Competitive cyclization of ethyl trifluoroacetoacetate and methyl ketones with 1,3-diamino-2-propanol into hydrogenated oxazolo- and pyrimido-condensed pyridones. [PDF]
Kushch SO +8 more
europepmc +1 more source
A retrospective 9-years overview of sulfated polyborate as a robust catalyst for organic transformations. [PDF]
Chhaperwal P +4 more
europepmc +1 more source
Innovative synthesis of antimicrobial Biginelli compounds using a recyclable iron oxide-based magnetic nanocatalyst. [PDF]
Taravati A +3 more
europepmc +1 more source
Structural reassignment of compound 968, an allosteric glutaminase inhibitor. [PDF]
Albertelli LA +3 more
europepmc +1 more source
Synthesis of some new pyrimidine-based pyrene/benzochromene hybrids as EGFR kinase inhibitors in HCT-116 cancer cells through apoptosis. [PDF]
Mohammed YAA +4 more
europepmc +1 more source
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Biginelli reaction: an overview
Tetrahedron Letters, 2016Abstract Biginelli reaction involves acid-catalyzed one-pot synthesis of 3,4-dihydropyrimidin-2(1H)-ones (DHPMs) using easily-accessible starting materials, namely, aldehyde, active methylene compound and (thio)urea. DHPMs have stimulated resurgence of interest in the past two decades due to their wide ranging pharmacological activities and presence ...
Arindam Mukhopadhyay +1 more
exaly +2 more sources
The utilization of the Biginelli reaction, a one-pot condensation of an aldehyde, a β-keto ester, and urea, is described. This reaction involves a number of individual steps, each of which is accessible to first-year organic students. The product, a 3,4-dihydropyrimidinone, is a member of a medicinally useful class of compounds.
Michael S. Holden, R. David Crouch
openaire +1 more source
2‐Phenacylbenzothiazole in the Biginelli Reaction.
ChemInform, 2002AbstractFor Abstract see ChemInform Abstract in Full Text.
I. B. Dzvinchuk +2 more
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An Inexpensive Protocol for Biginelli Reaction
Synthetic Communications, 2004AbstractFor Abstract see ChemInform Abstract in Full Text.
A. Manjula +2 more
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