Results 11 to 20 of about 2,074 (130)

Amentoflavone as an Ally in the Treatment of Cutaneous Leishmaniasis: Analysis of Its Antioxidant/Prooxidant Mechanisms

Frontiers in Cellular and Infection Microbiology, 2021
Treatment of leishmaniasis is a challenging subject. Although available, chemotherapy is limited, presenting toxicity and adverse effects. New drugs with antileishmanial activity are being investigated, such as antiparasitic compounds derived from plants.
Yasmin Silva Rizk, Sandy Santos-Pereira, Luiza Gervazoni, Daiana de Jesus Hardoim, Flávia de Oliveira Cardoso, Celeste da Silva Freitas de Souza, Marcelo Pelajo-Machado, Marcelo Pelajo-Machado, Carlos Alexandre Carollo, Carla Cardozo Pinto de Arruda, Elmo Eduardo Almeida-Amaral, Tânia Zaverucha-do-Valle, Kátia da Silva Calabrese   +12 more
doaj   +1 more source

Inhibitory effect of Selaginella doederleinii hieron on human cytochrome P450

Frontiers in Pharmacology, 2023
Introduction:Selaginella doederleinii Hieron is a traditional Chinese herbal medicine, the ethyl acetate extract from Selaginella doederleinii (SDEA) showed favorable anticancer potentials.
Fei Lin, Xinhua Lin, Xuewen Wang, Guanghui Mei, Bing Chen, Hong Yao, Lingyi Huang   +6 more
doaj   +1 more source

Amentoflavone, a Preferentially TGF-β Receptor 1 Inhibitor, Alleviates Cardiac Remodeling and Dysfunction Through Modulating the TGF-β/Smad and MAPK Signaling Pathways. [PDF]

Phytother Res
Amentoflavone, a preferentially TGF‐ββ receptor 1 inhibitor, attenuates transverse aortic constriction (TAC)‐triggered cardiac hypertrophy, fibrosis, and dysfunction by suppressing downstream Smad and MAPK signaling cascades in cardiomyocytes and cardiac fibroblasts.
Wu J, Zhao C, Li X, Guo X, Tan W, Zhou L, Zhang Y, Zhang J, Zheng S, Zeng C, Wu G.   +10 more
europepmc   +2 more sources

Exploring Phytochemicals of Traditional Medicinal Plants Exhibiting Inhibitory Activity Against Main Protease, Spike Glycoprotein, RNA-dependent RNA Polymerase and Non-Structural Proteins of SARS-CoV-2 Through Virtual Screening

Frontiers in Pharmacology, 2021
Severe Acute Respiratory Syndrome Corona Virus 2 (SARS-CoV-2) being a causative agent for global pandemic disease nCOVID’19, has acquired much scientific attention for the development of effective vaccines and drugs.
Saranya Nallusamy, Jayakanthan Mannu, Caroline Ravikumar, Kandavelmani Angamuthu, Bharathi Nathan, Kumaravadivel Nachimuthu, Gnanam Ramasamy, Raveendran Muthurajan, Mohankumar Subbarayalu, Kumar Neelakandan   +9 more
doaj   +1 more source

Amentoflavone protects hippocampal neurons: anti-inflammatory, antioxidative, and antiapoptotic effects

Neural Regeneration Research, 2015
Amentoflavone is a natural biflavone compound with many biological properties, including anti-inflammatory, antioxidative, and neuroprotective effects. We presumed that amentoflavone exerts a neuroprotective effect in epilepsy models.
Zhen Zhang, Tao Sun, Jian-guo Niu, Zhen-quan He, Yang Liu, Feng Wang   +5 more
doaj   +1 more source

Data on the anti-tumor effects of Selaginella tamariscina extract and amentoflavone combined with doxorubicin in mice

Data in Brief, 2017
Here, we report animal experimental data associated with the article entitled “AKR1B10-inhibitory Selaginella tamariscina extract and amentoflavone decrease the growth of A549 human lung cancer cells in vitro and in vivo“ (Jung et al., 2017) [1].
Chang Gun Lee, Eun Ha Lee, Cheol-Ho Pan, Kyungsu Kang, Ki-Jong Rhee   +4 more
doaj   +1 more source

Amentoflavone-Enriched Selaginella rossii Protects against Ultraviolet- and Oxidative Stress-Induced Aging in Skin Cells

Life, 2022
Selaginellaceae plants are used in cosmetics to limit skin aging. This study is the first to investigate the anti-aging effects of Selaginella rossii (SR) on ultraviolet B (UVB)- and oxidative stress-induced skin cells.
Hwa Lee, Soo-Yong Kim, Sang Woo Lee, Sehan Kwak, Hulin Li, Renzhe Piao, Ho-Yong Park, Sangho Choi, Tae-Sook Jeong   +8 more
doaj   +1 more source

Amentoflavone Induces Autophagy And Modulates P53

Cell Journal, 2018
Objective Amentoflavone is the main component of Selaginella tamariscina widely known as an oriental traditional medicinal stuff that has been known to have a variety of medicinal effects such as the induction of apoptosis, anti- metastasis, and anti ...
Moon-Moo Kim
doaj   +1 more source

New Insights on Structures Forming the Lignin-Like Fractions of Ancestral Plants

Frontiers in Plant Science, 2021
In the present work, lignin-like fractions were isolated from several ancestral plants –including moss (Hypnum cupressiforme and Polytrichum commune), lycophyte (Selaginella kraussiana), horsetail (Equisetum palustre), fern (Nephrolepis cordifolia and ...
Jorge Rencoret, Ana Gutiérrez, Gisela Marques, José C. del Río, Yuki Tobimatsu, Pui Ying Lam, Marta Pérez-Boada, Francisco Javier Ruiz-Dueñas, José M. Barrasa, Angel T. Martínez   +9 more
doaj   +1 more source

Tissue-Specific Profiling of Biflavonoids in Ginkgo (Ginkgo biloba L.)

Plants, 2022
Biflavonoids are flavonoid dimers that are much less studied than monomeric flavonoids. Their precise distribution among plants and their role in plants is still unknown.
Marija Kovač Tomas, Iva Jurčević, Dunja Šamec   +2 more
doaj   +1 more source