Results 51 to 60 of about 1,307,425 (404)
Journal of Lipid Research, 2006 Secondary bile acids, produced solely by intestinal bacteria, can accumulate to high levels in the enterohepatic circulation of some individuals and may contribute to the pathogenesis of colon cancer, gallstones, and other gastrointestinal (GI) diseases.
Jason M. Ridlon +2 more
semanticscholar +1 more source
Bile acid receptors FXR and TGR5 signaling in fatty liver diseases and therapy.
American Journal of Physiology - Gastrointestinal and Liver Physiology, 2020 Bile acid synthesis is the most significant pathway for catabolism of cholesterol and for maintaining whole body cholesterol homeostasis. Bile acids are physiological detergents that absorb, distribute, metabolize and excrete nutrients, drugs and ...
J. Chiang, Jessica M. Ferrell
semanticscholar +1 more source
АЛГОРИТМ ДИАГНОСТИКИ И ЛЕЧЕНИЯ ДИСФУНКЦИЙ БИЛИАРНОГО ТРАКТА
Архивъ внутренней медицины, 2015 In article you can find information about structure of biliary tract, pathogenesis, classification and clinical picture of biliary sludge. We pay special attention on algorithms of diagnosis of biliary tract dysfunction and proper way of doctor according
Т. Е. Полунина
doaj +1 more source
Viruses, 2020 Human norovirus (HuNoV) is the leading cause of global infectious acute gastroenteritis, causing ~20% of reported diarrheal episodes. Typically, GII.4 strains cause 50–70% of yearly outbreaks, and pandemic waves of disease approximately every 2–7 years ...
Michael L. Mallory +4 more
doaj +1 more source
Frontiers in Oncology, 2022 BackgroundCholangiocarcinoma (CCA) is one of the most aggressive malignancies, lacking novel diagnostic and prognostic biomarkers. Exosome noncoding RNAs (ncRNA) were previously proposed as a potential source of biomarkers in several cancers.
Yan Pan +4 more
doaj +1 more source
Association between cholesterol-phospholipid vesicles and cholesterol crystals in human gallbladder bile [PDF]
, 1989 Rapid aggregation of cholesterol-phospholipid vesicles in gallbladder bile seems to be the first event in the production of cholesterol crystals, a prerequisite for cholesterol gallstone formation.
Jüngst, Dieter +1 more
core +1 more source
Physiological concentrations of bile acids down-regulate agonist induced secretion in colonic epithelial cells [PDF]
, 2009 In patients with bile acid malabsorption, high concentrations of bile acids enter the colon and stimulate Cl− and fluid secretion, thereby causing diarrhoea. However, deoxycholic acid (DCA), the predominant colonic bile acid, is normally present at lower
Alan F. Hofmann +45 more
core +1 more source
Transfer of locally synthesized cholesterol from intestinal wall to intestinal lymph
Journal of Lipid Research, 1968 The cholesterol-fed rat subjected to cannulation of the intestinal lymph duct and injected with acetate-2-14C has been utilized for a study of the mechanism by which cholesterol synthesized in the intestinal wall gains access to the circulation.
Jean D. Wilson, Robert T. Reinke
doaj +1 more source
The microbiota of the bilio-pancreatic system: A cohort, STROBE-compliant study [PDF]
, 2019 Background: The gut microbiota play an essential role in protecting the host against pathogenic microorganisms by modulating immunity and regulating metabolic processes.
Agrusa A. +8 more
core +1 more source
Journal of Lipid Research, 2014 Because apoB-containing lipoproteins are pro-atherogenic and their secretion by liver and intestine largely depends on microsomal triglyceride transfer protein (MTP) activity, MTP inhibition strategies are actively pursued.
Arne Dikkers +5 more
doaj +1 more source