Multimodal Assessment of Vascular and Ventricular Function in Children and Adults With Bicuspid Aortic Valve Disease. [PDF]
Background: Bicuspid aortic valve (BAV), the most common congenital cardiac anomaly, has been associated with an aortopathy, increased aortic stiffness and diastolic dysfunction. The involved mechanisms and impact of age remain unclear. It was the aim of
Weismann CG+3 more
europepmc +2 more sources
Medial tunica degeneration of the ascending aortic wall is associated with specific microRNA changes in bicuspid aortic valve disease. [PDF]
Ascending aortic diameter is not an accurate parameter for surgical indication in patients with bicuspid aortic valve (BAV). Thus, the present study aimed to identify specific microRNAs (miRNAs/miRs) and their expression levels in aortic wall aneurysm ...
Pisano C+10 more
europepmc +2 more sources
Left ventricular remodelling in bicuspid aortic valve disease.
AIMS Characterization of left ventricular (LV) geometric pattern and LV mass could provide an important insight into the pathophysiological adaptations of the LV to pressure and/or volume overload in patients with bicuspid aortic valve (BAV) and ...
S. Butcher+25 more
semanticscholar +5 more sources
The prevalence of bicuspid aortic valve (BAV) disease is 0.5 - 2% of the population with a 3:1 male predominance. The genetic basis remains unknown although 9% of families have more than one affected individual.
Lee, James C. , Otto, Catherine M.
doaj +3 more sources
Transcatheter Treatment of Bicuspid Aortic Valve Disease: Imaging and Interventional Considerations [PDF]
Patients with bicuspid aortic valve disease have systematically been excluded from large randomized clinical trials investigating transcatheter aortic valve implantation (TAVI) due to their younger age, lower surgical risk and complex aortic anatomy. The
Rajiv Das, Rishi Puri
doaj +2 more sources
Differential flow improvements after valve replacements in bicuspid aortic valve disease: a cardiovascular magnetic resonance assessment [PDF]
BackgroundAbnormal aortic flow patterns in bicuspid aortic valve disease (BAV) may be partly responsible for the associated aortic dilation. Aortic valve replacement (AVR) may normalize flow patterns and potentially slow the concomitant aortic dilation ...
Malenka M. Bissell+6 more
openalex +2 more sources
Bicuspid aortic valve associated aortopathy: a genetic disease? [PDF]
The present paper briefly reviews the literature supporting the pathogenetic importance of hemodynamics in the development of bicuspid aortic valve-associated aortopathy.
Ciro Bancone+2 more
doaj +6 more sources
BACKGROUND: Thoracic aortic disease and bicuspid aortic valve (BAV) likely have a heritable component, but large population-based studies are lacking.
Jason P. Glotzbach+10 more
openalex +2 more sources
Ascending aortic aneurysm and aortic valve dysfunction in bicuspid aortic valve disease [PDF]
BACKGROUND: The relationship of aortic valve dysfunction and ascending aortic aneurysm is unclear in adults with bicuspid aortic valve disease. METHODS: We retrospectively studied 134 consecutive out-patients (98 men, 36 women aged 43+/-18years) with ...
Aydin, A.+15 more
core +5 more sources
Causes, Diagnosis, Risk Stratification and Treatment of Bicuspid Aortic Valve Disease: An Updated Review. [PDF]
The most common congenital heart disease is the bicuspid aortic valve. Understanding the pathophysiology and the altered hemodynamics is a key component for the diagnosis, risk stratification and treatment. Among others, aortic valve stenosis is the most
Sakellaropoulos S+5 more
europepmc +2 more sources