Bicuspid Aortic Valve Disease: A Comprehensive Review [PDF]
Cardiology Research and Practice, 2012 Bicuspid aortic valve is the commonest congenital cardiac abnormality in the general population. This paper article will discuss our current knowledge of the anatomy, pathophysiology, genetics, and clinical aspects of bicuspid aortic valve disease.
Ify Mordi, Nikolaos Tzemos
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Bicuspid Aortic Valve Disease and Ascending Aortic Aneurysms: Gaps in Knowledge [PDF]
Cardiology Research and Practice, 2012 The bicuspid aortic valve is the most common congenital cardiac anomaly in developed nations. The abnormal bicuspid morphology of the aortic valve results in valvular dysfunction and subsequent hemodynamic derangements. However, the clinical presentation
Katie L. Losenno +2 more
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The Natural History of Bicuspid Aortic Valve Disease. [PDF]
Struct Heart, 2023 The bicuspid aortic valve (BAV) is the most common congenital heart defect with an estimated prevalence of between 0.5% and 2% in the United States, representing up to 6.5 million individuals. Most individuals with BAV will develop valvular and/or aortic complications related to their BAV.
Kusner JJ +3 more
europepmc +5 more sources
Thoracic aortopathy in Marfan syndrome overlaps with mechanisms seen in bicuspid aortic valve disease. [PDF]
Front Cardiovasc Med, 2023 Background Thoracic aortopathy is a serious complication which is more often seen in patients with Marfan syndrome (MFS) and patients with a bicuspid aortic valve (BAV) than in individuals with a tricuspid aortic valve (TAV). The identification of common
Grewal N +5 more
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Transcatheter aortic valve replacement for bicuspid aortic valve disease: does conventional surgery have a future? [PDF]
Ann Cardiothorac Surg, 2022 Bicuspid aortic valve (BAV) disease is the most common form of congenital heart valve defect. It is associated with aortic stenosis (AS), aortic insufficiency, and aortopathy.
Yeats BB +3 more
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Hemodynamic Assessment in Bicuspid Aortic Valve Disease and Aortic Dilation: New Insights From Voxel-By-Voxel Analysis of Reverse Flow, Stasis, and Energetics. [PDF]
Front Bioeng Biotechnol, 2021 Objectives: Clinical management decisions surrounding ascending aorta (AAo) dilation in bicuspid aortic valve (BAV) disease benefit from personalized predictive tools.
Geeraert P +10 more
europepmc +2 more sources
The need for comprehensive multidisciplinary programs, complex interventions, and precision medicine for bicuspid aortic valve disease. [PDF]
Ann Cardiothorac Surg, 2022 Patients with bicuspid aortic valves commonly require an intervention on their valve and/or aorta. Because of their heterogeneous presentations, recommendations for imaging surveillance and surgery timing are highly individualized.
Crawford EE +8 more
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Urinary Metabolomics Study of Patients with Bicuspid Aortic Valve Disease. [PDF]
Molecules, 2021 Bicuspid aortic valve (BAV) is the most common congenital heart defect responsible for valvular and aortic complications in affected patients. Causes and mechanisms of this pathology are still elusive and thus the lack of early detection biomarkers leads
Chessa M +7 more
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Aortic flow patterns and wall shear stress maps by 4D-flow cardiovascular magnetic resonance in the assessment of aortic dilatation in bicuspid aortic valve disease [PDF]
Journal of Cardiovascular Magnetic Resonance, 2018 BackgroundIn patients with bicuspid valve (BAV), ascending aorta (AAo) dilatation may be caused by altered flow patterns and wall shear stress (WSS). These differences may explain different aortic dilatation morphotypes.
José F. Rodríguez‐Palomares +14 more
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Aorta smooth muscle-on-a-chip reveals impaired mitochondrial dynamics as a therapeutic target for aortic aneurysm in bicuspid aortic valve disease. [PDF]
Elife, 2021 Background: Bicuspid aortic valve (BAV) is the most common congenital cardiovascular disease in general population and is frequently associated with the development of thoracic aortic aneurysm (TAA).
Abudupataer M +17 more
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