Results 91 to 100 of about 8,184 (204)

Cohort Study: Risk of Gallstones and Biliary Complications With Glucagon‐Like Peptide‐1 Receptor Agonists in Type 2 Diabetes

United European Gastroenterology Journal, Volume 14, Issue 5, June 2026.
ABSTRACT Background Glucagon‐like peptide‐1 receptor agonists (GLP‐1 RAs) are widely prescribed for type 2 diabetes mellitus (T2DM) because of their benefits in glycemic control, weight reduction, and cardiovascular outcomes. This study evaluated the risk of gallbladder disease among diabetic patients treated with GLP‐1 RAs.
Mohamed H. Eldesouki, Omar Alkasabrah, Mohammed Kloub, Hazem Abosheaishaa, Khaled Elfert, Arpit Sharma, Sherif Andrawes, Nikki Duong   +7 more
wiley   +1 more source

Comparing the effects of biguanides and dipeptidyl peptidase-4 inhibitors on cardio-cerebrovascular outcomes, nephropathy, retinopathy, neuropathy, and treatment costs in diabetic patients.

PLoS ONE
BackgroundWestern guidelines often recommend biguanides as the first-line treatment for diabetes. However, dipeptidyl peptidase-4 (DPP-4) inhibitors, alongside biguanides, are increasingly used as the first-line therapy for type 2 diabetes (T2DM) in ...
Eiji Nakatani, Hiromitsu Ohno, Tatsunori Satoh, Daito Funaki, Chikara Ueki, Taku Matsunaga, Takayoshi Nagahama, Toru Tonoike, Hiromichi Yui, Akinori Miyakoshi, Yoshihiro Tanaka, Ataru Igarashi, Hiraku Kumamaru, Nagato Kuriyama, Akira Sugawara   +14 more
doaj   +1 more source

The development of type 2 diabetes amongst sibling pairs in the South‐South region of Nigeria: The effect of genetics, environment and lifestyle

Diabetic Medicine, Volume 43, Issue 6, June 2026.
Abstract Introduction Type 2 diabetes is a complex condition with a multifactorial pathogenesis. The pathogenesis is considered to be polygenic due to complex interactions between genetic/epigenetic and environmental factors. The aim of this study is to determine the genetic, environmental and lifestyle factors associated with the development of type 2
Sunny Chinenye, Ibi Erekosima, Adrian H. Heald, Gesiye Bozimo, Simon G. Anderson, Samuel Seidu, Kariba Akhidue, Adaeze Ugwu, Chioma Unachukwu, Ibitrokoemi Korubo, Kingsley Chukwuemeka Patrick‐Iwuanyanwu, Victoria Gomba, Uwoma Batubo, Victoria Akanatei, Victor Ken‐Uba, Iyeopu Siminialayi, Sokiprim Akoko, Justin Ideozu, Hamilton Opurum   +18 more
wiley   +1 more source

Clinically significant hypoglycaemia in hospitalised adults: A multicentre study of 1205 episodes in the United Kingdom

Diabetic Medicine, Volume 43, Issue 6, June 2026.
Abstract Introduction and Objectives Inpatient hypoglycaemia is a serious complication of diabetes therapy, yet real‐world data on clinically significant episodes remain limited. The objectives of this study are (1) to describe the clinical and biochemical characteristics of clinically significant inpatient hypoglycaemia across multiple NHS sites, (2 ...
Charles Page, Mariam Idrissi, Sam Sherratt‐Mayhew, Aashritha Buchipudi, Amanda Ling Jie Yee, Kalyaani Persad, Aqeelah Khatoon, Amrit Rakkar, Amynta Arshad, Alexandra Lubina Solomon, Rajeev Raghavan, Lakshmi Rengarajan, Ahmed Iqbal, Pratik Choudhary, Aspasia Manta, Punith Kempegowda, DEVI Collaboration   +16 more
wiley   +1 more source

Sex‐Specific Associations of Inflammatory Biomarkers With All‐Cause and Cardiovascular Mortality Across Glycaemic Status: A Prospective UK Biobank Study

Diabetes, Obesity and Metabolism, Volume 28, Issue 6, Page 4728-4740, June 2026.
ABSTRACT Aims To explore sex‐specific heterogeneity in the prognostic discrimination of inflammatory markers for mortality across different glycaemic states. Methods This prospective cohort study included 450 438 participants from the UK Biobank (median follow‐up: 15.3 years), stratified by sex and glycaemic status.
Yawen Zhang, Menghan Li, Manrong Xu, Yun Shen, Lianxi Li, Gang Hu   +5 more
wiley   +1 more source

Risk Stratification of Chronic Kidney Disease in Adults Using Noninvasive Fibrosis Tests Based on the American Diabetes Association Algorithm

Diabetes, Obesity and Metabolism, Volume 28, Issue 6, Page 5240-5251, June 2026.
ABSTRACT Aims Although the American Diabetes Association (ADA) recently established a diagnostic algorithm for the early detection of liver fibrosis among high‐risk individuals, its implications for chronic kidney disease (CKD) risk stratification remain unclear.
Chan‐Young Jung, Hye Won Lee, Jung Il Lee, Han Ah Lee, Seung Up Kim   +4 more
wiley   +1 more source

Life‐threatening acute complications persist among individuals with type 1 diabetes in Japan: A nationwide registry‐based cross‐sectional study

Journal of Diabetes Investigation, Volume 17, Issue 6, Page 1052-1062, June 2026.
Despite insulin therapy, 18.8 and 7.8% of the patients experienced diabetic ketosis and diabetic ketoacidosis, respectively. Furthermore, 12.7 and 28.9% of the participants experienced severe hypoglycemia and hypoglycemic unawareness, respectively. Lower C‐peptide levels were associated with the incidence of these complications.
Daisuke Chujo, Akihisa Imagawa, Junnosuke Miura, Kazuma Takahashi, Toru Kikuchi, Ichiro Horie, Daisuke Yabe, Akira Shimada   +7 more
wiley   +1 more source

Can diabetic peripheral neuropathy influence the final outcome of physical performance after a combined training program in older adults? A double‐blind quasi‐experimental study

Physiological Reports, Volume 14, Issue 11, June 2026.
Illustration of the main findings of the study. Abstract This study investigated the influence of diabetic peripheral neuropathy (DPN) on physical performance in older adults with type 2 diabetes mellitus (T2DM) following a combined training (CT) program. A total of 51 older adults participated in the study divided into DPN (n = 24) and non‐DPN (n = 27)
Matheus Henrique dos Santos Lino, Marcus Vinicius Grecco, Eneida Yuri Suda, Sara Rodrigues Rosado, André Luiz de Seixas Soares, Adriana Machado Saldiba de Lima, Guilherme Carlos Brech, Julia Maria D'Andréa Greve, Angelica Castilho Alonso   +8 more
wiley   +1 more source

Pharmacological treatment patterns, factors associated with glycemic control, and renal function parameters in a real-world cohort of Hispanic adults with type 2 diabetes. [PDF]

Biomed Rep
Diaz-Martinez J, Duran C, Hospital M, Hernández-Fuentes GA, Rojas-Larios F, Kallus L, Mancilla J, Jean-Pierre A, Barthe A, Madruga-Reyes Y, Parra-Vidal L, Wagner E, Bursac Z, Montesinos-López OA, Delgado-Enciso I.   +14 more
europepmc   +1 more source

Muscle Atrophy-Related Adverse Events of Antidiabetic Drug Classes: A Pharmacovigilance Analysis Using VigiBase Data. [PDF]

J Cachexia Sarcopenia Muscle
Ueta S, Niimura T, Goda M, Ishida T, Iwata N, Takeda T, Kawada K, Miyata K, Aizawa F, Yagi K, Hamano H, Chuma M, Izawa-Ishizawa Y, Zamami Y, Ishizawa K.   +14 more
europepmc   +1 more source