Results 81 to 90 of about 21,536 (218)

Surgical treatment of bicuspid aortic valve disease [PDF]

Journal of Cardiothoracic Surgery, 2013
Background Congenital bicuspid aortic valve (BAV) – one of the most frequent cardiovascular lesions, with prevalence up to 2.4%. About a half of them need the surgical treatment throughout life. Methods 1217 patients with BAV were treated in the Institute during 2003 2012. There were 902 (74.1%) males.
Kravchenko, Ivan, Kravchenko, VI, Sytar, LL, Pantas, OV, Dykuha, SO, Atamanyuk, MY, Knyshov, GV   +6 more
openaire   +1 more source

Interventional therapies for chronic heart failure: An overview of recent developments

ESC Heart Failure, Volume 12, Issue 2, Page 1081-1094, April 2025.
Abstract Heart failure (HF), the final manifestation of most cardiovascular diseases, has become a major global health concern, affecting millions of individuals. Despite basic drug treatments, patients present with high morbidity and mortality rates. However, recent advancements in interventional therapy have shown promising results in improving the ...
Bingchen Guo, Si Shi, Yutong Guo, Jie Xiong, Bo Wang, Zengxiang Dong, Dianyu Gao, Yingfeng Tu   +7 more
wiley   +1 more source

Thoracic Aortic Aneurysm Growth Rates and Predicting Factors: A Systematic Review and Meta‐Analysis

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background Thoracic aortic aneurysm (TAA) is an indolent, potentially fatal disease, which progresses at variable rates that are influenced by pathogenesis and patient characteristics.
Matthew Henry, Carlos A. Campello Jorge, Pieter A.J. van Bakel, Heather A. Knauer, Mark MacEachern, Joost A. van Herwaarden, Gisela Teixidó‐Tura, Arturo Evangelista, Richmond W. Jeremy, C. A. Figueroa, Himanshu J. Patel, Marion Hofmann Bowman, Kim Eagle, Nicholas S. Burris   +13 more
doaj   +1 more source

Use of a targeted, combinatorial next-generation sequencing approach for the study of bicuspid aortic valve [PDF]

, 2014
BACKGROUND: Bicuspid aortic valve (BAV) is the most common type of congenital heart disease with a population prevalence of 1-2%. While BAV is known to be highly heritable, mutations in single genes (such as GATA5 and NOTCH1) have been reported in few ...
David Newsom, Don Corsmeier, Elizabeth M Bonachea, Gloria Zender, Kim L McBride, Peter White, Sara Fitzgerald-Butt, Vidu Garg   +7 more
core   +2 more sources

Increased calcification by erythrophagocytosis in aortic valvular interstitial cells

ESC Heart Failure, Volume 12, Issue 2, Page 1469-1473, April 2025.
Abstract Background Calcific aortic valve disease (CAVD) progresses over time to severe aortic stenosis and eventually heart failure. Recent evidence indicates that intraleaflet haemorrhage (ILH) strongly promotes CAVD progression. However, it remains poorly understood how it mechanistically contributes to valvular calcification.
Zihan Qin, Magnus Bäck, Anders Franco‐Cereceda, Sven‐Christian Pawelzik   +3 more
wiley   +1 more source

Transcatheter Treatment of Bicuspid Aortic Valve Stenosis: From Observational Studies to Randomized Clinical Trials

Structural Heart
Bicuspid aortic valve (BAV) disease is the most common congenital heart abnormality, which affects up to 2% of the population and significantly increases the lifetime risk of aortic stenosis and the need for valve replacement. While surgical aortic valve
Daryoush Samim, MD, Matthias Siepe, MD, Peter Jüni, MD, Aakriti Gupta, MD, Hasan Jilaihawi, MD, Michael A. Borger, MD-PhD, Raj R. Makkar, MD, Martin B. Leon, MD, Stephan Windecker, MD   +8 more
doaj   +1 more source

Yield of Whole Genome Sequencing for Pathogenic Single Nucleotide Variants in Congenital Heart Disease: A Systematic Review and Meta‐Analysis

Prenatal Diagnosis, EarlyView.
ABSTRACT Objective This systematic review and meta‐analysis aimed to assess the diagnostic yield of pathogenic or likely pathogenic (P/LP) single nucleotide variants (SNVs) using whole genome sequencing (WGS) in congenital heart disease (CHD). Methods A systematic search of three databases (2000–2024) was conducted, and two reviewers independently ...
Hiba J. Mustafa, Parisa Najjariasl, Faezeh Aghajani, Enaja V. Sambatur, Andrew Rodenbarger, Stephanie Guseh, Amy E. Roberts, Alireza A. Shamshirsaz   +7 more
wiley   +1 more source

Aortendilatation und Funktion des linken Ventrikels bei bikuspider Aortenklappe [PDF]

, 2015
Einleitung: Die bikuspide Aortenklappe (BAK) ist mit einer Prävalenz von 0.5-2% der häufigste angeborene Herzfehler. Die Dilatation der Aorta ascendens ist eine häufige Begleiterkrankung der BAK, die im schlimmsten Fall zum plötzlichen Herztod bei ...
Fina, Fabienne, Frangi, Jana
core   +1 more source

Expanding the Phenotype of TAB2‐Related Syndrome: The First Case With Cleft Palate and Insights Into Palatal Development

American Journal of Medical Genetics Part A, EarlyView.
Alberto De Rosa, Silvia Kalantari, Marta Carboni, Antonella Casella, Elisa Giorgio, Antonia Apicella, Alessia Claudia Codazzi, Fabio Sirchia   +7 more
wiley   +1 more source

Sex‐based differences in outcomes between male and female patients with bicuspid aortic stenosis following transcatheter aortic valve replacement: A meta‐analysis

Precision Medical Sciences, EarlyView.
Central illustration: Sex‐based differences in outcomes between male and female patients with bicuspid aortic stenosis following transcatheter aortic valve replacement. Abstract Bicuspid aortic valve (BAV) is a common congenital anomaly leading to early aortic stenosis.
Muhammad Huzaifa Ahmed Khan, Muneeb Khawar, Asad Ullah Farooq, Azooba Khalid, Syed Muhammad Ahsan, M. Hamza Naseer Awan, Muhammad Soban Nisar, Asim Elahi, Muhammad Aqib Faizan, Iqra Shahid, Abdullah Munir Ahmed, Faseeh Haider, Rejina Chhetri   +12 more
wiley   +1 more source