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The association between serum growth differentiation factor 15 and insulin resistance in women diagnosed with polycystic ovary syndrome. [PDF]
Sci RepMei Y, Li W, Chen Z, Wang M.
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Analytical Methods, 2023
Raw halloysite was purified by using sodium hexametaphosphate and utilized as the solid-phase extraction sorbent for the determination of biguanides from dietary supplements.
Huanan Huang +7 more
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Raw halloysite was purified by using sodium hexametaphosphate and utilized as the solid-phase extraction sorbent for the determination of biguanides from dietary supplements.
Huanan Huang +7 more
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The chemistry of biguanides: from synthetic routes to applications in organic chemistry
Canadian journal of chemistry (Print), 2020In this minireview, we discuss the chemistry of biguanides and their applications in catalysis. We present their super basicity as a consequence of their structure, the most efficient ways to synthesize symmetric and unsymmetric functionalized biguanides,
Solène Fortun, A. Schmitzer
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Antidiabetic Behavior of Biguanides
Journal of Pharmaceutical Sciences, 1983The existence of active electron pairs on some nitrogen atoms in phenformin hydrochloride is inferred from the presence of a hydrogen catalytic polarographic wave. This finding emphasizes the ability of biguanides to form hydrogen bridges with other molecular species such as amino acids and proteins, as well as to form coordination complexes with zinc ...
F. Vicente-Pedrós +2 more
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Diabetes Care, 1992
The main biguanides, metformin and phenformin, were introduced in 1957 as oral glucose-lowering agents to treat non-insulin-dependent diabetes mellitus (NIDDM). Phenformin was withdrawn in many countries because of an association with lactic acidosis, but metformin does not have the same risk if appropriately prescribed. Metformin is now widely used as
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The main biguanides, metformin and phenformin, were introduced in 1957 as oral glucose-lowering agents to treat non-insulin-dependent diabetes mellitus (NIDDM). Phenformin was withdrawn in many countries because of an association with lactic acidosis, but metformin does not have the same risk if appropriately prescribed. Metformin is now widely used as
openaire +3 more sources
International Journal of Toxicology, 2020
The Expert Panel for Cosmetic Ingredient Safety (Panel) reviewed the safety of Polyaminopropyl Biguanide (polyhexamethylene biguanide hydrochloride), which functions as a preservative in cosmetic products. The Panel reviewed relevant data relating to the safety of this ingredient and concluded that Polyaminopropyl Biguanide is safe in cosmetics in the
Ronald C. Shank +12 more
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The Expert Panel for Cosmetic Ingredient Safety (Panel) reviewed the safety of Polyaminopropyl Biguanide (polyhexamethylene biguanide hydrochloride), which functions as a preservative in cosmetic products. The Panel reviewed relevant data relating to the safety of this ingredient and concluded that Polyaminopropyl Biguanide is safe in cosmetics in the
Ronald C. Shank +12 more
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Demonstration of the mechanism of action of biguanides [PDF]
Acta Diabetologica Latina, 1973 Palmitic acid oxidation in rat diaphragm homogenate is depressed by biguanide concentrations that are still incapable of inhibiting oxidative phosphorylation. Glucose oxidation is not directly effected by the same biguanide concentrations: however, the inhibitory effect of palmitic acid on glucose oxidation is partly removed by biguanides.
MUNTONI S +3 more
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A direct access to heptasubstituted biguanides
Molecular Diversity, 2015An efficient and experimentally simple copper-catalyzed carbon-nitrogen bond formation for the synthesis of [Formula: see text]-arylated biguanides starting from aryl halides, carbodiimides, and 1,1,3,3-tetramethylguanidine is reported. The potential diversity of this type of reaction, easily available starting materials, and commercially available low-
I. Yavari, Manijeh Nematpour
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Thyroid, 2018
BACKGROUND It was hypothesized that the biguanides metformin and phenformin, which are anti-hyperglycemic drugs used for diabetes mellitus, would have therapeutic effects in an in vitro model of Graves' orbitopathy (GO).
Y. Han +5 more
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BACKGROUND It was hypothesized that the biguanides metformin and phenformin, which are anti-hyperglycemic drugs used for diabetes mellitus, would have therapeutic effects in an in vitro model of Graves' orbitopathy (GO).
Y. Han +5 more
semanticscholar +1 more source