Results 1 to 10 of about 2,055 (112)
Alogliptin/Amentoflavone Combination Mitigates Bleomycin-Induced Lung Fibrosis: The Role of Oxidative Stress, TXNIP-Mediated Pyroptosis, and Autophagy/Apoptosis Balance [PDF]
PharmaceuticalsBackground/Objectives: Bleomycin is an antineoplastic antibiotic used in the management of various malignancies. Nevertheless, its benefits are constrained by the development of pulmonary fibrosis.
Hanan Abdelmawgoud Atia +7 more
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Amentoflavone and cancer: mechanistic insights and translational perspectives [PDF]
Frontiers in OncologyAmentoflavone (AF) is a naturally occurring biflavonoid isolated from multiple medicinal plants and widely studied for anti-inflammatory and antioxidant activities. In oncology, AF has emerged as a pleiotropic small molecule that modulates interconnected
Hiroki Hashida +4 more
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Selaginella extracts extend lifespan and mitigate oxidative stress in Caenorhabditis elegans [PDF]
Frontiers in PharmacologyIntroductionSelaginella species hold a traditional place in medicine and cosmetics, but their potential to extend lifespan and the underlying bioactive compounds remain inadequately investigated.
Xueqing Chen +15 more
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Amentoflavone Inhibits HSV-1 and ACV-Resistant Strain Infection by Suppressing Viral Early Infection
Viruses, 2019 Infection of Herpes simplex virus 1 (HSV-1) induces severe clinical disorders, such as herpes simplex encephalitis and keratitis. Acyclovir (ACV) is the current therapeutic drug against viral infection and ACV-resistant strains have gradually emerged ...
Kai Zheng, Kai Zheng, Yi-fei Wang
exaly +3 more sources
Network pharmacology and experimental study on the inhibition of glycolysis by amentoflavone in pancreatic cancer [PDF]
Discover OncologyBackgrounds Pancreatic cancer is one of the most common malignancies in the gastrointestinal system, notorious for its high malignancy and low survival rate.
Xu He +8 more
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Molecules, 2017 Amentoflavone (C30H18O10) is a well-known biflavonoid occurring in many natural plants. This polyphenolic compound has been discovered to have some important bioactivities, including anti-inflammation, anti-oxidation, anti-diabetes, and anti-senescence ...
Sheng Yu, Li Zhang, Sam Fong-Yau Li
exaly +3 more sources
Drug Delivery, 2020 Amentoflavone (AMF) is a kind of biflavonoids existing in Ginkgo biloba leaves. It has many biological activities, such as antioxidant, anti-inflammatory, anti-bacterial, antiviral, hypoglycemic, anti-tumor and inducing apoptosis. However, its solubility
Xia Zhang, Xue Feng, Luya Li
exaly +2 more sources
Amentoflavone from Selaginella tamariscina inhibits SARS-CoV-2 RNA-dependent RNA polymerase [PDF]
HeliyonThe SARS-CoV-2 pandemic caused millions of deaths due to its prominent infectivity and mortality. Although the vaccines and medicines for SARS-CoV-2 are on the market, new coronavirus variants like influenza are expected to reemerge continuously ...
Kyoung Won Youn +7 more
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Insights Into Amentoflavone: A Natural Multifunctional Biflavonoid
Frontiers in Pharmacology, 2021 Amentoflavone is an active phenolic compound isolated from Selaginella tamariscina over 40 years. Amentoflavone has been extensively recorded as a molecule which displays multifunctional biological activities.
Xifeng Xiong +8 more
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Mediators of Inflammation, 2022 Background. Amentoflavone, a natural biflavone, exerts anti-inflammation, antioxidation, and antiapoptosis effects on many diseases. However, the mechanism of amentoflavone on neuroinflammation-related diseases has not been comprehensively examined ...
Shikuo Rong +6 more
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