Results 81 to 90 of about 15,320 (206)

Differentiating the Clinical and Variant Spectrum of Hardikar Syndrome From Other MED12 ‐Related Developmental Disorders

American Journal of Medical Genetics Part A, Volume 200, Issue 7, Page 1619-1650, July 2026.
ABSTRACT The rare X‐linked female‐restricted Hardikar syndrome (HDKR, OMIM # 301068) is characterized by multiple congenital anomalies including orofacial clefts, gastrointestinal, genitourinary, and cardiac anomalies, but cognitive and neurobehavioral development is rarely impaired.
Tinne Warmoeskerken, Miel Theunis, Kris Van den Bogaert, Koenraad Devriendt, Jeroen Breckpot   +4 more
wiley   +1 more source

Pre‐Sport Cardiac Evaluation in Children: Detection of Risks Other Than Sudden Cardiac Death

Annals of Noninvasive Electrocardiology, Volume 31, Issue 4, July 2026.
In children who want to play sports, is a cardiac evaluation necessary only for sudden cardiac death? ABSTRACT Objective Sudden deaths may occur in children and adolescents due to unexpected cardiac problems during sports. This study aimed to screen for abnormalities that may lead to future morbidity in addition to the risk of sudden death and to ...
Mehmet Öncül, Abdulgani Gülyüz
wiley   +1 more source

Bicuspid Aortic Valve Outcomes

, 2017
BACKGROUND: Bicuspid aortic valve is the most common CHD. Its association with early valvular dysfunction, endocarditis, thoracic aorta dilatation, and aortic dissection is well established. OBJECTIVE: The aim of this study was to assess the incidence
Agapito, A, Branco, LM, Galrinho, A, Oliveira, JA, Rodrigues, I, Abreu, J, Sousa, L, Cruz Ferreira, R, Timóteo, AT, Aguiar Rosa, S   +9 more
core   +1 more source

Endothelial Notch1 Is Required for Proper Development of the Semilunar Valves and Cardiac Outflow Tract

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2016
BackgroundCongenital heart disease is the most common type of birth defect, affecting ≈2% of the population. Malformations involving the cardiac outflow tract and semilunar valves account for >50% of these cases predominantly because of a bicuspid aortic
Sara N. Koenig, Kevin Bosse, Uddalak Majumdar, Elizabeth M. Bonachea, Freddy Radtke, Vidu Garg   +5 more
doaj   +1 more source

Evaluation of the Utility of Baseline Echocardiogram in Patients With Standard Risk Precursor B‐Lymphoblastic Leukemia

Pediatric Blood &Cancer, Volume 73, Issue 6, June 2026.
ABSTRACT Background A routine baseline echocardiogram is often obtained prior to anthracycline administration in children with cancer. The utility of baseline echocardiogram is unclear in patients with standard risk B‐cell acute lymphoblastic leukemia (SR B‐ALL) as their anthracycline cumulative dose is low.
Ziyad Alrajhi, Alice Pozza, Luc Mertens, Adam Paul Yan, Sarah Alexander   +4 more
wiley   +1 more source

Acute Finger Ischemia Evaluated With Point‐Of‐Care‐Ultrasound and Diagnosed With Concurrent Polycythemia Vera, Antiphospholipid Syndrome, and Tobacco Use

Clinical Case Reports, Volume 14, Issue 6, June 2026.
We present a case of digital ischemia investigated and localized using point‐of‐care ultrasound (POCUS), in a patient that was subsrquently diagnosed with antiphospholipid syndrome and polycythemia vera concurrently, in the setting of active tobacco use. ABSTRACT In patients with undifferentiated extremity ischemia, point‐of‐care ultrasound (POCUS) can
Tristan Burgess, Michael C. Larkins, Titus Chu   +2 more
wiley   +1 more source

Ventricular pressure-volume loop and other heart function metrics can elucidate etiology of failure of TAVI and interventions

REC: Interventional Cardiology (English Ed.)
Aortic valve stenosis is one of the most acute and chronic cardiovascular disease conditions. Bicuspid aortic valve is the most common congenital heart abnormality and affected individuals have a 50% chance of developing severe aortic valve ...
Zahra Keshavarz-Motamed
doaj   +1 more source

Association of 3‐Day Postoperative Blood Glucose Variability With All‐Cause Mortality in ICU Patients After Surgical Repair of Acute Type A Aortic Dissection: A Retrospective Cohort Study Using the MIMIC‐IV Database

Clinical Cardiology, Volume 49, Issue 6, June 2026.
Among 201 ICU patients undergoing open repair for Stanford type A aortic dissection (TAAD), higher 3‐day postoperative glucose coefficient of variation (%CV) was positively associated with ICU and in‐hospital mortality. %CV outperformed mean and median glucose and improved predictive performance when combined with the APACHE II score.
Tianyi Gu, Yingying Zhang, Gang Li, Zhonghao Pang, Jingjing Huang, Zhou Zhou, Shengjie Chen   +6 more
wiley   +1 more source

Bicuspid aortic valve: Unlocking the morphogenetic puzzle

, 2016
Although bicuspid aortic valve is the most common congenital abnormality, it is perhaps erroneous to consider this disease one clinical entity. Rather, it may be useful to consider it a cluster of diseases incorporating different phenotypes, etiologies ...
Khandheria, Bijoy K, Carerj, Scipione, Jain, Renuka, Longobardo, Luca, Zito, Concetta   +4 more
core   +1 more source

Disruption of Notch1 and Gata5 in Mice Leads to Congenital Aortic Valve Disease

JACC: Basic to Translational Science
Summary: Here, we describe Notch1;Gata5 compound mutant mice as a novel mouse model of highly penetrant congenital aortic valve disease displaying bicuspid aortic valve and progressive aortic valve stenosis.
Jun Yasuhara, MD, PhD, Mona Aljuhani, PhD, Talita Z. Choudhury, PhD, Anupama Rao, PhD, Sara Conroy, PhD, Yukie Ueyama, DVM, Stephanie LaHaye, PhD, Karlee Schultz, MS, Emily M. Cameron, MS, Sathiya N. Manivannan, PhD, Uddalak Majumdar, PhD, Vidu Garg, MD   +11 more
doaj   +1 more source