Results 21 to 30 of about 2,761 (194)

Enhancing GSDME-induced pyroptosis through low-dose doxorubicin/biflavonoid derivative co-loaded nanodisc in hepatocellular carcinoma. [PDF]

Drug Deliv
Wang Y, Fu Y, Wu M, Wan H, Chen X, Ge L, Shi C, Li Y, Zeng X, Wang T.   +9 more
europepmc   +5 more sources

Correction: Amentoflavone and cancer: mechanistic insights and translational perspectives [PDF]

Frontiers in Oncology
Hiroki Hashida, Atsushi Kobayashi, Masatoshi Akagami, Tomohiro Okamoto, Hirokazu Tanaka   +4 more
doaj   +2 more sources

Gymnosperm-specific CYP90Js enable biflavonoid biosynthesis and microbial production of amentoflavone. [PDF]

Nat Commun
Dai XH, Zhu JM, Wang GY, Ren YH, Liu HL, Wang Y.   +5 more
europepmc   +3 more sources

High-performance liquid chromatography - diode array detection method validation for amentoflavone-type biflavonoids in five Encephalartos species with potential neuroprotective activity. [PDF]

Sci Rep
El-Natory ZG, Ahmed HS, Amir DE, Abdelwahab NS, Moawad A.   +4 more
europepmc   +3 more sources

Biflavonoids can Potentially Inhibit Amyloid Beta Internalization to Mitigate Its Cytotoxic Events [PDF]

Molecular Nutrition &Food Research, Volume 70, Issue 2, 29 January 2026.
Biflavonoids attenuate amyloid‐β (Aβ) induced cellular toxicity by inhibiting Aβ entry into cells. This blockade suppresses apoptosis‐related pathways, including caspase activation and nuclear lamin fragmentation, thereby promoting cellular protection and neuroprotective effects.
Md. Aminul Haque, Md. Selim Hossain, Vijay Sankar Ramasamy, Il Seon Park   +3 more
openalex   +2 more sources

<i>In Silico</i> Identification of Chiral Biflavonoids as Dual PI3Kα/mTOR Inhibitors. [PDF]

ACS Omega
Nunes Azevedo FF, Freitas de Sousa FJ, Martins Negreiro J, Vieira Carletti J, Oliveira MCF, Zanatta G.   +5 more
europepmc   +3 more sources

A Purified Biflavonoid Extract From Selaginella moellendorffii Alleviates Gout Arthritis via NLRP3/ASC/Caspase-1 Axis Suppression

Frontiers in Pharmacology, 2021
Background: Activation of nucleotide oligomerization domain-like receptor protein 3 (NLRP3) inflammasome plays a crucial role in gout. Selaginella moellendorffii has been confirmed effective for the treatment of gout in hospital preparations. Flavonoids,
Xueyan Zhang, Yingbo Liu, Guangrui Deng, Guangrui Deng, Bisheng Huang, Guoyin Kai, Keli chen, Juan Li   +7 more
doaj   +1 more source

Biflavonoids from Selaginella doederleinii as Potential Antitumor Agents for Intervention of Non-Small Cell Lung Cancer

Molecules, 2021
Four new biflavonoids (1–4) were isolated from Selaginella doederleinii together with a known biflavonoid derivative (5). Their structures contained a rare linker of individual flavones to each other by direct C-3-O-C-4′′′ bonds, and were elucidated by ...
Fenghua Kang, Sha Zhang, Dekun Chen, Jianbing Tan, Min Kuang, Jinlin Zhang, Guangyuan Zeng, Kangping Xu, Zhenxing Zou, Guishan Tan   +9 more
doaj   +1 more source

7,7″-Dimethoxyagastisflavone Inhibits Proinflammatory Cytokine Release and Inflammatory Cell Recruitment through Modulating ERα Signaling

Biomedicines, 2021
Acute systemic inflammatory diseases, including sepsis, usually result in cytokine disorder and multiple-organ failure. 7,7″-Dimethoxyagastisflavone (DMGF), a biflavonoid isolated from the needles of Taxus x media var.
Yi-Shin Wu, Chian-Ruei Chen, Yun-Ting Yeh, Han-Huei Lin, Yin-Hsuan Peng, Yu-Ling Lin   +5 more
doaj   +1 more source

(aS)-Glucosciadopitysin, a New Biflavonoid Glycoside from the Leaves of Ginkgo biloba and Osteogenic Activity of Bioflavonoids. [PDF]

Plants (Basel)
Jeong SY, Lee KH, Kim SH, Yang MH, Lee G, Kim KH.   +5 more
europepmc   +3 more sources