Results 121 to 130 of about 26,749 (243)

Comparison of SGLT2 Inhibitors for New‐Onset Proteinuria Risk in Patients With Type 2 Diabetes and Preserved Kidney Function

open access: yesDiabetes, Obesity and Metabolism, Volume 28, Issue 5, Page 4314-4325, May 2026.
ABSTRACT Aims To compare the effects of individual SGLT2 inhibitors on preventing new‐onset proteinuria in patients with type 2 diabetes and preserved kidney function. Materials and Methods A target trial emulation was performed using commercially available databases, including health checkups and claims data, between April 1, 2014 and March 31, 2023 ...
Hiroki Nobayashi   +9 more
wiley   +1 more source

Biguanide chitosan microneedles with cell-free DNA scavenging ability for psoriasis therapy

open access: yesBioactive Materials
High levels of cell-free DNA (cfDNA) induce psoriasis. Currently, the treatment of psoriasis has the disadvantages of penetration difficulty, suppression of normal immunity, and skin irritation.
Zihao Liu   +8 more
doaj   +1 more source

Evaluation of %CV and average glucose derived from pre‐ and postprandial 6‐point glucose measurements for assessing hypoglycemia risk

open access: yesJournal of Diabetes Investigation, Volume 17, Issue 5, Page 851-858, May 2026.
Six‐point pre‐ and postprandial glucose values were extracted from CGM to calculate average glucose and %CV. ROC analysis identified AG <167.7 mg/dL and %CV >21.6% as key risk factors, enabling simple detection of high hypoglycemia risk using limited glucose measurements. ABSTRACT Aims/Introduction This study determined the usefulness of coefficient of
Rika Soga   +4 more
wiley   +1 more source

Development and validation of a nomogram for predicting the risk of poor prognosis in patients with cerebral infarction

open access: yesHeliyon
Objective: To identify factors related to poor prognosis in patients with cerebral infarction (CI) and to construct and validate a personalized prediction model based on these factors.
Zhenfeng Chen   +5 more
doaj   +1 more source

Impact of renal function on antidiabetic drug selection in Japan: A real‐world analysis using the J‐DREAMS database

open access: yesJournal of Diabetes Investigation, Volume 17, Issue 5, Page 801-809, May 2026.
Using a large Japanese real‐world database, we examined antidiabetic drug selection in first and second therapy stratified by renal function and study period. The earlier initiation of SGLT2 inhibitors and GLP‐1 receptor agonists increased over time, particularly in second therapy, with prescribing patterns increasingly aligned across renal function ...
Masashi Kubota   +2 more
wiley   +1 more source

Association of glucagon‐like peptide‐1 receptor agonist use with clinical outcomes in patients with rheumatoid arthritis and type 2 diabetes

open access: yesJournal of Diabetes Investigation, Volume 17, Issue 5, Page 766-780, May 2026.
This TriNetX (US, 2016–2023) study compared clinical outcomes in patients with rheumatoid arthritis and type 2 diabetes treated with GLP‐1 receptor agonists vs DPP4 inhibitors. ABSTRACT Objectives To evaluate whether glucagon‐like peptide‐1 receptor agonists (GLP‐1 RAs) are associated with improved survival and renal outcomes in patients with ...
Yu‐Ting Yu   +4 more
wiley   +1 more source

Antimicrobial activity of different disinfectants against cariogenic microorganisms

open access: yesBrazilian Oral Research
The aim of this study was to assess the in vitro antimicrobial effects of chlorhexidine digluconate (CHX), polyhexamethylene biguanide (PHBM), and octenidine dihydrochloride (OCT) on cariogenic microorganisms by using their minimum inhibitory ...
Esra UZER CELIK   +3 more
doaj   +1 more source

Liquid oxygen-compatible filament-winding matrix resin [PDF]

open access: yes
Polyurethanes derived from hydroxy terminated polyperfluoro propylene oxide prepolymers were evaluated as matrix resins for filament wound composites which would be exposed to liquid (and 100% gaseous) oxygen environments.
Harrison, E. S.
core   +1 more source

Allosteric activation of the 5-HT_3AB receptor by mCPBG [PDF]

open access: yes, 2015
The 5-HT_3AB receptor contains three A and two B subunits in an A-A-B-A-B order. However, serotonin function at the 5-HT_3AB receptor has been shown to depend solely on the A-A interface present in the homomeric receptor. Using mutations at sites on both
Dougherty, Dennis A.   +2 more
core  

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