Results 1 to 10 of about 357,794 (136)

Bicycle Urbanism, Blog 1 [PDF]

, 2015
Student blog posts from the Great VCU Bike Race ...
Becker, Matthew
core   +3 more sources

Anticancer immunity induced by a synthetic tumor-targeted CD137 agonist

Journal for ImmunoTherapy of Cancer, 2021
Background In contrast to immune checkpoint inhibitors, the use of antibodies as agonists of immune costimulatory receptors as cancer therapeutics has largely failed.
Sailaja Battula, Kristen Hurov, Johanna lahdenranta, Gemma Mudd, Punit Upadhyaya, Elizabeth Repash, Julia Kristensson, Marianna Kleyman, Jessica Kublin, Liuhong Chen, Eric Haines, Kevin McDonnell, Philip Brandish, Nicholas Keen, Rachel Dods, Rachid Lani, Katerine Van Rietschoten, Tom Stephen, Fanglei You   +18 more
doaj   +1 more source

Multivalent bicyclic peptides are an effective antiviral modality that can potently inhibit SARS-CoV-2

Nature Communications, 2023
COVID-19 has stimulated the rapid development of new antibody and small molecule therapeutics to inhibit SARS-CoV-2 infection. Here we describe a third antiviral modality that combines the drug-like advantages of both.
Katherine U. Gaynor, Marina Vaysburd, Maximilian A. J. Harman, Anna Albecka, Phillip Jeffrey, Paul Beswick, Guido Papa, Liuhong Chen, Donna Mallery, Brian McGuinness, Katerine Van Rietschoten, Steven Stanway, Paul Brear, Aleksei Lulla, Katarzyna Ciazynska, Veronica T. Chang, Jo Sharp, Megan Neary, Helen Box, Jo Herriott, Edyta Kijak, Lee Tatham, Eleanor G. Bentley, Parul Sharma, Adam Kirby, Ximeng Han, James P. Stewart, Andrew Owen, John A. G. Briggs, Marko Hyvönen, Michael J. Skynner, Leo C. James   +31 more
doaj   +1 more source

Logit and probit models explaining perceived cycling motives, barriers, and biking trip generation in Lahore, Pakistan

TeMA: Journal of Land Use, Mobility and Environment, 2021
Cycling as an attractive mode of transport is a challenge, especially in developing countries like Pakistan. Previous research on cycling in developing countries is insufficient to answer that how people can be encouraged to bike in different regions and
Izza Anwer, Houshmand Masoumi, Atif Bilal Aslam, Muhammad Asim   +3 more
doaj   +1 more source

Integrating spatial and temporal approaches for explaining bicycle crashes in high-risk areas in Antwerp (Belgium) [PDF]

, 2019
The majority of bicycle crash studies aim at determining risk factors and estimating crash risks by employing statistics. Accordingly, the goal of this paper is to evaluate bicycle-motor vehicle crashes by using spatial and temporal approaches to ...
Chang, SK Jason, De Backer, Hans, De Maeyer, Philippe, Lauwers, Dirk, Wang, Hwa-Chyi   +4 more
core   +2 more sources

DirectMX – One-Step Reconstitution of Membrane Proteins From Crude Cell Membranes Into Salipro Nanoparticles

Frontiers in Bioengineering and Biotechnology, 2020
Integral membrane proteins (IMPs) are central to many physiological processes and represent ∼60% of current drug targets. An intricate interplay with the lipid molecules in the cell membrane is known to influence the stability, structure and function of ...
Pilar Lloris-Garcerá, Stefan Klinter, Liuhong Chen, Michael J. Skynner, Robin Löving, Jens Frauenfeld   +5 more
doaj   +1 more source

How Many Cars in the City Are Too Many? Towards Finding the Optimal Modal Split for a Multi-Modal Urban Road Network

Frontiers in Future Transportation, 2021
Interactions among different modes or vehicle classes in urban road networks affect the network performance in different and complex ways. Thus, an answer to the question of “how many cars are too many for a city?” is not trivial.
Allister Loder, Allister Loder, Lea Bressan, Maria J. Wierbos, Henrik Becker, Andy Emmonds, Martin Obee, Victor L. Knoop, Monica Menendez, Kay W. Axhausen   +9 more
doaj   +1 more source

Dangerous Overtaking of Cyclists in Montréal

Safety, 2022
It is largely consented that the bicycle is a sustainable mobility alternative in the city. Despite its many benefits, cycling comprises risks of injury or death.
Andres Henao, Philippe Apparicio
doaj   +1 more source

On the influence of tyre and structural properties on the stability of bicycles [PDF]

, 2017
In recent years the Whipple Carvallo Bicycle Model has been extended to analyse high speed stability of bicycles. Various researchers have developed models taking into account the effects of front frame compliance and tyre properties, nonetheless, a ...
Doria, Alberto, Roa Melo, Sergio Daniel
core   +1 more source

Effect of suspension systems on the physiological and psychological responses to sub-maximal biking on simulated smooth and bumpy tracks [PDF]

, 2006
The aim of this study was to compare the physiological and psychological responses of cyclists riding on a hard tail bicycle and on a full suspension bicycle. Twenty males participated in two series of tests. A test rig held the front axle of the bicycle
Arthur Whittaker, Berry M., Borg G. A. V., Graves P., Ian Watt, John Titlestad, Mark Davie, McArdle W., Stanley Grant, Titlestad J., Titlestad J., Tony Fairlie-Clarke   +11 more
core   +1 more source