Results 1 to 10 of about 2,920 (220)

Phytochemical Composition of Selaginella spp. from Java Island Indonesia [PDF]

open access: yesMakara Seri Sains, 2012
For a long time, people in West Java, Indonesia have used Selaginella as a traditional cure for several ailments including fever, minor wounds, broken bones, women’s health disorders or postnatal bleeding.
Tatik Chikmawati   +2 more
doaj   +5 more sources

Biflavonoid as potential 3-chymotrypsin-like protease (3CLpro) inhibitor of SARS-Coronavirus

open access: yesResults in Chemistry, 2021
3CL protease is one of the key proteins expressed by SARS-Coronavirus-2 cell, the potential to be targeted in the discovery of antivirus during this COVID-19 pandemic.
Yustina Sri Hartini   +2 more
exaly   +3 more sources

Ginkgetin: A Promising Multitarget Agent for Diverse Diseases [PDF]

open access: yesBiomolecules
Ginkgetin (GK) is a naturally occurring biflavonoid predominantly isolated from Ginkgo biloba and has attracted increasing attention because of its broad pharmacological activities.
Zhitong Sun   +4 more
doaj   +2 more sources

Seasonal Variation of Polyphenols and Pigments in Ginkgo (Ginkgo biloba L.) Leaves: Focus on 3′,8″-Biflavones [PDF]

open access: yesPlants
Ginkgo (Ginkgo biloba L.) is a widely recognized medicinal plant, often grown as an ornamental species in parks around the world. Its leaves change color from green in spring to yellow in autumn.
Iva Jurčević Šangut, Dunja Šamec
doaj   +2 more sources

A Review on the Phytochemistry, Pharmacology, and Pharmacokinetics of Amentoflavone, a Naturally-Occurring Biflavonoid

open access: yesMolecules, 2017
Amentoflavone (C30H18O10) is a well-known biflavonoid occurring in many natural plants. This polyphenolic compound has been discovered to have some important bioactivities, including anti-inflammation, anti-oxidation, anti-diabetes, and anti-senescence ...
Sheng Yu, Hui Yan, Li Zhang
exaly   +3 more sources

Antioxidant potential of biflavonoid attenuates hyperglycemia by modulating the carbohydrate metabolic enzymes in high fat diet/streptozotocin induced diabetic rats

open access: yesRedox Report, 2020
Objectives: The present study was to isolate the biflavonoid (a bimolecular kaemferol structured molecule) and test its efficacy on oxidative stress and carbohydrate metabolic key enzymes in control and high fat diet and streptozotocin -induced diabetic ...
R Sundaram   +2 more
exaly   +2 more sources

Enhancing GSDME-induced pyroptosis through low-dose doxorubicin/biflavonoid derivative co-loaded nanodisc in hepatocellular carcinoma [PDF]

open access: yesDrug Delivery
The chemotherapeutic drug doxorubicin (DOX) has been demonstrated to trigger pyroptosis in tumor cells at exceptionally high concentrations. Nevertheless, the administration of DOX at suprapharmacological doses could cause acute off-target cytotoxicity ...
Yang Wang   +9 more
doaj   +2 more sources

Gymnosperm-specific CYP90Js enable biflavonoid biosynthesis and microbial production of amentoflavone [PDF]

open access: yesNature Communications
Biflavonoids, a unique subclass of flavonoids with superior clinical activity compared to their monomeric counterparts, offer distinct therapeutic benefits by targeting multiple pathways in neurodegenerative disorders. However, the mechanism of flavonoid
Xue-Hui Dai   +5 more
doaj   +2 more sources

Amentoflavone as an Ally in the Treatment of Cutaneous Leishmaniasis: Analysis of Its Antioxidant/Prooxidant Mechanisms

open access: yesFrontiers in Cellular and Infection Microbiology, 2021
Treatment of leishmaniasis is a challenging subject. Although available, chemotherapy is limited, presenting toxicity and adverse effects. New drugs with antileishmanial activity are being investigated, such as antiparasitic compounds derived from plants.
Yasmin Silva Rizk   +12 more
doaj   +1 more source

A Purified Biflavonoid Extract From Selaginella moellendorffii Alleviates Gout Arthritis via NLRP3/ASC/Caspase-1 Axis Suppression

open access: yesFrontiers in Pharmacology, 2021
Background: Activation of nucleotide oligomerization domain-like receptor protein 3 (NLRP3) inflammasome plays a crucial role in gout. Selaginella moellendorffii has been confirmed effective for the treatment of gout in hospital preparations. Flavonoids,
Xueyan Zhang   +7 more
doaj   +1 more source

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