Results 111 to 120 of about 28,403 (287)

Sita‐ and saxagliptin use and autoantibodies to autoimmune bullous diseases: A cross‐sectional study

Journal of the European Academy of Dermatology and Venereology, EarlyView.
Sören Dräger, Claudia Kauderer, Svenja Meyhöfer, Leonie Dräger, Jens U. Marquardt, Ralf J. Ludwig, Stephan Arndt, Katharina Boch, Katja Bieber   +8 more
wiley   +1 more source

Effects of long-term metformin administration associated with high-intensity interval training on physical performance, glycogen concentration, GLUT-4 content, and NMR-based metabolomics in healthy rats [PDF]

Brazilian Journal of Medical and Biological Research
The aim was to investigate the long-term effects of metformin ingestion on high-intensity interval training on performance, glycogen concentration (GC), GLUT-4 content, and metabolomics outcomes in rats.
V.J. Bastos-Silva, H. Spineli, J.C. Guimarães, K.S.C. Borbely, J.S. Ursulino, T.M. Aquino, E.S. Bento, P.P.M. Scariot, F.A.B. Sousa, G.G. de Araujo   +9 more
doaj   +1 more source

Polyethylene Shows No Concerning Evidence of Material Changes or Stress Cracking After Exposure to Chlorhexidine Gluconate and Povidone‐Iodine Irrigation Solutions

Journal of Orthopaedic Research, Volume 44, Issue 1, January 2026.
ABSTRACT Chlorhexidine‐gluconate (CHG) and povidone‐iodine (PI) are used as irrigation solutions to prevent infection in arthroplasty. This study to aimed to determine whether exposing ultra‐high molecular weight polyethylene (UHMWPE) implants to different concentrations of CHG or PI solutions would result in material or mechanical changes.
Hassaan Abdel Khalik, Moyukh O. Chakrabarti, Heera S. Marway, Michael R. Thompson, Laura Puri, Isabelle Tate, Thomas J. Wood   +6 more
wiley   +1 more source

Comparing the effects of biguanides and dipeptidyl peptidase-4 inhibitors on cardio-cerebrovascular outcomes, nephropathy, retinopathy, neuropathy, and treatment costs in diabetic patients.

PLoS ONE
BackgroundWestern guidelines often recommend biguanides as the first-line treatment for diabetes. However, dipeptidyl peptidase-4 (DPP-4) inhibitors, alongside biguanides, are increasingly used as the first-line therapy for type 2 diabetes (T2DM) in ...
Eiji Nakatani, Hiromitsu Ohno, Tatsunori Satoh, Daito Funaki, Chikara Ueki, Taku Matsunaga, Takayoshi Nagahama, Toru Tonoike, Hiromichi Yui, Akinori Miyakoshi, Yoshihiro Tanaka, Ataru Igarashi, Hiraku Kumamaru, Nagato Kuriyama, Akira Sugawara   +14 more
doaj   +1 more source

Exploring Autophagy Inducing Molecules: Targeting Diverse Pathways in Alzheimer's Disease Management

Medicinal Research Reviews, Volume 46, Issue 1, Page 272-298, January 2026.
ABSTRACT Neurodegenerative disorders, including Alzheimer's disease (AD), impose a significant burden on society due to their progressive nature and the associated healthcare costs. Autophagy, a vital cellular degradation process, has emerged as a promising therapeutic target in these disorders.
Baljinder Singh, Shubham Mahajan, Sadikalmahdi Abdella, Rehan Khan, Sanjay Garg   +4 more
wiley   +1 more source

Paving the Way Toward New Push‐Pull Superbases in the Gas Phase by an Effective DFT Approach: The Case of a New Structurally Complex Molecule, 5‐Aminopyrrole‐2‐Amidine

Journal of Physical Organic Chemistry, Volume 39, Issue 1, January 2026.
DFT calculations, carried out in the gas phase for all possible tautomers of 5‐aminopyrrole‐2‐amidine (APA), permit the estimation of their relative stabilities and allow the selection of energetically favored forms. All tautomers are push‐pull imino N‐bases that exhibit calculated basicities in the higher range of the current gas‐phase basicity scale.
Ewa Daniela Raczyńska, Jean‐Francois Gal, Pierre‐Charles Maria   +2 more
wiley   +1 more source

Biguanides antithetically regulate tumor properties by the dose-dependent mitochondrial reprogramming-driven c-Src pathway

Cell Reports Medicine
Summary: The biguanide metformin attenuates mitochondrial oxidation and is proposed as an anti-cancer therapy. However, recent clinical studies suggest increased proliferation and fatty acid β-oxidation (FAO) in a subgroup of patients with breast cancer (
Jun Hyoung Park, Kwang Hwa Jung, Dongya Jia, Sukjin Yang, Kuldeep S. Attri, Songyeon Ahn, Divya Murthy, Tagari Samanta, Debasmita Dutta, Meron Ghidey, Somik Chatterjee, Seung Yeop Han, Diego A. Pedroza, Abha Tiwari, Joyce V. Lee, Caitlin Davis, Shuting Li, Vasanta Putluri, Chad J. Creighton, Nagireddy Putluri, Lacey E. Dobrolecki, Michael T. Lewis, Jeffrey M. Rosen, José N. Onuchic, Andrei Goga, Benny Abraham Kaipparettu   +25 more
doaj   +1 more source

Antimicrobial efficiency of functionalized cellulose fibres as potential medical textiles [PDF]

, 2012
This chapter presents an overview of methods for cellulose fibres functionalization in order to introduce antimicrobial activity. In view the need for ecologically friendly textiles antimicrobial finishing is introduced, together with some strategies for
Fras Zemljič, Lidija, Gunde-Cimerman, Nina, Kralj Kunčič, Marjetka, Novak, Monika, Ristić, Tijana, Sonjak, Silva, Strnad, Simona   +6 more
core  

Study of Epigenetic Properties of Poly(HexaMethylene Biguanide) Hydrochloride (PHMB) [PDF]

, 2014
Edmond E. Creppy, Aboudoulatif Diallo, Serge Moukha, Christophe Eklu-Gadegbeku, Daniel Cros   +4 more
openalex   +1 more source

Impact of Insulin, Biguanide and Sulfonylurea Treatment on hba1c in Diabetic Patients: An Interventional Study in Rajshahi, Bangladesh

, 2023
Md Saif Zaman, Parvez Hassan, SM Shahinul Islam, Md Anayet Ullah, Md. Golam Rabbani   +4 more
openalex   +2 more sources