Results 131 to 140 of about 175 (164)

Continuous purification of a parvovirus using two aqueous two‐phase extraction steps

Biotechnology Progress, EarlyView.
Abstract Aqueous two‐phase systems (ATPS) are a liquid–liquid extraction method that offers low‐cost, continuous‐adaptable virus purification. A two‐step ATPS using polyethylene glycol (PEG) and sodium citrate that recovered 66% of infectious porcine parvovirus with 2.0 logs of protein removal and 1.0 logs of DNA removal in batch has now been run ...
Natalie M. Nold, Sheridan Waldack, Grace James, Trisha Colling, Lynn Manchester, Taravat Sarvari, Amanda Bekkala, Seth A. Kriz, Madison Baldwin, Emily Agustin‐Mazariegos, Michael J. Betenbaugh, Caryn L. Heldt   +11 more
wiley   +1 more source

Novel molecular mechanisms of immune evasion in hepatocellular carcinoma: NSUN2‐mediated increase of SOAT2 RNA methylation

Cancer Communications, EarlyView.
Abstract Background Hepatocellular carcinoma (HCC) is a deadly malignancy known for its ability to evade immune surveillance. NOP2/Sun RNA methyltransferase family member 2 (NSUN2), an RNA methyltransferase involved in carcinogenesis, has been associated with immune evasion and energy metabolism reprogramming.
Jinhua Jiang, Feng Liu, Dan Cui, Caixia Xu, Jiachang Chi, Tinghua Yan, Fang Guo   +6 more
wiley   +1 more source

First Steps toward the Design of Peptides that Influence the Intracellular Palmitoylation Machinery

ChemBioChem, EarlyView.
Herein, DC peptides consisting of the cell‐penetrating peptide sC18* and a Asp–His–His–Cys (DHHC) motif derived from human ZDHHC palmitoyltransferase are highlighted. DC peptides demonstrate high cellular internalization into various cellular models, exert cytotoxic effects against cancerous cells, and alter the function and localization of known ...
Katharina Stillger, Eric Platz‐Baudin, Florian Friedland, Melina Ruppel, Coco‐Louisa Sticker, Anne Bodenhausen, Erik Noetzel, Ines Neundorf   +7 more
wiley   +1 more source

Effect of Trimethylamine‐N‐Oxide (TMAO) and Sorbitol on the Catalytic Activity of Candida boidinii Formate Dehydrogenase

ChemCatChem, EarlyView.
The effects of the osmolytes TMAO and sorbitol on the catalytic activity of Candida boidinii formate dehydrogenase are investigated using computational and experimental studies. The osmolytes exert different effects on the inter‐domain fluctuations, solvation, and active site dynamics of the enzyme as well as on the substrate residence times.
Julio A. Perez‐Erviti, Yasser Almeida‐Hernández, Joel Mieres‐Perez, Nicolas Gajardo‐Parra, Roland Winter, Christoph Held, Gabriele Sadowski, Elsa Sanchez‐Garcia   +7 more
wiley   +1 more source

Catalytic CO2 Conversion and H2/Syngas Production via Thermal, Plasma, and Membrane Processes

ChemCatChem, EarlyView.
In this review article, the recent progress of CO2 conversion and H2/syngas production via thermo‐catalytic, plasma‐assisted catalytic, and membrane‐assisted catalytic processes is covered. The reaction mechanism of each process is illustrated in detail based on the reaction category.
Xingyuan Gao, Zhuoying Zeng, Wei Lu, Xunxin Su, Juntian Mao, Shuxian Qiu, Sibudjing Kawi   +6 more
wiley   +1 more source

Insights into CO2 Hydrogenation to DME: In Situ DRIFTS Study of Reaction over Cu/ZSM‐5 Catalyst

Chemical Engineering &Technology, EarlyView.
This manuscript explores the intricate mechanisms of CO2 hydrogenation to MeOH and DME. We detail the reaction pathway, emphasizing the formation of key intermediates. The application of in situ DRIFTS is highlighted as a powerful tool for monitoring surface species and understanding catalytic processes.
Samira Ebrahimian, Chandan Kundu, Adrian Chun Minh Loy, Sankar Bhattacharya   +3 more
wiley   +1 more source

Novel Catalyst Layer Design with In Situ Constructed Cross‐Linked Porous Network Toward High‐Performance Proton Exchange Membrane Water Electrolysis

ChemElectroChem, EarlyView.
This work develops an in situ pore‐forming strategy to construct cross‐linked porous catalyst layers (PCL) for proton exchange membrane water electrolysis. The PCL exhibits 2.1times the electrochemical active area of conventional catalyst layers, achieving 3.8 A cm−2@1.9 V (exceeding U.S.
Ziang Wang, Zhaoping Shi, Yuqing Cheng, Ming Yang, Jinsheng Li, Zhao Jin, Meiling Xiao, Changpeng Liu, Wei Xing   +8 more
wiley   +1 more source

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Bicarbonate

Emergency Medicine Clinics of North America, 1986
Bicarbonate is a laboratory value of considerable importance in emergency medicine. It is essential in the diagnosis of acid-base disorders, but must be interpreted in the context of a number of other parameters, including electrolytes, arterial blood gases, and renal function.
D, Jehle, F, Harchelroad
openaire   +2 more sources

Bicarbonate, Not 'CO2'

Archives of Internal Medicine, 1983
Medical students, house officers, and practitioners continue to find acid-base metabolism difficult to understand. Part of that difficulty stems from terminology that is confusing and often misleading. One problem has been that the exact laboratory methods for measuring the various factors used in the evaluation of acid-base disorders have had undue ...
Howard B. Garfinkel, Nelson A. Gelfman
openaire   +3 more sources

Extracorporeal bicarbonate space after bicarbonate or a bicarbonate-carbonate mixture in acidotic dogs

Journal of Applied Physiology, 1989
The effects of sodium bicarbonate and a bicarbonate-carbonate mixture on expired CO2 and the volume of distribution of bicarbonate were studied in eight anesthetized, paralyzed, and ventilated dogs made acidotic with HCl (5 mmol/kg) infused over 90 min.
G. F. Filley, Joseph I. Shapiro, N. B. Kindig, D. S. Sherrill   +3 more
openaire   +3 more sources