Results 101 to 110 of about 56,899 (289)

Management of Cardiovascular Health Issues in Turner Syndrome: Expert Insights and Expanded Recommendations From the 2024 Guideline Development Team

American Journal of Medical Genetics Part C: Seminars in Medical Genetics, EarlyView.
ABSTRACT Turner syndrome (TS) is frequently complicated by congenital heart disease (CHD). While left‐sided lesions such as bicuspid aortic valve (BAV) and coarctation of the aorta are the most common structural heart lesions in TS, other anomalies, such as aortic arch malformations, hypoplastic left heart syndrome (HLHS), persistent left superior vena
Katya de Groote, Sheetal R. Patel, Kristian Havmand Mortensen, Isabel Witvrouwen, Anthonie Duijnhouwer, Nicole M. Brown, Jasmine Grewal, Kathryn C. Chatfield, Aaron T. Dorfman, Siddharth K. Prakash   +9 more
wiley   +1 more source

Bicuspid Aortic Valve in Children and Young Adults for Cardiologists and Cardiac Surgeons: State-of-the-Art of Literature Review

Journal of Cardiovascular Development and Disease
Bicuspid aortic valve disease is the most prevalent congenital heart disease, affecting up to 2% of the general population. The presentation of symptoms may vary based on the patient’s anatomy of fusion, with transthoracic echocardiography being the ...
Francesco Nappi, Sanjeet Singh Avtaar Singh, Paolo M. de Siena   +2 more
doaj   +1 more source

Visualizing Turner Syndrome

American Journal of Medical Genetics Part C: Seminars in Medical Genetics, EarlyView.
ABSTRACT Turner syndrome (TS) continues to present a diagnostic challenge to healthcare professionals. The diagnostic challenges associated with TS result in delayed treatment and clinical care. Here we provide an update of the physical appearance of girls and women with TS by presenting clinical photographs and detailed clinical descriptions of 25 ...
Kirstine Stochholm, Astrid Bruun Rasmussen, Anne Skakkebæk   +2 more
wiley   +1 more source

Point on the Aortic Bicuspid Valve

Life, 2022
Background—Bicuspid aortic valve (BAV) disease is the most prevalent congenital heart disease in the world. Knowledge about its subtypes origin, development, and evolution is poor despite the frequency and the potential gravity of this condition.
Chloé Bernard, Marie Catherine Morgant, David Guillier, Nicolas Cheynel, Olivier Bouchot   +4 more
doaj   +1 more source

The Impact of Karyotype on Congenital Heart Diseases in Turner Syndrome: A Systematic Review and Meta‐Analysis

American Journal of Medical Genetics Part C: Seminars in Medical Genetics, EarlyView.
ABSTRACT It is evident that Turner syndrome (TS) impacts almost all developmental stages of the fetal heart with congenital heart disease (CHD) being seen in 23%–50% of individuals. Although the spectrum of CHDs in TS is well‐established, with left‐sided lesions predominating, the influence of specific karyotypes on the prevalence and types of CHDs ...
Francisco Álvarez‐Nava, Melissa L. Crenshaw, Ivonne Bedei, Marisol Soto, Andréa T. Maciel‐Guerra, Anne Skakkebæk   +5 more
wiley   +1 more source

Use of a targeted, combinatorial next-generation sequencing approach for the study of bicuspid aortic valve [PDF]

, 2014
BACKGROUND: Bicuspid aortic valve (BAV) is the most common type of congenital heart disease with a population prevalence of 1-2%. While BAV is known to be highly heritable, mutations in single genes (such as GATA5 and NOTCH1) have been reported in few ...
David Newsom, Don Corsmeier, Elizabeth M Bonachea, Gloria Zender, Kim L McBride, Peter White, Sara Fitzgerald-Butt, Vidu Garg   +7 more
core   +2 more sources

Fostamatinib and the risk of acute aortic dissection in immune thrombocytopenia

British Journal of Clinical Pharmacology, EarlyView.
Immune thrombocytopenia (ITP) is a rare autoimmune disorder characterized by platelet destruction. While most patients respond to first‐ or second‐line therapies, a small subset is multirefractory. Fostamatinib, an oral spleen tyrosine kinase (SYK) inhibitor, is a therapeutic option in these cases.
Paul Dalmas, Alexis Theron, Rita Badaoui, Stéphane Zaffran, Rayid Mchinda, Joelle Micallef, Nicolas Schleinitz, Mikael Ebbo   +7 more
wiley   +1 more source

Aortendilatation und Funktion des linken Ventrikels bei bikuspider Aortenklappe [PDF]

, 2015
Einleitung: Die bikuspide Aortenklappe (BAK) ist mit einer Prävalenz von 0.5-2% der häufigste angeborene Herzfehler. Die Dilatation der Aorta ascendens ist eine häufige Begleiterkrankung der BAK, die im schlimmsten Fall zum plötzlichen Herztod bei ...
Fina, Fabienne, Frangi, Jana
core   +1 more source

Coronary Ectasia and ST Elevation Myocardial Infarction Patients: Does Atherosclerosis Influence Periprocedural Management and Long‐Term Prognosis?

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background Coronary artery ectasia (CAE) influences procedural outcomes in the context of ST‐elevation myocardial infarction (STEMI); however, its relationship with atherosclerotic coronary artery disease (ACAD) remains unclear. Aims This study aimed to compare clinical and procedural characteristics, as well as outcomes, in patients with ...
Victorine Fraichot, Jeanne Varlot, Florian Eggenspieler, Nassima Djaballah, Pierre Adrien Metzdorf, Edoardo Camenzind, Batric Popovic   +6 more
wiley   +1 more source

Thoracic Aortic Aneurysm Growth Rates and Predicting Factors: A Systematic Review and Meta‐Analysis

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background Thoracic aortic aneurysm (TAA) is an indolent, potentially fatal disease, which progresses at variable rates that are influenced by pathogenesis and patient characteristics.
Matthew Henry, Carlos A. Campello Jorge, Pieter A.J. van Bakel, Heather A. Knauer, Mark MacEachern, Joost A. van Herwaarden, Gisela Teixidó‐Tura, Arturo Evangelista, Richmond W. Jeremy, C. A. Figueroa, Himanshu J. Patel, Marion Hofmann Bowman, Kim Eagle, Nicholas S. Burris   +13 more
doaj   +1 more source