Persistent cell-associated HIV-1 RNA in virally suppressed individuals on INSTI-based ART
Journal of Virus EradicationIntegrase strand transfer inhibitors (INSTIs) are the cornerstone of modern antiretroviral therapy (ART), achieving durable plasma HIV-1 suppression in most people living with HIV (PLWH).
John Zaunders +2 more
exaly +4 more sources
Drugs in Context, 2023 Background: Metabolic effects of integrase strand transfer inhibitors (INSTIs) have been reported. The FDA Adverse Event Reporting System (FAERS) is a publicly available database that captures spontaneously reported adverse events.
Milena M Murray +2 more
doaj +2 more sources
Efficacy and metabolic outcomes of switching from an INSTI-based triple-drug regimen to dolutegravir/lamivudine in treatment-experienced HIV-1-infected patients: a 48-week real-world study [PDF]
Annals of MedicineBackground Real-world data on switching from INSTI-based triple therapy to DTG/3TC in the Chinese population are lacking.Methods This retrospective study included 214 treatment-experienced patients with HIV from Chongqing Public Health Medical Center ...
Wei Zhang +3 more
doaj +2 more sources
Health-related quality of life in people living with HIV on first-line INSTI versus those switched from EFV to INSTI: a cross-sectional study from four cities in China [PDF]
BMC Infectious DiseasesBackground With the widespread use of integrase strand transfer inhibitors (INSTIs) among people living with HIV (PLWH) in China, their impact on health-related quality of life (HRQOL) requires urgent evaluation. This study aimed to compare HRQOL between
Hanlu Jia +9 more
doaj +2 more sources
Фармакокинетика и Фармакодинамика, 2022 GIZh-298 is a new derivative of 4-phenylpyrrolidone with anticonvulsant and nootropic effects. A selective and sensitive HPLC-MS technique for the quantitative determination of GIZh-298 in rat blood plasma has been developed and validated.
P. O. Bochkov +5 more
doaj +1 more source
Real-World Assessment of Weight Change in African American Females and Hispanics with HIV-1 After Initiating Integrase Strand-Transfer Inhibitors or Protease Inhibitors [PDF]
Journal of Health Economics and Outcomes Research, 2022 **Background:** Studies have shown an increase in weight among people living with HIV (PLWH) who initiated integrase strand transfer inhibitors (INSTI).
Yen-Wen Chen +3 more
doaj +2 more sources
Application of lactic acid bacteria producing antifungal substance and carboxylesterase on whole crop rice silage with different dry matter [PDF]
Animal Bioscience, 2021 Objective This study was conducted to investigate effects of antifungal substance and carboxylesterase-producing inoculant on fermentation indices and rumen degradation kinetics of whole crop rice (WCR) silage ensiled at different dry matter (DM ...
Seong Shin Lee +7 more
doaj +1 more source
EFFECT OF DIETARY ARGININE SUPPLEMENTATION ON SOME HORMONES AND ITS RELATION TO PERFORMANCE OF SILVER MONTAZAH CHICKEN. 2- THE EFFECT ON LAYING DURATION. [PDF]
Egyptian Poultry Science, 2016 This experiment was conducted in Inshas Poultry Research Station, Ministry of Agricultural, Egypt, A total number of 420 hens and 105 cocks from Silver Montazah chickens (SM) (Egyptian local strain) flock were used to investigate the effect of dietary ...
M Sabry +4 more
doaj +1 more source
PLoS ONE, 2023 BackgroundAntiretroviral therapy (ART) decreases perinatal HIV transmission, but concerns exist regarding maternal and infant safety. We compared the incidence of congenital malformations and other adverse outcomes in pregnancies exposed to integrase ...
Christiana Smith +12 more
doaj +1 more source
Perception Regarding Hazards of Plastics Usage and Effectiveness of Plastic Ban in Rural Tamil Nadu
National Journal of Community Medicine, 2020 Background: Plastics have become part of our modern lives and the amount of plastics produced in this decade equals the amount produced in the last century.
Raja Danasekaran +4 more
doaj +1 more source