Results 21 to 30 of about 2,074 (130)

Amentoflavone Affects Epileptogenesis and Exerts Neuroprotective Effects by Inhibiting NLRP3 Inflammasome

Frontiers in Pharmacology, 2019
Brain inflammation is one of the main causes of epileptogenesis, a chronic process triggered by various insults, including genetic or acquired factors that enhance susceptibility to seizures. Amentoflavone, a naturally occurring biflavonoid compound that
Shikuo Rong, Ding Wan, Ding Wan, Yayun Fan, Shenhai Liu, Kuisheng Sun, Junming Huo, Peng Zhang, Xinxiao Li, Xiaoliang Xie, Feng Wang, Feng Wang, Tao Sun, Tao Sun   +13 more
doaj   +1 more source

Natural Deep Eutectic Solvent Extraction of Amentoflavone from Selaginella uncinata

Shipin gongye ke-ji, 2022
Objective: The deep eutectic solvent was used to extract the amentoflavone (AME) of Selaginella uncinata and the extraction process parameters were optimized.
Gang LI, Yongmei JIANG, Jie LEI, Feng ZHANG, Weiwei LI, Sihui LI, Chao LIU, Li LIU, Jiaqi YU, Gang WANG   +9 more
doaj   +1 more source

Isolation and Activity of Two Antibacterial Biflavonoids from Leaf Extracts of (Clusiaceae)

Natural Product Communications, 2009
The antibacterial activity of the acetone extract of Garcinia livingstonei leaves was studied using bioautography and by determining the minimum antibacterial concentration against four nosocomial pathogens.
Adamu A. Kaikabo, Babatunde B. Samuel, Jacobus N. Eloff   +2 more
doaj   +1 more source

Amentoflavone Attenuates Clostridium perfringens Gas Gangrene by Targeting Alpha-Toxin and Perfringolysin O

Frontiers in Pharmacology, 2020
Clostridium perfringens (C. perfringens) type A strains are the main cause of gas gangrene in humans and animals. Treatment of this lethal disease is limited, and the prognosis is not good.
Shui Liu, Shui Liu, Xiaofeng Yang, Xiaofeng Yang, Hong Zhang, Hong Zhang, Jian Zhang, Yonglin Zhou, Tingting Wang, Naiyu Hu, Xuming Deng, Xuming Deng, Xiaoxue Bai, Jianfeng Wang, Jianfeng Wang   +14 more
doaj   +1 more source

BIOLOGICAL ACTIVITY OF HYPERICUM PERFORATUM L. (HYPERICACEAE): A REVIEW

Фармация и фармакология (Пятигорск), 2021
Hypericum perforatum L. (St. John's wort) is a medicinal plant that has been intensivly studied by clinicians, pharmacologists, and chemists. It has resulted in the publication of both original articles and a number of, reviews devoted to the general ...
A. L. Budantsev, V. A. Prikhodko, I. V. Varganova, S. V. Okovityi   +3 more
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Viburnum stellato-tomentosum Extract Suppresses Obesity and Hyperglycemia through Regulation of Lipid Metabolism in High-Fat Diet-Fed Mice

Molecules, 2021
The potential biological activities of Viburnum stellato-tomentosum (VS), a plant mainly found in Costa Rica, have yet to be reported. Supplementation of VS extract for 17 weeks significantly decreased body weight gain, fat weight, fasting glucose ...
Seona Cho, Hwa Lee, Jisu Han, Haneul Lee, Rosales Ovares Kattia, Zamora Villalobos Nelson, Sangho Choi, Soo-Yong Kim, Ho-Yong Park, Hye Gwang Jeong, Tae-Sook Jeong   +10 more
doaj   +1 more source

Extracellular Signal-Regulated Kinase Is a Direct Target of the Anti-Inflammatory Compound Amentoflavone Derived from Torreya nucifera

Mediators of Inflammation, 2013
Amentoflavone is a biflavonoid compound with antioxidant, anticancer, antibacterial, antiviral, anti-inflammatory, and UV-blocking activities that can be isolated from Torreya nucifera, Biophytum sensitivum, and Selaginella tamariscina.
Jueun Oh, Ho Sik Rho, Yanyan Yang, Ju Young Yoon, Jongsung Lee, Yong Deog Hong, Hyeon Chung Kim, Sun Shim Choi, Tae Woong Kim, Song Seok Shin, Jae Youl Cho   +10 more
doaj   +1 more source

Flavonoids as Putative Epi-Modulators: Insight into Their Binding Mode with BRD4 Bromodomains Using Molecular Docking and Dynamics

Biomolecules, 2018
Flavonoids are widely recognized as natural polydrugs, given their anti-inflammatory, antioxidant, sedative, and antineoplastic activities. Recently, different studies showed that flavonoids have the potential to inhibit bromodomain and extraterminal ...
Fernando D. Prieto-Martínez, José L. Medina-Franco   +1 more
doaj   +1 more source

Mechanism of ClFLS1 regulated amentoflavone biosynthesis in mediating drought and cold stress tolerance in Cunninghamia lanceolata

Industrial Crops and Products
Amentoflavone, a natural biflavonoid with anti-inflammatory, antitumor, vasodilatory, hypoglycemic, and antioxidant properties, is widely used in healthcare. Cunninghamia lanceolata (Lamb.) Hook (C.
Lingting Wu, Yao Zheng, Kairan Li, Jinglin Yang, Yu Huang, Zhaoyang Meng, Lichang Liu, Yu Feng, Hongxuan Lv, Dan Peng, Bo Zhou   +10 more
doaj   +1 more source

Amentoflavone Mitigates Cyclophosphamide-Induced Pulmonary Toxicity: Involvement of -SIRT-1/Nrf2/Keap1 Axis, JAK-2/STAT-3 Signaling, and Apoptosis

Medicina, 2023
Background and objectives: Cyclophosphamide (CPA) is an alkylating agent that is used for the management of various types of malignancies and as an immunosuppressive agent for the treatment of immunological disorders.
Mohamed F. Balaha, Ahmed A. Alamer, Rana M. Aldossari, Alhussain H. Aodah, Azza I. Helal, Ahmed M. Kabel   +5 more
doaj   +1 more source