Results 41 to 50 of about 49,147 (254)

Renal Clearable Luminogenic Reporter for Ultrasensitive Influenza Virus Imaging and Efficient Antiviral Therapies Monitoring in Living Mice

open access: yesAdvanced Science, EarlyView.
A viral luminogenic reporter with chemiluminescence/fluorescence dual‐response and efficient renal clearance was developed for non‐invasive imaging and urinalysis of H1N1 virus protease, allowing for remote detection of H1N1 virus infections and monitoring of antiviral therapeutic efficacy in living mice.
Bankang Ruan   +9 more
wiley   +1 more source

Incorporating Bicycles into Urban Mobility: An Opportunity for Sustainable Development

open access: yesCommunications, 2017
This paper addresses the new role of bicycles as a mode of sustainable urban transport in several cities, after decades of being seen as a minor means of transport.
Carlos Lopez-Escolano   +4 more
doaj   +1 more source

On the bicycle problem

open access: yesDiscrete Applied Mathematics, 1983
AbstractWe present a counterexample to a conjecture of Shinji Masuda.
openaire   +1 more source

AI Designed Conformation Locking Peptides Target STING to Restore Diabetic Wound Healing

open access: yesAdvanced Science, EarlyView.
A generative AI pipeline identifies SCP‐1, a conformation‐locking peptide that stabilizes inactive STING. Incorporated into a dual‐responsive hydrogel for localized, MMP‐9‐triggered release, SCP‐1 suppresses inflammation, promotes reparative macrophage polarization, and accelerates diabetic wound healing.
Xinyu Li   +8 more
wiley   +1 more source

Application of Neural Networks to Analyse the Spatial Distribution of Bicycle Traffic Before, During and After the Closure of the Mill Road Bridge in Cambridgeshire, United Kingdom

open access: yesSensors
Traffic congestions due to construction and maintenance works of road infrastructure cause travel delays, unpredictability and less tolerant road users. Bicyclists are more flexible with road closures, shifting to alternative routes, public transport and
Shohel Amin
doaj   +1 more source

TRIM28‐Derived Peptide Exerts Anti‐Tumor Roles by Stabilizing Tumor Suppressive BRD7 Protein in Multiple Cancers

open access: yesAdvanced Science, EarlyView.
An α‐helical peptide, TAB12, designed to mimic the TRIM28 binding interface, competitively disrupts the TRIM28‐BRD7 interaction, thereby blocking ubiquitin‐mediated degradation of the tumor suppressor BRD7. This stabilization unleashes potent anti‐tumor effects across multiple tumor types with a favorable safety profile, offering a feasible strategy ...
Qingqing Wei   +10 more
wiley   +1 more source

Multi-Objective Routing and Categorization of Urban Network Segments for Cyclists

open access: yesApplied Sciences
This study develops a progressive navigation and guidance model for the route selection of cyclists executed in a designated area. The route selection of cyclists is modeled as a Pareto multi-objective optimization problem which is solved with the NSGA ...
Konstantinos Theodoreskos   +1 more
doaj   +1 more source

PD Controller for Bicycle Model Balancing [PDF]

open access: yesRobotica & Management, 2018
Bicycle is a conventional vehicle and it cannot self-balance. An equivalent model is required to be supplied in order to base a control structure for this under-actuated system.
Anh Khoa Vo   +6 more
doaj  

Generalized bicycles

open access: yesDiscrete Applied Mathematics, 1997
Let \(G=(V,E)\) be a graph with \(n\) vertices, and let \(M\) be a (left) modul over a principal ideal domain \(D\). Let \(W_0(M)\) and \(W_1(M)\) denote the modules of all vertex and edge weightings over \(M\), respectively. An incidence weighting \(\eta\) of \(G\) is a weighting of each incident vertex-edge pair \((v, e)\) with an element of \(D ...
Kenneth A. Berman, Yanpei Liu
openaire   +1 more source

Control for an autonomous bicycle [PDF]

open access: yesProceedings of 1995 IEEE International Conference on Robotics and Automation, 2002
The control of nonholonomic and underactuated systems with symmetry is illustrated by the problem of controlling a bicycle. We derive a controller which, using steering and rear-wheel torque, causes a model of a riderless bicycle to recover its balance from a near fall as well as converge to a time parameterized path in the ground plane.
Getz, Neil H., Marsden, J. E.
openaire   +2 more sources

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