Results 11 to 20 of about 3,471 (217)

Insights Into Amentoflavone: A Natural Multifunctional Biflavonoid [PDF]

Frontiers in Pharmacology, 2021
Amentoflavone is an active phenolic compound isolated from Selaginella tamariscina over 40 years. Amentoflavone has been extensively recorded as a molecule which displays multifunctional biological activities.
Xifeng Xiong, Nan Tang, Xudong Lai, Jinli Zhang, Weilun Wen, Xiaojian Li, Aiguo Li, Yanhua Wu, Zhihe Liu   +8 more
doaj   +3 more sources

Amentoflavone Induces Autophagy And Modulates P53

Cell Journal, 2018
Objective Amentoflavone is the main component of Selaginella tamariscina widely known as an oriental traditional medicinal stuff that has been known to have a variety of medicinal effects such as the induction of apoptosis, anti- metastasis, and anti ...
Moon-Moo Kim
doaj   +3 more sources

Amentoflavone Exerts Anti-Neuroinflammatory Effects by Inhibiting TLR4/MyD88/NF-κB and Activating Nrf2/HO-1 Pathway in Lipopolysaccharide-Induced BV2 Microglia

Mediators of Inflammation, 2022
Background. Amentoflavone, a natural biflavone, exerts anti-inflammation, antioxidation, and antiapoptosis effects on many diseases. However, the mechanism of amentoflavone on neuroinflammation-related diseases has not been comprehensively examined ...
Shikuo Rong, Chunrong Yang, Feng Wang, Yiyang Wu, Kuishen Sun, Tao Sun, Zeyu Wu   +6 more
doaj   +1 more source

Quantum computational investigations and molecular docking studies on amentoflavone [PDF]

Heliyon, 2021
Chagas disease is a neglected tropical disease caused by the protozoan parasite Trypanosoma cruzi, with approximately 6-7 million people infected worldwide, becoming a public health problem in tropical countries, thus generating an increasing demand for the development of more effective drugs, due to the low efficiency of the existing drugs.
Márcia M. Marinho, Francisco Wagner Q. Almeida-Neto, Emanuelle M. Marinho, Leonardo P. da Silva, Ramon R.P.P.B. Menezes, Ricardo P. dos Santos, Emmanuel S. Marinho, Pedro de Lima-Neto, Alice M.C. Martins   +8 more
openaire   +3 more sources

Inhibitory effect of Selaginella doederleinii hieron on human cytochrome P450

Frontiers in Pharmacology, 2023
Introduction:Selaginella doederleinii Hieron is a traditional Chinese herbal medicine, the ethyl acetate extract from Selaginella doederleinii (SDEA) showed favorable anticancer potentials.
Fei Lin, Xinhua Lin, Xuewen Wang, Guanghui Mei, Bing Chen, Hong Yao, Lingyi Huang   +6 more
doaj   +1 more source

Antiviral Effect of Amentoflavone Against Influenza Viruses. [PDF]

Int J Mol Sci
Amentoflavone (AF) is a biflavonoid compound found in many plants. In this study, we first demonstrate that AF has a potent antiviral effect against the influenza virus via the inhibition of viral attachment and virucidal effects. The anti-influenza-viral effect of AF was evaluated using green fluorescent protein-tagged Influenza A virus (IAV) with ...
Cho WK, Choi HJ, Ahmad SS, Choi I, Ma JY.   +4 more
europepmc   +3 more sources

Exploring Phytochemicals of Traditional Medicinal Plants Exhibiting Inhibitory Activity Against Main Protease, Spike Glycoprotein, RNA-dependent RNA Polymerase and Non-Structural Proteins of SARS-CoV-2 Through Virtual Screening

Frontiers in Pharmacology, 2021
Severe Acute Respiratory Syndrome Corona Virus 2 (SARS-CoV-2) being a causative agent for global pandemic disease nCOVID’19, has acquired much scientific attention for the development of effective vaccines and drugs.
Saranya Nallusamy, Jayakanthan Mannu, Caroline Ravikumar, Kandavelmani Angamuthu, Bharathi Nathan, Kumaravadivel Nachimuthu, Gnanam Ramasamy, Raveendran Muthurajan, Mohankumar Subbarayalu, Kumar Neelakandan   +9 more
doaj   +1 more source

Effects of Amentoflavone on Anti-inflammation and Cytoprotection [PDF]

Asian Journal of Beauty and Cosmetology, 2016
목적: 본 연구의 목적은 amentoflavone의 항염증 및 세포 보호 효과를 확인하여 화장품, 의약품 원료로서의 가능성을 검증하는데 있다 . 방법: Amentoflavone의 항염증 효과를 확인하기 위하여, qRT-PCR를 이용하여 TNF-α, IL-6와 같은in flammatory cytokine의 발현량을 측정하였다. 그리고 NF-κB의 발현량을 확인하기 위해 NF-κB rpomoter luciferase assay를 수행하였다.
Songjeong Lee, Hyo Sun Han, In-Sook An, Kyu Joong Ahn   +3 more
openaire   +1 more source

Amentoflavone-Enriched Selaginella rossii Protects against Ultraviolet- and Oxidative Stress-Induced Aging in Skin Cells

Life, 2022
Selaginellaceae plants are used in cosmetics to limit skin aging. This study is the first to investigate the anti-aging effects of Selaginella rossii (SR) on ultraviolet B (UVB)- and oxidative stress-induced skin cells.
Hwa Lee, Soo-Yong Kim, Sang Woo Lee, Sehan Kwak, Hulin Li, Renzhe Piao, Ho-Yong Park, Sangho Choi, Tae-Sook Jeong   +8 more
doaj   +1 more source

Anticytotoxin Effects of Amentoflavone to Pneumolysin

Biological & Pharmaceutical Bulletin, 2017
Pneumolysin (PLY) is a devastating bacterial protein toxin of Streptococcus pneumoniae that punctures the cytomembrane, leading to pathological reactions, such as cell disruption and inflammation. Drugs capable of closely impacting the toxin are considered advantageous in the treatment of bacterial infections.
Xiaoran, Zhao, Bowen, Liu, Shui, Liu, Lin, Wang, Jianfeng, Wang   +4 more
openaire   +3 more sources