Results 111 to 120 of about 22,636 (317)

Active Moderate-to-Severe Graves' Orbitopathy in a Patient With Type 2 Diabetes Mellitus and Vascular Complications [PDF]

, 2019
Background: Graves’ orbitopathy (GO) is the main extrathyroidal manifestation of Graves’ disease (GD). Diabetes mellitus (DM) has been reported to be a risk factor in patients with GO.
Biondi, B, Liccardi, A, Peschi, L, Pontieri, G, Ruggiero, A R, Urselli, F   +5 more
core   +2 more sources

Synthesis and Activity of Biomimetic Biofilm Disruptors [PDF]

, 2013
Biofilms are often associated with human bacterial infections, and the natural tolerance of biofilms to antibiotics challenges treatment. Compounds with antibiofilm activity could become useful adjuncts to antibiotic therapy.
Böttcher, Thomas, Clardy, Jon C., Kolodkin-Gal, Ilana, Kolter, Roberto Guillermo, Losick, Richard M.   +4 more
core   +1 more source

Association between sodium‐glucose cotransporter 2 inhibitor use and clinical outcomes in patients with type 2 diabetes after urinary tract infection

Diabetes, Obesity and Metabolism, EarlyView.
Abstract Aims To evaluate whether initiating sodium‐glucose cotransporter 2 inhibitors (SGLT2i) within 3 months after a urinary tract infection (UTI) is associated with improved long‐term outcomes in patients with type 2 diabetes mellitus (T2DM), compared with dipeptidyl peptidase‐4 inhibitors (DPP‐4i).
Hsiao‐Wei Wang, Ming‐Hsien Tsai, Yu‐Wei Fang, Kuo‐Cheng Lu, Joshua Wang, Chien‐Lin Lu   +5 more
wiley   +1 more source

Selective inhibition of deactivated mitochondrial complex I by biguanides.

Biochemistry, 2015
Biguanides are widely used antihyperglycemic agents for diabetes mellitus and prediabetes treatment. Complex I is the rate-limiting step of the mitochondrial electron transport chain (ETC), a major source of mitochondrial free radical production, and a ...
S. Matsuzaki, Kenneth M. Humphries
semanticscholar   +1 more source

A prospective cohort study in patients with type 2 diabetes mellitus for validation of biomarkers (PROVALID) –study design and baseline characteristics [PDF]

, 2018
Background/Aims: The prevalence of diabetes mellitus type 2 and kidney disease in these patients varies widely between European countries. Methods: In addition to store biosamples the “Prospective cohort study in patients with type 2 diabetes mellitus ...
de Zeeuw, Dick, Eder, Susanne, Heerspink, Hiddo L., Heinze, Georg, Kerschbaum, Julia, Leierer, Johannes, Mark, Patrick B., Mayer, Gert, Rosivall, Laszlo, Rossing, Peter, Wiecek, Andrzej   +10 more
core   +6 more sources

Evaluation of a stent dressing and abdominal bandage on surgical site infection following emergency equine laparotomy: A randomised controlled trial

Equine Veterinary Journal, EarlyView.
Abstract Background Surgical site infection (SSI) is a frequent complication following emergency equine laparotomy, negatively impacting equine welfare, increasing treatment costs and presenting a hospital biosecurity risk. Objectives To determine if a sutured‐on stent dressing for incisional protection during anaesthetic recovery reduced SSI following
Cajsa M. Isgren, Gina L. Pinchbeck, Shebl E. Salem, Michelle J. Hann, Neil B. Townsend, Matthew D. Cullen, Debra C. Archer   +6 more
wiley   +1 more source

Arterial stiffness, as monitored by cardio–ankle vascular index, is affected by obstructive sleep apnea, blood glucose control, and body weight – a case with 8 years follow up

International Medical Case Reports Journal, 2016
Kazuhiro Shimizu,1 Tomoyuki Yamamoto,2,3 Kohji Shirai2,4 1Department of Internal Medicine, Toho University Sakura Medical Center, Chiba, Japan; 2Department of Vascular Function, Toho University Sakura Medical Center, Chiba, Japan; 3Biological Information
Shimizu K, Yamamoto T, Shirai K
doaj  

Synergistic Interaction between Metformin and Sulfonylureas on Diclofenac-Induced Antinociception Measured Using the Formalin Test in Rats

Pain Research and Management, 2013
BACKGROUND: There is evidence that biguanides and sulfonylureas block diclofenac-induced antinociception (DIA) in rat models. However, little is known about the interaction between these hypoglycemics with respect to DIA.
Mario I Ortiz
doaj   +1 more source

Effects of Hyperglycemia and Iron Deficiency on Kidney and Heart Function in Type 2 Diabetes Disease

Biomolecules & Biomedicine, 2006
Untreated anemia can caused significant cardiac and kidney damage. The aim of this study was to investigate the efficiency of anemia and hyperglycemia treatment in type 2 diabetes and their impact on kidney and heart impairment.
Belma Aščić-Buturović, Bećir Heljić   +1 more
doaj   +1 more source

Therapeutic Repurposing of Biguanides in Cancer.

Trends in Cancer, 2021
Hongyun Zhao, K. Swanson, B. Zheng
semanticscholar   +1 more source