Results 81 to 90 of about 33,001 (294)

Fostamatinib and the risk of acute aortic dissection in immune thrombocytopenia

British Journal of Clinical Pharmacology, EarlyView.
Immune thrombocytopenia (ITP) is a rare autoimmune disorder characterized by platelet destruction. While most patients respond to first‐ or second‐line therapies, a small subset is multirefractory. Fostamatinib, an oral spleen tyrosine kinase (SYK) inhibitor, is a therapeutic option in these cases.
Paul Dalmas, Alexis Theron, Rita Badaoui, Stéphane Zaffran, Rayid Mchinda, Joelle Micallef, Nicolas Schleinitz, Mikael Ebbo   +7 more
wiley   +1 more source

Ascending aortic aneurysm and aortic valve dysfunction in bicuspid aortic valve disease

, 2013
BACKGROUND: The relationship of aortic valve dysfunction and ascending aortic aneurysm is unclear in adults with bicuspid aortic valve disease. METHODS: We retrospectively studied 134 consecutive out-patients (98 men, 36 women aged 43+/-18years) with ...
Aydin, A., Berger, J., Bernhardt, A., Desai, N., Detter, C., Hillebrand, M., Lorenzen, V., Meinertz, T., Mortensen, K., Reichenspurner, H., Robinson, P., Rybczynski, M., Sheikhzadeh, S., Treede, H., von Kodolitsch, Y., Willems, S.   +15 more
core   +1 more source

Sequencing of NOTCH1, GATA5, TGFBR1 and TGFBR2genes in familial cases of bicuspid aortic valve [PDF]

, 2013
BACKGROUND: The purpose of our study was to investigate the potential contribution of germline mutations in NOTCH1, GATA5 and TGFBR1 and TGFBR2 genes in a cohort of Italian patients with familial Bicuspid Aortic Valve (BAV). METHODS: All the coding exons
Cecilia Vecoli, Ilenia Foffa, Lamia Ait Alì, Maria Grazia Andreassi, Massimiliano Mariani, Nicoletta Botto, Paola Panesi, Pierluigi Festa   +7 more
core   +1 more source

Coronary Ectasia and ST Elevation Myocardial Infarction Patients: Does Atherosclerosis Influence Periprocedural Management and Long‐Term Prognosis?

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background Coronary artery ectasia (CAE) influences procedural outcomes in the context of ST‐elevation myocardial infarction (STEMI); however, its relationship with atherosclerotic coronary artery disease (ACAD) remains unclear. Aims This study aimed to compare clinical and procedural characteristics, as well as outcomes, in patients with ...
Victorine Fraichot, Jeanne Varlot, Florian Eggenspieler, Nassima Djaballah, Pierre Adrien Metzdorf, Edoardo Camenzind, Batric Popovic   +6 more
wiley   +1 more source

Study of the correlation between bicuspid aortic valve and the development of aortic dissection [PDF]

, 2017
La disección aórtica (AD) es la condición letal más comúnmente diagnosticada de la arteria aorta y consiste en el redireccionamiento del flujo sanguíneo desde el lumen de la aorta hasta la media de la pared de la aorta a través de una pequeña fisura en ...
Ruiz Jiménez, Elvira
core  

Reconstruction of the Bicuspid Aortic Valve [PDF]

Operative Techniques in Thoracic and Cardiovascular Surgery, 2007
Abicuspid aortic valve (BAV) occurs in 2% of the population and is a common reason for significant aortic regurgitation, particularly in the third and fourth decades of life.1 In these young patients, the choice of valve substitute is difficult. With a mechanical valve, the linearized risk of thromboembolic complications and anticoagulation-related ...
openaire   +2 more sources

Pulmonary Valve Morphology in Patients with Bicuspid Aortic Valves [PDF]

Pediatric Cardiology, 2018
The aortic and pulmonary valve share a common developmental origin from the embryonic arterial trunk. Bicuspid aortic valve is the most common congenital anomaly and can occur isolated as well as in association with other congenital heart disease (CHD). Data on pulmonary valve morphology in these cases are scarce.
Koenraadt, W.M.C., Bartelings, M.M., Gittenberger-de Groot, A.C., Bokenkamp, R., DeRuiter, M.C., Schalij, M.J., Jongbloed, M.R.M.   +6 more
openaire   +4 more sources

Outcomes of Fluoroscopy‐Based Asymmetric Underexpansion With the Self‐Expanding ACURATE Neo and Neo2 Valve

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background Asymmetric underexpansion of transcatheter heart valves (THVs), as observed on fluoroscopy, may influence prosthesis function or long‐term durability of transcatheter aortic valve implantation (TAVI). Aims This study aimed to evaluate the effect of stent frame asymmetry on hemodynamic performance and clinical outcomes in ACURATE neo
Daisuke Sato, Noriaki Moriyama, Hirokazu Miyashita, Yoichi Sugiyama, Tommi Vähäsilta, Teemu Laakso, Sebastian Dahlbacka, Tiina Vainikka, Juho Viikilä, Mika Laine, Mikko Jalanko   +10 more
wiley   +1 more source

Relation of Bicuspid Aortic Valve Morphology to the Dilatation Pattern of the Proximal Aorta: Focus on the Transvalvular Flow

Cardiology Research and Practice, 2012
Whether the dilatation of proximal aorta in patients with bicuspid aortic valve is secondary to hemodynamic effects related to the abnormal aortic valve or a primary manifestation of the genetic disorder remains controversial.
Evaldas Girdauskas, Kushtrim Disha, Michael-Andrew Borger, Thomas Kuntze   +3 more
doaj   +1 more source

A novel source of arterial valve cells linked to bicuspid aortic valve without raphe in mice

eLife, 2018
Abnormalities of the arterial valve leaflets, predominantly bicuspid aortic valve, are the commonest congenital malformations. Although many studies have investigated the development of the arterial valves, it has been assumed that, as with the ...
Lorriane Eley, Ahlam MS Alqahtani, Donal MacGrogan, Rachel V Richardson, Lindsay Murphy, Alejandro Salguero-Jimenez, Marcos Sintes Rodriguez San Pedro, Shindi Tiurma, Lauren McCutcheon, Adam Gilmore, José Luis de La Pompa, Bill Chaudhry, Deborah J Henderson   +12 more
doaj   +1 more source