Results 71 to 80 of about 21,536 (218)

Balloon‐Expandable Versus Self‐Expanding Valves in Low‐Flow, Low‐Gradient Aortic Stenosis: Does Valve Type Matter?

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background The optimal choice between balloon‐expandable (BE) and self‐expanding (SE) transcatheter heart valves (THVs) in patients with low‐flow low‐gradient aortic stenosis (LFLG AS) undergoing transcatheter aortic valve replacement (TAVR) remains unclear.
Nav Warraich, James A. Brown, Abbad Sultan, Dustin Kliner, Derek Serna‐Gallegos, Catalin Toma, Amber Makani, Irsa Hasan, Takuya Ogami, Jianhui Zhu, Ibrahim Sultan   +10 more
wiley   +1 more source

Experimental evidence of the genetic hypothesis on the etiology of bicuspid aortic valve aortopathy in the hamster model

Frontiers in Cardiovascular Medicine, 2022
Bicuspid aortopathy occurs in approximately 50% of patients with bicuspid aortic valve (BAV), the most prevalent congenital cardiac malformation. Although different molecular players and etiological factors (genetic and hemodynamic) have been suggested ...
María Teresa Soto-Navarrete, María Teresa Soto-Navarrete, Bárbara Pozo-Vilumbrales, Bárbara Pozo-Vilumbrales, Miguel Ángel López-Unzu, Miguel Ángel López-Unzu, Miguel Ángel López-Unzu, Carmen Rueda-Martínez, M. Carmen Fernández, M. Carmen Fernández, M. Carmen Fernández, Ana Carmen Durán, Ana Carmen Durán, Francisco Javier Pavón-Morón, Francisco Javier Pavón-Morón, Francisco Javier Pavón-Morón, Jorge Rodríguez-Capitán, Jorge Rodríguez-Capitán, Jorge Rodríguez-Capitán, Borja Fernández, Borja Fernández, Borja Fernández   +21 more
doaj   +1 more source

Fate of the Aortic Arch Following Surgery on Aortic Root and Ascending Aorta in Bicuspid Aortic Valve. [PDF]

, 2018
BACKGROUND: Recent guidelines support more aggressive surgery for aneurysms of the ascending aorta and root in patients with bicuspid aortic valve. However, the fate of the arch after surgery of the root and ascending aorta is unknown.
Bilkhu, R, Child, A, Edsell, M, Jahangiri, M, Liban, B, Nowell, J, Phillips, S, Sharma, R, Soppa, G, Theodoropoulos, P, Tome, M, Youssefi, P   +11 more
core   +1 more source

Novel Phenotypes in Bicuspid Aortic Valve Disease

, 2011
Bicuspid aortic valve (BAV) is the most common congenital abnormality of the human heart, affecting approximately 1-2% of the general population (Williams, 2006). It is widely accepted that BAV is a very heterogeneous disease and that the different phenotypes of BAV disease may be caused by unique pathogenetic mechanisms.
Girdauskas, Evaldas, A., Michael, Kuntze, Thomas   +2 more
openaire   +4 more sources

Annular Ellipticity and Sizing Strategy in Transcatheter Aortic Valve Implantation: Independent or Combined Risk Patterns?

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background Elliptical annular anatomy has been considered a risk factor for adverse outcomes after TAVI, particularly paravalvular leakage (PVL). Prosthesis oversizing is thought to improve sealing, but the interaction between annular shape and sizing strategy remains unclear.
Emre Polat, Lisa Müller, Lena Schemet, Sarah Friedrich Welz, Mohamed Amer, Evaldas Girdauskas, Tamer Owais   +6 more
wiley   +1 more source

Rare regulatory mutations disrupt mesenchymal molecular programs driving endocardial cushion formation in bicuspid aortic valve

Nature Communications
Bicuspid aortic valve, a prevalent congenital malformation, predisposes individuals to severe complications. Although the condition exhibits substantial heritability, known protein-coding and common regulatory mutations explain a minority of cases.
Artemy Zhigulev, Andrey Buyan, Enikő Lázár, Nikita Gryzunov, Karin Lång, Raphaël Mauron, Vladimir Nozdrin, Rapolas Spalinskas, Sailendra Pradhananga, Madeleine Petersson Sjögren, Doreen Schwochow, Anders Franco-Cereceda, Joakim Lundeberg, Ivan V. Kulakovskiy, Per Eriksson, Hanna M. Björck, Pelin Sahlén   +16 more
doaj   +1 more source

Sequencing of NOTCH1, GATA5, TGFBR1 and TGFBR2genes in familial cases of bicuspid aortic valve [PDF]

, 2013
BACKGROUND: The purpose of our study was to investigate the potential contribution of germline mutations in NOTCH1, GATA5 and TGFBR1 and TGFBR2 genes in a cohort of Italian patients with familial Bicuspid Aortic Valve (BAV). METHODS: All the coding exons
Cecilia Vecoli, Ilenia Foffa, Lamia Ait Alì, Maria Grazia Andreassi, Massimiliano Mariani, Nicoletta Botto, Paola Panesi, Pierluigi Festa   +7 more
core   +1 more source

Single Centre Experience With the Balloon‐Expandable Myval Transcatheter Aortic Valve System in Patients With Bicuspid Anatomy: 1 Year Follow‐Up

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background Transcatheter aortic valve implantation (TAVI) in bicuspid aortic valve (BAV) anatomy remains challenging due to anatomical complexity and limited trial data. New‐generation balloon‐expandable valves, such as Myval, require further evaluation in this subgroup.
Balázs Magyari, Bálint Kittka, Ilona Goják, Gábor Kasza, Kristóf Schönfeld, László Botond Szapáry, Mihály Simon, Rudolf Kiss, Andrea Bertalan, Edit Várady, István Szokodi, Iván Horváth   +11 more
wiley   +1 more source

Point on the Aortic Bicuspid Valve

Life, 2022
Background—Bicuspid aortic valve (BAV) disease is the most prevalent congenital heart disease in the world. Knowledge about its subtypes origin, development, and evolution is poor despite the frequency and the potential gravity of this condition.
Chloé Bernard, Marie Catherine Morgant, David Guillier, Nicolas Cheynel, Olivier Bouchot   +4 more
doaj   +1 more source

Proximal aortic stiffening in Turner patients may be present before dilation can be detected : a segmental functional MRI study [PDF]

, 2017
Background: To study segmental structural and functional aortic properties in Turner syndrome (TS) patients. Aortic abnormalities contribute to increased morbidity and mortality of women with Turner syndrome.
Achten, Eric, Babin, Danilo, De Groote, Katya, De Schepper, Jean, Demulier, Laurent, Devos, Daniel, Rietzschel, Ernst, Segers, Patrick, Taeymans, Yvo, Van Bortel, Lucas, Westenberg, Jos J   +10 more
core   +2 more sources