Results 71 to 80 of about 4,321,960 (262)

ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan, Yan Jiang, Yuxuan Yong, Tianshuo Zhang, Niannian Zhang, Qianqian Zeng, Xue Gong, Li Meng, Fangfang Bi, Yongmin Liu   +9 more
wiley   +1 more source

Clinical Significance of Therapeutic Drug Level Monitoring for Mycophenolate in Patients with Extra‐Renal Systemic Lupus Erythematosus – A Systematic Review & Meta‐analysis

Arthritis Care &Research, Accepted Article.
Background Clinical response to Mycophenolic acid (MPA) is highly heterogeneous; thus, therapeutic drug monitoring (TDM) may help improve treatment efficacy. This systematic review and meta‐analysis examined therapeutic ranges for MPA levels associated with better outcomes and safety in patients with SLE, particularly those with extra‐renal ...
Zahraa Qamhieh, Dalia Sriwi, Callie Saric, Tripti Singh, Christie M. Bartels, Shivani Garg   +5 more
wiley   +1 more source

Revisiting Stability Criteria in Ball‐Milled High‐Entropy Alloys: Do Hume–Rothery and Thermodynamic Rules Equally Apply?

Advanced Engineering Materials, Volume 27, Issue 6, March 2025.
The stability criteria affecting the formation of high‐entropy alloys, particularly focusing in supersaturated solid solutions produced by mechanical alloying, are analyzed. Criteria based on Hume–Rothery rules are distinguished from those derived from thermodynamic relations. The formers are generally applicable to mechanically alloyed samples.
Javier S. Blázquez, Alejandro F. Manchón‐Gordón, Antonio Vidal‐Crespo, Rafael Caballero‐Flores, Jhon J. Ipus, Clara F. Conde   +5 more
wiley   +1 more source

Enabling Digital Continuity in Virtual Manufacturing for Eco‐Efficiency Assessment of Lightweight Structures by Means of a Domain‐Specific Structural Mechanics Language: Requirements, Idea and Proof of Concept

Advanced Engineering Materials, EarlyView.
This article presents a solver‐agnostic domain‐specific language (DSL) for computational structural mechanics that strengthens interoperability in virtual product development. Using a hierarchical data model, the DSL enables seamless exchange between diverse simulation tools and numerical methods.
Martin Rädel, Andreas Schuster, Felix Schoenitz, Jean Lefèvre   +3 more
wiley   +1 more source

Antecedents of Patient Loyalty: Exploring Mediating and Moderating Paradigms in Public Hospitals

Patient Preference and Adherence
Abid Hussain,1 Shahida Kanwel,2 Sania Khan,3 Wadi B Alonazi,4 Azam Malik,3 Ali Ahmed Khan5 1School of Nursing, Shandong Xiehe University, Jinan, 250109, People’s Republic of China; 2School of Management, Jiangsu University, Zhenjiang, Jiangsu, 212013 ...
Hussain A, Kanwel S, Khan S, Alonazi WB, Malik A, Khan AA   +5 more
doaj  

Styrer og bærekraft: Norske børsnoterte selskap møter forventninger med kontroll heller enn strategi

Magma
Formålet med artikkelen er å identifisere hvordan styrer oppfatter sin rolle for å møte bærekrafts-forventninger. Vi gjennomførte digitale tekstanalyser av ESG-rapporteringen til alle selskap ved Oslo børs som ble ESG-rangert av Refinitiv i perioden ...
Janicke Rasmussen, Jovana Karajanov, Jan Ketil Arnulf   +2 more
doaj   +1 more source

Bis[bis(trimethylsilyl)cyclopentadienyl](chloro)uranium(III) bis(2,6-dimethylphenylisocyanide)

Acta Crystallographica Section C Crystal Structure Communications, 1989
[U(C 11 H 21 Si 2 ) 2 Cl] (C 9 H 9 N) 2 cristallise dans P2 1 /n avec a=16,000, b=22,806 et c=13,093 A, β=92,85 o , Z=4; affinement jusqu'a R=0,031.
Zalkin, A., Beshouri, S.M.
openaire   +2 more sources

Elinvar Materials: Recent Progress and Challenges

Advanced Engineering Materials, EarlyView.
Elinvar materials, exhibiting temperature‐invariant elastic modulus, are critical for precision instruments and emerging technologies. This article reviews recent progress in the field, with a focus on the anomalous thermoelastic behavior observed in key material systems.
Wenjie Li, Yang Ren
wiley   +1 more source

PBF‐LB/M of Ti‐6Al‐4V: High‐Pressure Solution Treatment and Aging for Applications in a Sustainable Aerospace

Advanced Engineering Materials, EarlyView.
Additive manufacturing (AM) allows great geometric freedom for lightweight components. As parts are progressively optimized exploiting potentials in AM leading in smaller material cross sections, high pressure solution treating and aging (STA) treatments show an enormous potential for strongly improving material properties.
Mika León Altmann, Andre Danzig, Freerk Syassen, Rainer Fechte‐Heinen, Anastasiya Toenjes   +4 more
wiley   +1 more source

Simulation of Hydrogen Isotopes Accumulation Processes in Materials in the Presence of Chemical Traps

Eurasian Chemico-Technological Journal, 2019
The accumulation of hydrogen inside a solids occurs in traps of a different nature. The following things are known in addition to finding hydrogen in interstitial sites: dislocation mechanisms of hydrogen storage, micropores and microcracks, sorption on ...
T.V. Kulsartov, Zh.A. Zaurbekova, Ye.V. Chikhray, M.T. Gabdullin   +3 more
doaj   +1 more source