Results 41 to 50 of about 4,321,960 (262)

Aborder la mort à l'école primaire [PDF]

, 2014
La mort est un sujet tabou dans notre société actuelle et celle-ci s’est éloignée de notre quotidien. Cependant, celle-ci peut surgir à n’importe quel moment et de manière imprévisible.
Inversin, Philippe, Matthey, Vanina
core  

Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells

FEBS Letters, EarlyView.
Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López, Özge Yilmaz Ardicli, Mübeccel Akdis   +2 more
wiley   +1 more source

Balansert lederskap

Magma, 2020
Denne artikkelen diskuterer hvordan man kan kombinere vertikalt og horisontalt lederskap effektivt i prosjekter, altså hvordan lederskapet i prosjektet kan skifte mellom teammedlemmer og den formelt utpekte prosjektlederen avhengig av situasjonens krav.
Anne Live Vaagaasar, Ralf Müller
doaj   +1 more source

covsim: An R Package for Simulating Non-Normal Data for Structural Equation Models Using Copulas

Journal of Statistical Software, 2022
In factor analysis and structural equation modeling non-normal data simulation is traditionally performed by specifying univariate skewness and kurtosis together with the target covariance matrix.
Steffen Grønneberg, Njål Foldnes, Katerina M. Marcoulides   +2 more
doaj   +1 more source

Sexualaufklärung an Oberwalliser Schulen: wie setzen die SIPE-Mitarbeitenden die Sexualaufklärung während der obligatorischen Schulzeit im Oberwallis um? [PDF]

, 2017
Die vorliegende Bachelorarbeit befasst sich mit der Thematik der Sexualaufklärung. Es wird der Frage nachgegangen, wie die Sexualaufklärung von den SIPE-Mitarbeitenden während den obligatorischen Schuljahren im Oberwallis durchgeführt wird.
Andenmatten, Melanie, Christen, Ursula
core  

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Venous wall graft in the eyelid reconstruction: observations drawn from 64 cases

Dermatology Reports, 2022
The aim of this report is to illustrate the venous wall graft and to present the observations drawn from a large series of eyelid reconstructions performed with this method.
Cesare Barbera, Roberto Manzoni, Lucio Dodaro, Monica Ferraro, Pella Paolo   +4 more
doaj   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Impact of Management Support on Business Intelligence Adoption: Illustrative Case Study Testing Different Managerial Strategies

Acta Informatica Pragensia
Business intelligence (BI) is a crucial tool for organizations to gain a competitive advantage on the market. BI encompasses collection, analysis and utilization of data to enhance decision-making and drive organizational innovation.
Jakub Andar, Petra Kasparova
doaj   +1 more source