Background Individuals heterozygous for germline ATM mutations have been reported to have an increased risk for breast cancer but the role for ATM genetic variants for breast cancer risk has remained unclear.
Aittomäki Kristiina +9 more
doaj +2 more sources
Два случаја на несиндромска конгенитална унилатерална хипоплазија во една фамилија [PDF]
Micromastia or breast hypoplasia is described as underdevelopment of a woman's mammary tissue. We present the case of a 15-year-old girl with unilateral micromastia, with familial predisposition.
Gucev, Zoran +6 more
core +2 more sources
Contralateral prophylactic mastectomies. Correlations between primary tumor and histological findings of controlateral breast [PDF]
Backgound: In Italy in 2015 48,000 new cases of breast carcinomas were diagnosed. Women who are diagnosed with breast cancer have a significant risk of developing contralateral breast cancer during the rest of their lives and this risk is closely ...
Amanti, Claudio +10 more
core +1 more source
INTRODUCTION: Breast cancer gene 1 and 2 (BRCA1/2) mutation carriers are at a higher risk of developing breast cancer. There are several established risk-reducing therapies.
Grzegorz J. Stępień +2 more
doaj +1 more source
A family history of breast cancer will not predict female early onset breast cancer in a population-based setting [PDF]
: BACKGROUND: An increased risk of breast cancer for relatives of breast cancer patients has been demonstrated in many studies, and having a relative diagnosed with breast cancer at an early age is an indication for breast cancer screening.
A Lucassen +36 more
core +8 more sources
The bilateral nature of breast cancer is generally accepted. Early detection of second primary breast cancers through repeated physical and x-ray examinations is difficult and uncertain. A significant number of occult second primary breast cancers have been detected in their earliest stages through generous surgical biopsy of the opposite breast at the
openaire +2 more sources
Multi-gene panel testing for hereditary cancer predisposition in unsolved high-risk breast and ovarian cancer patients. [PDF]
PurposeMany women with an elevated risk of hereditary breast and ovarian cancer have previously tested negative for pathogenic mutations in BRCA1 and BRCA2. Among them, a subset has hereditary susceptibility to cancer and requires further testing.
Adams, Sophie B +8 more
core +1 more source
Evaluation of Patients with Synchronous Bilateral Breast Cancer
Objective: Breast cancer is the most common cancer in women. The incidence of bilateral breast cancer is 2%–11%. Synchronous bilateral breast cancer is uncommon (1%–2%). Bilateral breast cancer has worse prognosis than unilateral cancer.
Elif Eda Tiken +3 more
doaj +1 more source
A case of synchronous bilateral breast cancer with different pathological responses to neoadjuvant chemotherapy with different biological character [PDF]
We report a case of synchronous locally advanced bilateral breast cancer with different pathological responses to neoadjuvant chemotherapy with different biological character.
Hirotaka Iwase +3 more
core +1 more source
Herein, we report a case of synchronous bilateral triple negative invasive ductal breast carcinoma in a patient with discrepant pathologic response to neoadjuvant chemotherapy.
Gi Won Shin +8 more
doaj +1 more source

