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The Role of Biglycan in the Heart

Connective Tissue Research, 2008
Biglycan, a member of the small leucine rich proteoglycan family, is known to be expressed in almost every tissue of our body. Although there are increasing amount of data on the biological role of biglycan, its cardiac function is still not totally clarified.
Erika, Bereczki, Miklós, Sántha
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Biglycan knockout mice: New models for musculoskeletal diseases

Glycoconjugate Journal, 2002
Biglycan is a Class I Small Leucine Rich Proteoglycans (SLRP) that is localized on human chromosome Xq28-ter. The conserved nature of its intron-exon structure and protein coding sequence compared to decorin (another Class I SLRP) indicates the two genes may have arisen from gene duplication. Biglycan contains two chondroitin sulfate glycosaminoglycan (
Marian F, Young   +3 more
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Expression and significance of biglycan in endometrial cancer

Archives of Gynecology and Obstetrics, 2013
This study aimed to determine the expression level of biglycan in different lesion properties of endometrium and to investigate the possible function and prognostic value of biglycan in endometrial cancer.Immunohistochemical staining (IHC) and quantitative realtime reverse transcription polymerase chain reaction (qRT-PCR) were used to determine the ...
Yang, Liu   +6 more
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cDNA sequence for bovine biglycan (PGI) protein core

Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression, 1993
The nucleotide sequence of the protein core for bovine aortic smooth muscle cell biglycan was determined using recombinant DNA technology. Analysis of the deduced amino acid sequence for bovine biglycan revealed a striking homology, 94.6% and 95.7%, to human and rat biglycan, respectively.
M A, Torok, S A, Evans, J A, Marcum
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Developmental regulation of biglycan expression in muscle and tendon

Muscle & Nerve, 2006
AbstractBiglycan is an extracellular ligand for the dystrophin‐associated protein complex (DAPC) that is upregulated in both dystrophic and regenerating muscle. Biglycan also binds to collagen VI, mutations of which cause a congenital muscular dystrophy (Ullrich's; UCMD) that is also characterized by connective tissue abnormalities.
Beatrice E, Lechner   +3 more
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Biglycan and Decorin Expression and Distribution in Palatal Adhesion

Journal of Dental Research, 2017
Previous studies demonstrated that chondroitin sulfate proteoglycans (CSPGs) on apical surfaces of palatal medial edge epithelial (MEE) cells were necessary for palatal adhesion. In this study, we identified 2 proteoglycans, biglycan and decorin, that were expressed in the palatal shelves prior to adhesion.
I, Ibrahim   +3 more
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Transcriptional and posttranscriptional regulators of biglycan in cardiac fibroblasts

Basic Research in Cardiology, 2009
Biglycan, a small leucine-rich proteoglycan, is essential for scar formation and preservation of hemodynamic function after myocardial infarction, as shown in biglycan-knockout mice. Because of this important role in cardiac pathophysiology, we aimed to identify regulators of biglycan expression and posttranslational modifications in cardiac ...
Tiede, Karen   +2 more
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Biglycan PG-S1, PGI, byglycan

1998
S AYAD   +4 more
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Lack of biglycan reduces contact hypersensitivity in mice

Contact Dermatitis, 2018
Philipp R. Esser   +3 more
openaire   +3 more sources

Decorin/biglycan regulation of corneal collagen fibrillogenesis

Matrix Biology, 2006
G ZHANG, H SIMPSON, D BIRK
openaire   +1 more source

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