Results 51 to 60 of about 3,975 (165)

A possible case of bictegravir-associated severe unconjugated hyperbilirubinemia

AIDS Research and Therapy, 2023
Background Bictegravir (BIC) co-formulated with emtricitabine (FTC) and tenofovir alafenamide (TAF) is approved by Federal Food and Drug Administration in 2018 for both treatment-naïve and experienced persons living with HIV (PLWH).
Kanak Parmar, Poemlarp Mekraksakit, Kenneth Nugent, Jacob Nichols   +3 more
doaj   +1 more source

Pharmacokinetic drug interactions of integrase strand transfer inhibitors

Current Research in Pharmacology and Drug Discovery, 2021
The integrase strand transfer inhibitor (INSTI)-containing regimens are currently considered as the first-line treatment of human immunodeficiency virus (HIV) infection.
Chi-Hua Lu, Edward M. Bednarczyk, Linda M. Catanzaro, Alyssa Shon, Jia-Chen Xu, Qing Ma   +5 more
doaj   +1 more source

Characteristics and management of low‐level viraemia in people living with HIV in a resource‐limited setting: A multicentre retrospective study in Greece

HIV Medicine, Volume 27, Issue 10, Page 1663-1669, October 2026.
Abstract Objectives Low‐level viraemia (LLV) persists in some people living with HIV despite antiretroviral therapy, raising concerns about virologic failure. We assessed the characteristics, management and outcomes of LLV in Greece, where next‐generation sequencing, therapeutic drug monitoring and electronic adherence monitoring are unavailable ...
Lydia Leonidou, Giota Lourida, Konstantinos Protopapas, Charalampos D. Moschopoulos, Dimitrios Zoulas, Charisis Totsikas, Dimitrios Basoulis, Elpida Mastrogianni, Apostolos Beloukas, Maria Lagadinou, Markos Marangos, Vasileios Papastamopoulos, Antonios Papadopoulos, Mina Psichogiou   +13 more
wiley   +1 more source

Triple therapy with Bictegravir in HIV-positive subjects: experience in the Mestre hospital [PDF]

, 2023
openBictegravir è un inibitore dell'integrasi di seconda generazione utilizzato per il trattamento dell'infezione da HIV-1 in soggetti adulti sotto forma di associazione a dose fissa Bictegravir/Emtricitabina/Tenofovir Alafenamide, approvato per l ...
MOZZON, STEFANO
core  

Material deprivation and its correlates in treatment‐naïve migrants with HIV with rapid access to B/F/TAF at no cost: A sub‐study of the ASAP cohort

HIV Medicine, Volume 27, Issue 10, Page 1698-1709, October 2026.
Abstract Objectives Material deprivation (MD), the inability to afford essentials, is linked with poorer HIV clinical outcomes. In Canada, migrants living with HIV are a growing group, yet little is known about their experience of MD, especially early in treatment. This study examined the prevalence, nature, sociodemographic and clinical correlates and
Moustafa Laymouna, Kim Engler, David Lessard, Melchior Belin, Serge Vicente, Dominic Chu, Sean Yaphe, Joseph Cox, Nadine Kronfli, Jean‐Pierre Routy, Joel Ishak, Alexandra Hamel, Marina Klein, Alexandra de Pokomandy, Cecilia T. Costiniuk, Bertrand Lebouché   +15 more
wiley   +1 more source

Placental transfer of the integrase strand inhibitors cabotegravir and bictegravir in the ex-vivo human cotyledon perfusion model

, 2020
International audienceData on placental transfer is lacking for the recent HIV integrase inhibitors, bictegravir and cabotegravir, although their future use in pregnancy is to be expected. The objective of this study was to determine their transplacental
Laurent Mandelbrot, Lê, Minh Patrick, Pencolé, Lucile, Gilles Peytavin, Bouchet-Crivat, Florian, Peytavin, Gilles, Florian Bouchet-Crivat, Duro, Dominique, Lucile Pencolé, Dominique Duro, Mandelbrot, Laurent, Minh P. Lê   +11 more
core   +1 more source

Sex differences in discontinuations due to side effects of second-generation integrase strand transfer inhibitors: a systematic review and meta-analysisResearch in context

EClinicalMedicine
Summary: Background: Dolutegravir and bictegravir are frequently prescribed second-generation integrase strand transfer inhibitors. Although sex and gender influence drug pharmacokinetics, little is known about the differences in side effects ...
Zhou Fang, Tetiana Povshedna, Rowan Patterson, Erin Ready, Helene C.F. Cote, Melanie C.M. Murray, Elizabeth M. King   +6 more
doaj   +1 more source

4% 5‐Fluorouracil Cream for Actinic Keratoses: First Report of Efficacy and Tolerability in a Person Living With Human Immunodeficiency Virus Infection

Clinical Case Reports, Volume 14, Issue 9, September 2026.
ABSTRACT Actinic keratosis (AK) is a common premalignant skin condition associated with chronic ultraviolet exposure and an increased risk of progression to cutaneous squamous cell carcinoma (cSCC). Its prevalence rises with age and is influenced by multiple factors, including fair skin phototype and immunosuppression.
Gloria Hoxhallari, Aurelio Portincasa, Nicola Fini, Vincenzo Verdura, Liberato Roberto Cecchino, Fedele Lembo, Sergio Lo Caputo, Domenico Bonamonte, Caterina Foti, Francesco Drago, Giulia Ciccarese   +10 more
wiley   +1 more source

Inhibition of Adipose Tissue Beiging by HIV Integrase Inhibitors, Dolutegravir and Bictegravir, Is Associated with Adipocyte Hypertrophy, Hypoxia, Elevated Fibrosis, and Insulin Resistance in Simian Adipose Tissue and Human Adipocytes

Cells, 2022
For people living with HIV, treatment with integrase-strand-transfer-inhibitors (INSTIs) can promote adipose tissue (AT) gain. We previously demonstrated that INSTIs can induce hypertrophy and fibrosis in AT of macaques and humans.
Kenza Ngono Ayissi, Jennifer Gorwood, Laura Le Pelletier, Christine Bourgeois, Carine Beaupère, Martine Auclair, Roberta Foresti, Roberto Motterlini, Michael Atlan, Aurélie Barrail-Tran, Roger Le Grand, Delphine Desjardins, Bruno Fève, Olivier Lambotte, Jacqueline Capeau, Véronique Béréziat, Claire Lagathu   +16 more
doaj   +1 more source

Evolution of ART Medication Adherence Support and Monitoring Across IeDEA Sites: Results From Three Waves of Consortium‐Wide Site Assessment Surveys, 2017, 2020 and 2023

Journal of the International AIDS Society, Volume 29, Issue 9, September 2026.
ABSTRACT Introduction Since 2013, global HIV treatment guidelines have included recommendations for medication adherence support and monitoring for people on antiretroviral therapy (ART). We examined the implementation of recommended strategies for adherence support and monitoring for adults with HIV through serial cross‐sectional structured surveys ...
Ellen Brazier, Francesca Odhiambo, Jessie K. Edwards, Lauren Zalla, Charles Kasozi, Eugene Messou, Chantel Schreuder, Romanee Chaiwarith, María Fernanda Rodríguez, Irene Ayakaka, Marcel Zannou, Aimee Freeman, Peter Vanes Ebasone, Dina Muktiarti, Aggrey Semeere, Vohith Khol, Ephrem Mensah, Carina Cesar, Frank Tanser, Edwin Sang, Cuong Duy Do, Armel Poda, Annabelle Niyongabo, Yanink Caro Vega, Jonathan Arthur Colasanti, Idiovino Rafael, Patricia Lelo, Gad Murenzi, Denis Nash, the International Epidemiology Databases to Evaluate AIDS (IeDEA)   +29 more
wiley   +1 more source