Results 51 to 60 of about 111,060 (242)
Posture keeing property of the bicycle with twin gimbal mechanism using gyroscopic moment effect
Nihon Kikai Gakkai ronbunshu, 2017 Gyro actuator is often used for the posture control of systems which cannot be supported on a fixed ground. The gyroscopic moment makes preccesion movement of the gimbal mechanism and its effect depends on the rotating speed of the wheel.
Kazuya OGATA +2 more
doaj +1 more source
Temporal variations of bicycle demand in the Netherlands: The influence of weather on cycling [PDF]
, 2009 The variability in bicycle demand depends strongly on weather. This paper describes a ‘weather’ model that makes demand forecasting possible. The model is based on flow time-series of many years, collected at 16 cycle paths in the Dutch cities of Gouda ...
Tutert, S.I.A. +2 more
core
Dual pKa Lipid Nanoparticles for Lung‐tropic mRNA Delivery and pH‐Programmed Endosomal Escape
Advanced Science, EarlyView.Lipid nanoparticles’ bottleneck lies in low endosomal escape efficiency and liver‐dominant delivery after intravenous administration. To overcome these limitations, we present a stepwise pH‐programmed lipid nanoparticle system enabled by our newly synthesized ionizable lipid.
Seong Gi Lim +12 more
wiley +1 more source
Intended and Unintended Effects of Youth Bicycle Helmet Laws [PDF]
Over 20 states have adopted laws requiring youths to wear a helmet when riding a bicycle. We confirm previous research indicating that these laws reduced fatalities and increased helmet use, but we also show that the laws significantly reduced youth ...
Christopher S. Carpenter, Mark F. Stehr
core
, 2016 Bicycles offer effective means of exercise and are popular forms of transportation. One fault of the current use of bicycles is that the mechanical energy generated by a moving bicycle is often wasted in the form of friction and expended heat.
Alexandra N. Howell (10078837)
core +1 more source
Advanced Science, EarlyView.Two‐photon calcium imaging in behaving 5xFAD mice reveals early CA1 coding deficits before behavioral decline. Task‐related place cell activity and splitter cell trajectory coding are impaired, with reduced retrospective dominance and greater prospective weighting.
Yimei Li +8 more
wiley +1 more source
Advanced Science, EarlyView.In this work, MSN‐BO@LUT penetrates the blood‐spinal cord barrier for luteolin delivery in spinal cord injury. The nanodrug suppresses neuroinflammation and promotes functional recovery of the spinal cord. Mechanistically, luteolin targets protein arginine N‐methyltransferase (PRMT2) to decrease toll‐like receptor 4 (TLR4) methylation, thereby ...
Yixuan Wang +11 more
wiley +1 more source
Advanced Science, EarlyView.Non‐canonical amino acids (ncAAs) enhance peptide therapeutics but remain difficult to model computationally. SinCAA, a similarity‐enhanced pretraining framework, jointly optimizes contrastive learning guided by a novel conformational similarity metric with masked node reconstruction, capturing both functional relationships and chemical identity of ...
Chencheng Xu +8 more
wiley +1 more source
Arizona bicycle facilities planning & design guidelines [PDF]
, 1988 122 p ...
Governor's Arizona Bicycle Task Force. Facilities Planning Committee
core +1 more source