Results 91 to 100 of about 523,087 (393)
Advanced Functional Materials, EarlyView.Hyaluronic acid‐dopamine‐based intra‐crosslinked microsphere including cisplatin (HPC MS) is fabricated by spray‐drying and calcium/iron ions are introduced for interparticle crosslinking. Designed microsphere‐aggregated hydrogel (MAH) system including cisplatin/CaO2/FeSO4 can provide apoptosis/calcicoptosis/ferroptosis‐mediated chemo/cascade ...
ChaeRim Hwang +6 more
wiley +1 more source
Exploitation of a pH-sensitive hydrogel for CO2 detection [PDF]
, 2003 In this paper is described how hydrogel is exploited as sensor material for the \ud detection of carbon dioxide (CO2). A pH-sensitive hydrogel disc, which swells and deswells in response to pH changes, was clamped between a pressure sensor membrane and a
Berg, A. van den +3 more
core +1 more source
Augmenting the Calvin-Benson-Bassham cycle by a synthetic malyl-CoA-glycerate carbon fixation pathway. [PDF]
, 2018 The Calvin-Benson-Bassham (CBB) cycle is presumably evolved for optimal synthesis of C3 sugars, but not for the production of C2 metabolite acetyl-CoA.
Chuang, Derrick S +4 more
core +1 more source
Disrupting Hypoxia-Induced Bicarbonate Transport Acidifies Tumor Cells and Suppresses Tumor Growth.
Cancer Research, 2016 Tumor hypoxia is associated clinically with therapeutic resistance and poor patient outcomes. One feature of tumor hypoxia is activated expression of carbonic anhydrase IX (CA9), a regulator of pH and tumor growth.
A. McIntyre +13 more
semanticscholar +1 more source
Intraoral Drug Delivery: Bridging the Gap Between Academic Research and Industrial Innovations
Advanced Functional Materials, EarlyView.Intraoral drug delivery offers a promising route for systemic and localized therapies, yet challenges such as enzymatic degradation, limited permeability, and microbial interactions hinder efficacy. This figure highlights innovative strategies—mucoadhesive materials, enzyme inhibitors, and permeation enhancers—to overcome these barriers.
Soheil Haddadzadegan +4 more
wiley +1 more source
Integrative signaling networks of membrane guanylate cyclases: Biochemistry and physiology
Frontiers in Molecular Neuroscience, 2016 This monograph presents a historical perspective of cornerstone developments on the biochemistry and physiology of mammalian membrane guanylate cyclases (MGCs), highlighting contributions made by the authors and their collaborators.
Rameshwar K Sharma +2 more
doaj +1 more source
Goblet Cell Hyperplasia Requires High Bicarbonate Transport To Support Mucin Release
Scientific Reports, 2016 Goblet cell hyperplasia, a feature of asthma and other respiratory diseases, is driven by the Th-2 cytokines IL-4 and IL-13. In human bronchial epithelial cells, we find that IL-4 induces the expression of many genes coding for ion channels and ...
G. Gorrieri +16 more
semanticscholar +1 more source
Advanced Functional Materials, EarlyView.Cu‐based catalysts as a cornerstone in advancing sustainable energy technologies are fully reviewed in this manuscript, highlighting their potential in photo‐ and electrocatalysis. It includes metallic copper, copper oxides, copper sulfides, copper halide perovskites, copper‐based metal–organic frameworks (MOFs), and covalent organic frameworks (COFs),
Jéssica C. de Almeida +16 more
wiley +1 more source
tlpA gene expression is required for arginine and bicarbonate chemotaxis in Helicobacter pylori
Biological Research, 2011 About half of the human population is infected with Helicobacter pylori, a bacterium causing gastritis, peptic ulcer and progression to gastric cancer. Chemotaxis and flagellar motility are required for colonization and persistence of H.
Oscar A Cerda +5 more
doaj
Carbonic Anhydrases and Metabolism
Metabolites, 2018 Although the role of carbonic anhydrases (CAs, EC 4.2.1.1) in metabolism is well-established, pharmacological applications of this phenomenon started to be considered only recently.
Claudiu T. Supuran
doaj +1 more source