rich epitope in the gE ectodomain dramatically reduced BHV-5 neurovirulence. To investigate the role of gE cytoplasmic tail sequences in the neuropathogenesis of BHV-5 in rabbits, we ...
Al-Mubarak, A. +5 more
openaire +3 more sources
Detection of Felis catus Gammaherpesvirus 1 in Cats, but not Dogs, in Türkiye: Prevalence and Risk Factors. [PDF]
The current study was carried out to determine prevalence of Felis catus gammaherpesvirus 1 (FcaGHV1) in Turkish domestic cats and dogs and to investigate potential risk factors that are associated with the detection of FcaGHV1. FcaGHV1‐specific DNA was detected in 4 (7.4%, 95% confidence interval 0.4–14.4) of the 54 feline blood samples by TaqMan real‐
Şevik M.
europepmc +2 more sources
EXTRATOS VEGETAIS (Nicotiana glauca e Chrysanthemum vulgaris) EM UMA VACINA CONTRA O HERPESVÍRUS BOVINO TIPO 5 (BHV-5) [PDF]
Este trabalho analisa o efeito da adição do extrato das folhas de Nicotiana glauca e Chrysanthemum vulgaris em vacina inativada contra Herpesvírus bovino tipo 5 (BHV-5) sobre a resposta imune humoral em bovinos vacinados.
OTTO FELDENS +3 more
doaj +7 more sources
Bovine Herpesvirus 5 (BHV-5) Us9 Is Essential for BHV-5 Neuropathogenesis [PDF]
ABSTRACTBovine herpesvirus 5 (BHV-5) is a neurovirulent alphaherpesvirus that causes fatal encephalitis in calves. In a rabbit model, the virus invades the central nervous system (CNS) anterogradely from the olfactory mucosa following intranasal infection.
S I, Chowdhury +5 more
openaire +2 more sources
A Glycine-Rich Bovine Herpesvirus 5 (BHV-5) gE-Specific Epitope within the Ectodomain Is Important for BHV-5 Neurovirulence [PDF]
ABSTRACTThe bovine herpesvirus 5 (BHV-5) gE ectodomain contains a glycine-rich epitope coding region (gE5 epitope), residues 204 to 218, that is significantly different from the corresponding gE region of BHV-1. Deletion of the gE epitope significantly reduced the neurovirulence of BHV-5 in rabbits.
A, Al-Mubarak, Y, Zhou, S I, Chowdhury
openaire +2 more sources
Pathogenesis of meningoencephalitis in rabbits by bovine herpesvirus type-5 (BHV-5) [PDF]
This article describes the main aspects of bovine herpesvirus type-5 (BHV-5) neurologic infection and disease in rabbits, a candidate animal model for studying BHV-5 neuropathogenesis. Intranasal inoculation of weanling rabbits with a Brazilian BHV-5 isolate produced neurological disease and death in 78.8% (26/33) of the animals.
Silva, Adriana M. da +6 more
openaire +4 more sources
Replicação e excreção viral durante a infecção aguda e após a reativação da latência induzida por dexametasona em bezerros inoculados com os herpesvírus bovinos tipo 1 (BHV-1) e 5 (BHV-5) [PDF]
Nesse estudo, comparou-se a eficiência de estabelecimento e reativação da infecção latente pelos herpesvírus bovinos tipos 1 e 5 (BHV-1 e 5) em bezerros. Bezerros inoculados pela via intranasal com uma amostra de BHV-1 (SV-265, n=6) ou BHV-5 (SV-507, n=6)
Fernanda Silveira Flores Vogel +7 more
doaj +1 more source
Bovine respiratory disease (BRD) is the costliest complex disease affecting the cattle industry worldwide, with significant economic losses. BRD pathogenesis involves several interactions between microorganisms, such as bacteria and viruses, and ...
Abdou Nagy +6 more
doaj +1 more source
Spread of bovine herpesvirus type 5 (BHV-5) in the rabbit brain after intranasal inoculation [PDF]
Following intranasal inoculation of wild-type BHV-5 in rabbits, we studied the sequential transneuronal passage of the virus in the CNS by immunocytochemistry, histopathology, and virus isolation. At 4 and 6 days postinfection (d.p.i.), rabbits had no or mild neurological signs, and virus was isolated only from the olfactory bulbs.
B J, Lee +3 more
openaire +2 more sources
A four year longitudinal sero-epidemiological study of bovine herpesvirus type-1 (BHV-1) in adult cattle in 107 unvaccinated herds in south west England [PDF]
Background: Bovine herpesvirus type-1 (BHV-1) is an important pathogen of cattle that presents with a variety of clinical signs, including the upper respiratory tract infection infectious bovine rhinotracheitis (IBR). A seroepidemiological study of BHV-
Ramírez Villaescusa, Ana +21 more
core +1 more source

