Results 141 to 150 of about 1,953 (199)

Novel Hybrid Heterocycles Based on 1,4-Diphenylpiperazine Moiety: Synthesis via Hantzsch and Biginelli Reactions, Molecular Docking Simulation, and Antimicrobial Activities. [PDF]

ACS Omega
Diab HM, Salem ME, Abdellatif M, Soliman MM, Abdelhamid IA, Elwahy AHM, Raza N, El-Gabry YA.   +7 more
europepmc   +1 more source

2-Azidobenzaldehyde-Enabled Construction of Quinazoline Derivatives: A Review. [PDF]

Int J Mol Sci
Qiu W, Zhan D, Ma X, Zhang X.
europepmc   +1 more source

Multicomponent Green Synthesis Involving Aryl Aldehydes and Trapped Enols: Dimerization over Cyclization. [PDF]

ACS Omega
Zingales SK, Gibson M, Tapia-Hernandez J, Jenkins K, Munzing M, Dickerson G, Speikers S, Frazer DJ, Padgett CW, Wentzel MT.   +9 more
europepmc   +1 more source

Competitive cyclization of ethyl trifluoroacetoacetate and methyl ketones with 1,3-diamino-2-propanol into hydrogenated oxazolo- and pyrimido-condensed pyridones. [PDF]

Beilstein J Org Chem
Kushch SO, Goryaeva MV, Burgart YV, Ezhikova MA, Kodess MI, Slepukhin PA, Volobueva AS, Zarubaev VV, Saloutin VI.   +8 more
europepmc   +1 more source

A retrospective 9-years overview of sulfated polyborate as a robust catalyst for organic transformations. [PDF]

RSC Adv
Chhaperwal P, Soni S, Teli S, Rundla HK, Agarwal S.   +4 more
europepmc   +1 more source

Innovative synthesis of antimicrobial Biginelli compounds using a recyclable iron oxide-based magnetic nanocatalyst. [PDF]

Sci Rep
Taravati A, Nouri M, Poursattar Marjani A, Akbari Dilmaghani K.   +3 more
europepmc   +1 more source

The Biginelli Reaction Is a Urea-Catalyzed Organocatalytic Multicomponent Reaction [PDF]

The Journal of Organic Chemistry, 2015
The recently developed artificial force induced reaction (AFIR) method was applied to search systematically all possible multicomponent pathways for the Biginelli reaction mechanism. The most favorable pathway starts with the condensation of the urea and benzaldehyde, followed by the addition of ethyl acetoacetate.
Maneeporn, Puripat, Romain, Ramozzi, Miho, Hatanaka, Waraporn, Parasuk, Vudhichai, Parasuk, Keiji, Morokuma   +5 more
openaire   +3 more sources

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Biginelli reaction: an overview

Tetrahedron Letters, 2016
Abstract Biginelli reaction involves acid-catalyzed one-pot synthesis of 3,4-dihydropyrimidin-2(1H)-ones (DHPMs) using easily-accessible starting materials, namely, aldehyde, active methylene compound and (thio)urea. DHPMs have stimulated resurgence of interest in the past two decades due to their wide ranging pharmacological activities and presence ...
Arindam Mukhopadhyay, Jarugu Narasimha Moorthy   +1 more
exaly   +2 more sources

The Biginelli Reaction

Journal of Chemical Education, 2001
The utilization of the Biginelli reaction, a one-pot condensation of an aldehyde, a β-keto ester, and urea, is described. This reaction involves a number of individual steps, each of which is accessible to first-year organic students. The product, a 3,4-dihydropyrimidinone, is a member of a medicinally useful class of compounds.
Michael S. Holden, R. David Crouch
openaire   +1 more source